PIWIL3 (piwi like RNA-mediated gene silencing 3) - Rat Genome Database

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Gene: PIWIL3 (piwi like RNA-mediated gene silencing 3) Pan paniscus
Analyze
Symbol: PIWIL3
Name: piwi like RNA-mediated gene silencing 3
RGD ID: 11856664
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); piRNA binding (inferred); RNA binding (inferred); INVOLVED IN regulation of translation (inferred); regulatory ncRNA-mediated gene silencing (inferred); ASSOCIATED WITH genetic disease (ortholog); oligospermia (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: piwi-like 3; piwi-like protein 3
RGD Orthologs
Human
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,622,587 - 34,705,478 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,320,755 - 37,403,651 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,678,784 - 5,721,948 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,347,633 - 23,390,380 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (ISO)
P granule  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PIWIL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,622,587 - 34,705,478 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,320,755 - 37,403,651 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,678,784 - 5,721,948 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,347,633 - 23,390,380 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensemblpanpan1.1panPan2
PIWIL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,719,034 - 24,774,720 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,719,034 - 24,774,720 (-)EnsemblGRCh38hg38GRCh38
GRCh372225,115,001 - 25,170,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,445,001 - 23,500,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 342223,439,554 - 23,495,237NCBI
Celera228,919,401 - 8,975,139 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef228,063,447 - 8,119,140 (-)NCBIHuRef
CHM1_12225,073,992 - 25,129,703 (-)NCBICHM1_1
T2T-CHM13v2.02225,180,480 - 25,236,180 (-)NCBIT2T-CHM13v2.0
LOC486307
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,035,530 - 17,063,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,036,963 - 17,061,992 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,739,185 - 18,766,762 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02617,379,223 - 17,407,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2617,380,903 - 17,406,205 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,948,385 - 18,974,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,369,622 - 17,397,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,387,029 - 17,414,680 (-)NCBIUU_Cfam_GSD_1.0
PIWIL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,835,302 - 42,869,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11442,834,819 - 42,869,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21445,566,922 - 45,600,516 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIWIL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,826,068 - 7,866,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl197,826,757 - 7,865,934 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045118,012,577 - 118,068,691 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Piwil3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474712,587,798 - 12,629,494 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000040586   ⟹   ENSPPAP00000017866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040594   ⟹   ENSPPAP00000017874
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040600   ⟹   ENSPPAP00000017880
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,347,633 - 23,390,380 (-)Ensembl
RefSeq Acc Id: XM_003814273   ⟹   XP_003814321
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22334,622,587 - 34,667,070 (-)NCBI
NHGRI_mPanPan12237,320,755 - 37,365,133 (-)NCBI
Mhudiblu_PPA_v0225,678,784 - 5,721,948 (-)NCBI
PanPan1.12223,347,633 - 23,390,380 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055105974   ⟹   XP_054961949
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22334,622,587 - 34,705,478 (-)NCBI
NHGRI_mPanPan12237,320,755 - 37,403,651 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003814321 (Get FASTA)   NCBI Sequence Viewer  
  XP_054961949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000017866.1
  ENSPPAP00000017874.1
  ENSPPAP00000017880.1
RefSeq Acc Id: XP_003814321   ⟸   XM_003814273
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000017866   ⟸   ENSPPAT00000040586
RefSeq Acc Id: ENSPPAP00000017874   ⟸   ENSPPAT00000040594
RefSeq Acc Id: ENSPPAP00000017880   ⟸   ENSPPAT00000040600
RefSeq Acc Id: XP_054961949   ⟸   XM_055105974
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AQ60 (UniProtKB/TrEMBL)
Protein Domains
PAZ   Piwi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031985 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040586.1 UniProtKB/TrEMBL
  ENSPPAT00000040594.1 UniProtKB/TrEMBL
  ENSPPAT00000040600.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
  paz domain UniProtKB/TrEMBL
InterPro PAZ_dom UniProtKB/TrEMBL
  PAZ_dom_sf UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report pps:100980276 UniProtKB/TrEMBL
NCBI Gene PIWIL3 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2C UniProtKB/TrEMBL
  PIWI-LIKE PROTEIN 3 UniProtKB/TrEMBL
Pfam PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
PROSITE PAZ UniProtKB/TrEMBL
  PIWI UniProtKB/TrEMBL
SMART PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
Superfamily-SCOP SSF101690 UniProtKB/TrEMBL
  SSF53098 UniProtKB/TrEMBL
UniProt A0A2R9AKH2_PANPA UniProtKB/TrEMBL
  A0A2R9AQ60 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ASM9_PANPA UniProtKB/TrEMBL