CDK2AP2 (cyclin dependent kinase 2 associated protein 2) - Rat Genome Database

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Gene: CDK2AP2 (cyclin dependent kinase 2 associated protein 2) Pan paniscus
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Symbol: CDK2AP2
Name: cyclin dependent kinase 2 associated protein 2
RGD ID: 11852299
Description: INVOLVED IN negative regulation of G1/S transition of mitotic cell cycle (inferred); regulation of microtubule cytoskeleton organization (inferred); regulation of stem cell division (inferred); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); microtubule (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-dependent kinase 2-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,734,077 - 68,736,325 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,776,660 - 69,778,908 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01162,865,554 - 62,867,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,176,917 - 66,179,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,176,917 - 66,179,154 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
microtubule  (IEA)
nucleus  (IEA)
NuRD complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDK2AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,734,077 - 68,736,325 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,776,660 - 69,778,908 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01162,865,554 - 62,867,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,176,917 - 66,179,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,176,917 - 66,179,154 (-)Ensemblpanpan1.1panPan2
CDK2AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,506,497 - 67,508,162 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,506,497 - 67,508,649 (-)EnsemblGRCh38hg38GRCh38
GRCh371167,273,968 - 67,275,633 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,030,544 - 67,032,678 (-)NCBINCBI36Build 36hg18NCBI36
Celera1164,608,370 - 64,610,504 (-)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1163,603,170 - 63,605,408 (-)NCBIHuRef
CHM1_11167,157,015 - 67,159,253 (-)NCBICHM1_1
T2T-CHM13v2.01167,501,174 - 67,502,839 (-)NCBIT2T-CHM13v2.0
Cdk2ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,146,204 - 4,149,019 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,147,182 - 4,149,019 (+)EnsemblGRCm39 Ensembl
GRCm38194,096,206 - 4,099,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,097,182 - 4,099,019 (+)EnsemblGRCm38mm10GRCm38
MGSCv37194,097,351 - 4,099,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,097,351 - 4,099,017 (+)NCBIMGSCv36mm8
Celera193,968,253 - 3,969,919 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.8NCBI
Cdk2ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,819,155 - 210,822,604 (+)NCBIGRCr8
mRatBN7.21201,391,056 - 201,393,137 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,391,466 - 201,393,137 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,743,716 - 209,745,384 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,836,947 - 216,838,615 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01209,527,960 - 209,529,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,345,638 - 219,347,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,345,918 - 219,347,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,216,312 - 226,218,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,681,430 - 206,683,098 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1198,935,992 - 198,937,660 (+)NCBICelera
Cytogenetic Map1q43NCBI
Cdk2ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,981,267 - 17,984,517 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,981,267 - 17,983,480 (+)NCBIChiLan1.0ChiLan1.0
CDK2AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,969,630 - 49,971,781 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,970,160 - 49,971,457 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,580,124 - 48,582,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,892,011 - 50,894,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,892,068 - 50,908,430 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11850,105,317 - 50,107,514 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,679,848 - 49,682,045 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,474,088 - 50,476,285 (+)NCBIUU_Cfam_GSD_1.0
Cdk2ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,815,870 - 5,817,534 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,257,671 - 2,259,886 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,257,731 - 2,259,883 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK2AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl25,025,600 - 5,027,764 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.125,025,256 - 5,027,766 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,743,767 - 3,746,277 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK2AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,756,853 - 6,759,087 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16,756,909 - 6,759,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038104,034,694 - 104,036,928 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk2ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476719,027,912 - 19,030,835 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476719,028,442 - 19,030,580 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000063844   ⟹   ENSPPAP00000040924
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1166,176,917 - 66,179,154 (-)Ensembl
RefSeq Acc Id: XM_003828731   ⟹   XP_003828779
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,734,077 - 68,736,325 (-)NCBI
NHGRI_mPanPan11169,776,660 - 69,778,908 (-)NCBI
Mhudiblu_PPA_v01162,865,554 - 62,867,756 (-)NCBI
PanPan1.11166,176,917 - 66,179,154 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014346890   ⟹   XP_014202376
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,734,077 - 68,736,284 (-)NCBI
NHGRI_mPanPan11169,776,660 - 69,778,790 (-)NCBI
Mhudiblu_PPA_v01162,865,554 - 62,867,225 (-)NCBI
PanPan1.11166,176,917 - 66,178,279 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014346891   ⟹   XP_014202377
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,734,077 - 68,735,586 (-)NCBI
NHGRI_mPanPan11169,776,660 - 69,778,163 (-)NCBI
Mhudiblu_PPA_v01162,865,554 - 62,867,225 (-)NCBI
PanPan1.11166,176,917 - 66,179,148 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003828779 (Get FASTA)   NCBI Sequence Viewer  
  XP_014202376 (Get FASTA)   NCBI Sequence Viewer  
  XP_014202377 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040924
  ENSPPAP00000040924.1
RefSeq Acc Id: XP_003828779   ⟸   XM_003828731
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CG83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014202377   ⟸   XM_014346891
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_014202376   ⟸   XM_014346890
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000040924   ⟸   ENSPPAT00000063844


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043090 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063844.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1300 UniProtKB/TrEMBL
InterPro DOC_1/2 UniProtKB/TrEMBL
KEGG Report pps:100989908 UniProtKB/TrEMBL
NCBI Gene CDK2AP2 ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  PTHR22607 UniProtKB/TrEMBL
Pfam CDK2AP UniProtKB/TrEMBL
PIRSF CDK2-associated_p2 UniProtKB/TrEMBL
UniProt A0A2R9CG83 ENTREZGENE, UniProtKB/TrEMBL