CORO1A (coronin 1A) - Rat Genome Database

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Gene: CORO1A (coronin 1A) Pan paniscus
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Symbol: CORO1A
Name: coronin 1A
RGD ID: 11858687
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); actin monomer binding (inferred); INVOLVED IN actin filament organization (ortholog); calcium ion transport (ortholog); cellular response to interleukin-4 (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN glutamatergic synapse (ortholog); nucleus (ortholog); stereocilium tip (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coronin-1A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,926,030 - 30,931,532 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,294,286 - 35,299,847 (-)NCBINHGRI_mPanPan1
PanPan1.11630,549,880 - 30,555,093 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,550,383 - 30,556,196 (+)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA)
actin filament organization  (IEA,ISO)
calcium ion transport  (IEA,ISO)
cell migration  (IEA)
cell-substrate adhesion  (IEA)
cellular response to interleukin-4  (IEA,ISO)
early endosome to recycling endosome transport  (IEA,ISO)
epithelial cell migration  (IEA,ISO)
establishment of localization in cell  (IEA,ISO)
homeostasis of number of cells within a tissue  (IEA,ISO)
immunological synapse formation  (ISO)
leukocyte chemotaxis  (IEA,ISO)
natural killer cell degranulation  (IEA)
negative regulation of actin nucleation  (IEA)
negative regulation of canonical NF-kappaB signal transduction  (ISO)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of vesicle fusion  (IEA,ISO)
nerve growth factor signaling pathway  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
phagocytosis  (IEA)
phagolysosome assembly  (IEA)
positive chemotaxis  (IEA)
positive regulation of T cell activation  (IEA,ISO)
positive regulation of T cell migration  (IEA,ISO)
positive regulation of T cell proliferation  (IEA,ISO)
regulation of actin cytoskeleton organization  (IEA)
regulation of actin filament polymerization  (IEA,ISO)
regulation of actin polymerization or depolymerization  (IEA,ISO)
regulation of cell shape  (IEA,ISO)
regulation of release of sequestered calcium ion into cytosol  (IEA,ISO)
response to cytokine  (IEA,ISO)
T cell activation  (IEA,ISO)
T cell homeostasis  (IEA,ISO)
T cell migration  (IEA,ISO)
T cell proliferation  (IEA,ISO)
thymocyte migration  (IEA,ISO)
uropod organization  (IEA,ISO)
vesicle fusion  (IEA,ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CORO1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,926,030 - 30,931,532 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,294,286 - 35,299,847 (-)NCBINHGRI_mPanPan1
PanPan1.11630,549,880 - 30,555,093 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,550,383 - 30,556,196 (+)Ensemblpanpan1.1panPan2
CORO1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,183,602 - 30,189,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,182,827 - 30,189,076 (+)EnsemblGRCh38hg38GRCh38
GRCh371630,194,923 - 30,200,397 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,102,427 - 30,107,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 341630,102,448 - 30,107,898NCBI
Celera1672,594,500 - 72,599,971 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,857,375 - 27,863,041 (+)NCBIHuRef
CHM1_11631,409,355 - 31,415,021 (+)NCBICHM1_1
T2T-CHM13v2.01630,468,184 - 30,473,658 (+)NCBIT2T-CHM13v2.0
Coro1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,298,946 - 126,303,925 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,298,945 - 126,306,959 (-)EnsemblGRCm39 Ensembl
GRCm387126,699,774 - 126,704,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,699,773 - 126,707,787 (-)EnsemblGRCm38mm10GRCm38
MGSCv377133,843,288 - 133,848,268 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,490,922 - 126,495,902 (-)NCBIMGSCv36mm8
Celera7126,547,074 - 126,552,054 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
Coro1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,726,129 - 190,731,133 (-)NCBIGRCr8
mRatBN7.21181,295,561 - 181,300,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,295,562 - 181,300,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,646,783 - 189,651,767 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,832,853 - 196,837,837 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,500,261 - 189,505,244 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,123,883 - 198,128,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,123,884 - 198,128,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,102,882 - 205,107,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,852,741 - 185,857,715 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,002,622 - 186,007,596 (-)NCBI
Celera1178,953,035 - 178,958,009 (-)NCBICelera
Cytogenetic Map1q36NCBI
Coro1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,811,430 - 6,826,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,815,148 - 6,820,295 (-)NCBIChiLan1.0ChiLan1.0
CORO1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,161,850 - 18,167,915 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,160,601 - 18,167,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,740,842 - 19,746,439 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,298,321 - 18,303,918 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,298,356 - 18,303,915 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,097,136 - 18,102,732 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,012,545 - 18,018,141 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,328,371 - 18,333,968 (+)NCBIUU_Cfam_GSD_1.0
Coro1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,240,682 - 124,246,391 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,338,542 - 12,344,265 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,338,542 - 12,344,236 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CORO1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,336,898 - 18,342,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,336,813 - 18,342,381 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CORO1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,482,269 - 26,488,537 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,480,753 - 26,487,929 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660683,057,322 - 3,063,870 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coro1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,105,153 - 13,111,357 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,106,416 - 13,111,394 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSPPAT00000039980   ⟹   ENSPPAP00000017278
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,550,383 - 30,556,196 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039986   ⟹   ENSPPAP00000017284
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,551,233 - 30,554,981 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039990   ⟹   ENSPPAP00000017288
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,552,701 - 30,554,981 (+)Ensembl
RefSeq Acc Id: XM_034952188   ⟹   XP_034808079
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21830,926,030 - 30,931,532 (+)NCBI
NHGRI_mPanPan11635,294,286 - 35,299,847 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034808079 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000017278.1
  ENSPPAP00000017284.1
  ENSPPAP00000017288.1
Ensembl Acc Id: ENSPPAP00000017288   ⟸   ENSPPAT00000039990
Ensembl Acc Id: ENSPPAP00000017284   ⟸   ENSPPAT00000039986
Ensembl Acc Id: ENSPPAP00000017278   ⟸   ENSPPAT00000039980
RefSeq Acc Id: XP_034808079   ⟸   XM_034952188
- UniProtKB: A0A2R9AJM6 (UniProtKB/TrEMBL),   A0A2R9AQX3 (UniProtKB/TrEMBL)
Protein Domains
DUF1899   Trimerisation motif


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031716 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039980.1 UniProtKB/TrEMBL
  ENSPPAT00000039986.1 UniProtKB/TrEMBL
  ENSPPAT00000039990.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Coronin UniProtKB/TrEMBL
  DUF1899 UniProtKB/TrEMBL
  Trimer_CC UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100993992 UniProtKB/TrEMBL
NCBI Gene CORO1A ENTREZGENE
PANTHER PTHR10856 UniProtKB/TrEMBL
  PTHR10856:SF18 UniProtKB/TrEMBL
Pfam DUF1899 UniProtKB/TrEMBL
  Trimer_CC UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
  WD40_4 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART DUF1899 UniProtKB/TrEMBL
  DUF1900 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9AJM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AJN6_PANPA UniProtKB/TrEMBL
  A0A2R9AQX3 ENTREZGENE, UniProtKB/TrEMBL