CD8A (CD8 subunit alpha) - Rat Genome Database

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Gene: CD8A (CD8 subunit alpha) Pan paniscus
Analyze
Symbol: CD8A
Name: CD8 subunit alpha
RGD ID: 11853704
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase binding (ortholog); INVOLVED IN calcium-mediated signaling (ortholog); cell surface receptor signaling pathway (ortholog); cytotoxic T cell differentiation (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH anogenital venereal wart (ortholog); brain infarction (ortholog); CD8 Deficiency, Familial (ortholog); FOUND IN cell surface (ortholog); receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD8a molecule; T-cell surface glycoprotein CD8 alpha chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,579,706 - 39,603,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,582,466 - 39,606,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A86,832,559 - 86,855,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A88,376,411 - 88,383,519 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A88,377,722 - 88,382,635 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CD8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,579,706 - 39,603,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,582,466 - 39,606,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A86,832,559 - 86,855,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A88,376,411 - 88,383,519 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A88,377,722 - 88,382,635 (-)Ensemblpanpan1.1panPan2
CD8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38286,784,605 - 86,808,396 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl286,784,610 - 86,808,396 (-)EnsemblGRCh38hg38GRCh38
GRCh37287,011,728 - 87,035,519 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,865,239 - 86,871,638 (-)NCBINCBI36Build 36hg18NCBI36
Build 34286,923,391 - 86,929,725NCBI
Celera286,839,534 - 86,863,331 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef286,898,000 - 86,921,798 (-)NCBIHuRef
CHM1_1286,941,749 - 86,965,554 (-)NCBICHM1_1
T2T-CHM13v2.0286,786,504 - 86,810,303 (-)NCBIT2T-CHM13v2.0
Cd8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,350,411 - 71,356,155 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,350,411 - 71,356,157 (+)EnsemblGRCm39 Ensembl
GRCm38671,373,427 - 71,379,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,373,427 - 71,379,173 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,323,421 - 71,329,165 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,302,936 - 71,308,680 (+)NCBIMGSCv36mm8
Celera673,452,794 - 73,458,537 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.14NCBI
Cd8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84104,924,116 - 104,928,353 (+)NCBIGRCr8
mRatBN7.24103,365,804 - 103,370,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,365,804 - 103,370,040 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4108,748,755 - 108,752,992 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,523,859 - 104,528,097 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,135,733 - 103,139,970 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,217,640 - 99,243,352 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,239,115 - 99,243,351 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,993,814 - 164,022,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,589,922 - 104,594,159 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14104,834,402 - 104,838,639 (+)NCBI
Celera492,538,482 - 92,542,731 (+)NCBICelera
Cytogenetic Map4q32NCBI
Cd8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955424952,502 - 978,636 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955424952,595 - 979,159 (+)NCBIChiLan1.0ChiLan1.0
CD8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,396,022 - 38,400,508 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1738,369,414 - 38,400,508 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,080,864 - 38,085,351 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,127,938 - 39,132,423 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,127,889 - 39,132,423 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,294,729 - 38,299,212 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,330,601 - 38,335,086 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,679,136 - 38,683,623 (+)NCBIUU_Cfam_GSD_1.0
Cd8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,968,389 - 79,973,360 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936712885,458 - 890,852 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936712885,301 - 891,247 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl357,998,891 - 58,029,760 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1357,999,228 - 58,029,768 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,852,723 - 60,859,977 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11418,878,013 - 18,885,183 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1418,878,622 - 18,883,885 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666080896,572 - 903,593 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474916,564,944 - 16,569,890 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000063306   ⟹   ENSPPAP00000040390
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A88,377,722 - 88,382,635 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000063308   ⟹   ENSPPAP00000040392
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A88,377,722 - 88,382,635 (-)Ensembl
RefSeq Acc Id: XM_034953505   ⟹   XP_034809396
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,579,706 - 39,603,326 (+)NCBI
NHGRI_mPanPan12A39,582,466 - 39,606,086 (+)NCBI
Mhudiblu_PPA_v02A86,832,559 - 86,855,772 (-)NCBI
RefSeq Acc Id: XM_057301276   ⟹   XP_057157259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,579,706 - 39,603,326 (+)NCBI
NHGRI_mPanPan12A39,582,466 - 39,606,086 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034809396 (Get FASTA)   NCBI Sequence Viewer  
  XP_057157259 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040390.1
  ENSPPAP00000040392.1
RefSeq Acc Id: XP_034809396   ⟸   XM_034953505
- UniProtKB: A0A2R9CEN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000040392   ⟸   ENSPPAT00000063308
RefSeq Acc Id: ENSPPAP00000040390   ⟸   ENSPPAT00000063306
RefSeq Acc Id: XP_057157259   ⟸   XM_057301276
- UniProtKB: A0A2R9CEN0 (UniProtKB/TrEMBL)
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042853 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063306.1 UniProtKB/TrEMBL
  ENSPPAT00000063308.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD8_asu UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene CD8A ENTREZGENE
PANTHER PTHR10441 UniProtKB/TrEMBL
  T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9CEN0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CPI7_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-01-10 CD8A  CD8 subunit alpha  CD8A  CD8a molecule  Symbol and/or name change 5135510 APPROVED