EED (embryonic ectoderm development) - Rat Genome Database

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Gene: EED (embryonic ectoderm development) Pan paniscus
Analyze
Symbol: EED
Name: embryonic ectoderm development
RGD ID: 11860377
Description: ENCODES a protein that exhibits chromatin binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); facultative heterochromatin formation (ortholog); genomic imprinting (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Cohen-Gibson Syndrome (ortholog); exudative vitreoretinopathy 1 (ortholog); FOUND IN chromatin silencing complex (ortholog); nucleus (ortholog); pronucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polycomb protein EED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01181,295,068 - 81,330,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,902,330 - 84,937,906 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,902,330 - 84,937,906 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EED
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01181,295,068 - 81,330,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,902,330 - 84,937,906 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,902,330 - 84,937,906 (+)Ensemblpanpan1.1panPan2
EED
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,244,753 - 86,287,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,201,212 - 86,278,813 (+)EnsemblGRCh38hg38GRCh38
GRCh371185,955,795 - 85,989,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,633,463 - 85,667,429 (+)NCBINCBI36Build 36hg18NCBI36
Build 341185,633,462 - 85,667,426NCBI
Celera1183,265,529 - 83,300,439 (+)NCBICelera
Cytogenetic Map11q14.2NCBI
HuRef1182,243,000 - 82,278,147 (+)NCBIHuRef
CHM1_11185,841,580 - 85,875,590 (+)NCBICHM1_1
T2T-CHM13v2.01186,186,227 - 86,228,460 (+)NCBIT2T-CHM13v2.0
Eed
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39789,603,862 - 89,630,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl789,603,862 - 89,630,191 (-)EnsemblGRCm39 Ensembl
GRCm38789,954,654 - 89,980,976 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl789,954,654 - 89,980,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv37797,103,164 - 97,129,486 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36789,829,868 - 89,857,005 (-)NCBIMGSCv36mm8
Celera787,275,683 - 87,302,613 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map750.42NCBI
Eed
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,280,419 - 153,307,537 (-)NCBIGRCr8
mRatBN7.21143,867,875 - 143,895,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1143,867,875 - 143,894,974 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1151,808,615 - 151,835,700 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01158,985,009 - 159,012,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01151,858,916 - 151,886,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01154,189,252 - 154,216,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1154,189,260 - 154,216,340 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01160,493,753 - 160,520,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41146,563,961 - 146,591,042 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11146,642,345 - 146,669,450 (-)NCBI
Celera1142,108,258 - 142,135,298 (-)NCBICelera
Cytogenetic Map1q32NCBI
Eed
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554146,659,055 - 6,685,530 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554146,659,144 - 6,685,530 (-)NCBIChiLan1.0ChiLan1.0
EED
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12113,260,062 - 13,289,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2113,260,002 - 13,289,337 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2113,125,575 - 13,155,433 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02113,442,739 - 13,472,602 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2113,442,743 - 13,472,368 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12113,228,555 - 13,258,431 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02113,300,989 - 13,331,006 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02113,357,756 - 13,387,545 (-)NCBIUU_Cfam_GSD_1.0
Eed
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494772,451,606 - 72,483,821 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649814,051,045 - 14,083,570 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649814,050,731 - 14,082,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EED
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl920,123,857 - 20,158,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1920,123,077 - 20,158,747 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2922,382,548 - 22,417,549 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EED
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1177,496,266 - 77,531,439 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl177,496,086 - 77,531,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604348,194,395 - 48,229,592 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eed
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248453,679,096 - 3,712,176 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248453,679,163 - 3,712,153 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000062444   ⟹   ENSPPAP00000039533
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1184,902,330 - 84,937,906 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062446   ⟹   ENSPPAP00000039535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1184,902,330 - 84,937,902 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062451   ⟹   ENSPPAP00000039540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1184,903,171 - 84,937,688 (+)Ensembl
RefSeq Acc Id: XM_003832975   ⟹   XP_003833023
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBI
Mhudiblu_PPA_v01181,295,178 - 81,330,321 (+)NCBI
PanPan1.11184,902,330 - 84,937,906 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008958476   ⟹   XP_008956724
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBI
Mhudiblu_PPA_v01181,295,109 - 81,330,321 (+)NCBI
PanPan1.11184,902,330 - 84,937,906 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014346954   ⟹   XP_014202440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBI
Mhudiblu_PPA_v01181,295,109 - 81,330,321 (+)NCBI
PanPan1.11184,903,092 - 84,937,902 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933500   ⟹   XP_034789391
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBI
Mhudiblu_PPA_v01181,295,145 - 81,330,321 (+)NCBI
RefSeq Acc Id: XM_034933501   ⟹   XP_034789392
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,189,225 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,240,087 (+)NCBI
Mhudiblu_PPA_v01181,295,068 - 81,321,932 (+)NCBI
RefSeq Acc Id: XM_055093832   ⟹   XP_054949807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBI
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003833023   ⟸   XM_003832975
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CEU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014202440   ⟸   XM_014346954
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CC75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008956724   ⟸   XM_008958476
- Peptide Label: isoform X6
- UniProtKB: A0A2R9CC71 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789392   ⟸   XM_034933501
- Peptide Label: isoform X5
RefSeq Acc Id: XP_034789391   ⟸   XM_034933500
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000039540   ⟸   ENSPPAT00000062451
RefSeq Acc Id: ENSPPAP00000039535   ⟸   ENSPPAT00000062446
RefSeq Acc Id: ENSPPAP00000039533   ⟸   ENSPPAT00000062444
RefSeq Acc Id: XP_054949807   ⟸   XM_055093832
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042452 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062444.1 UniProtKB/TrEMBL
  ENSPPAT00000062446.1 UniProtKB/TrEMBL
  ENSPPAT00000062451.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100981982 UniProtKB/TrEMBL
NCBI Gene EED ENTREZGENE
PANTHER POLYCOMB PROTEIN UniProtKB/TrEMBL
  PTHR10253:SF5 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9CC71 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CC75 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CEU4 ENTREZGENE, UniProtKB/TrEMBL