DRD3 (dopamine receptor D3) - Rat Genome Database

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Gene: DRD3 (dopamine receptor D3) Pan paniscus
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Symbol: DRD3
Name: dopamine receptor D3
RGD ID: 11849547
Description: ENCODES a protein that exhibits D1 dopamine receptor binding (ortholog); dopamine neurotransmitter receptor activity, coupled via Gi/Go (ortholog); protein domain specific binding (ortholog); INVOLVED IN acid secretion (ortholog); adenylate cyclase-activating dopamine receptor signaling pathway (ortholog); adenylate cyclase-inhibiting dopamine receptor signaling pathway (ortholog); PARTICIPATES IN dopamine signaling pathway; dopamine signaling pathway via D2 family of receptors; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH Alzheimer's disease (ortholog); amnestic disorder (ortholog); amphetamine abuse (ortholog); FOUND IN apical part of cell (ortholog); cell projection (ortholog); dopaminergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: D(3) dopamine receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13118,187,636 - 118,237,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3118,187,636 - 118,237,403 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03111,265,834 - 111,317,176 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acid secretion  (ISO)
adenylate cyclase-activating dopamine receptor signaling pathway  (ISO)
adenylate cyclase-inhibiting dopamine receptor signaling pathway  (ISO)
arachidonic acid secretion  (ISO)
autophagy  (ISO)
behavioral response to cocaine  (ISO)
cellular calcium ion homeostasis  (ISO)
circadian regulation of gene expression  (ISO)
G protein-coupled receptor internalization  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
gastric emptying  (ISO)
locomotory behavior  (ISO)
musculoskeletal movement, spinal reflex action  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of blood pressure  (ISO)
negative regulation of dopamine receptor signaling pathway  (ISO)
negative regulation of oligodendrocyte differentiation  (ISO)
negative regulation of protein kinase B signaling  (ISO)
negative regulation of protein secretion  (ISO)
negative regulation of sodium:proton antiporter activity  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cytokinesis  (ISO)
positive regulation of dopamine receptor signaling pathway  (ISO)
positive regulation of mitotic nuclear division  (ISO)
positive regulation of renal sodium excretion  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
prepulse inhibition  (ISO)
regulation of blood volume by renin-angiotensin  (ISO)
regulation of circadian sleep/wake cycle, sleep  (ISO)
regulation of dopamine secretion  (ISO)
regulation of lipid metabolic process  (ISO)
regulation of locomotion  (ISO)
regulation of locomotion involved in locomotory behavior  (ISO)
regulation of multicellular organism growth  (ISO)
regulation of neurotransmitter uptake  (ISO)
regulation of postsynaptic neurotransmitter receptor internalization  (ISO)
response to amphetamine  (ISO)
response to cocaine  (ISO)
response to ethanol  (ISO)
response to histamine  (ISO)
response to morphine  (ISO)
response to xenobiotic stimulus  (ISO)
visual learning  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
DRD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13118,187,636 - 118,237,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3118,187,636 - 118,237,403 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03111,265,834 - 111,317,176 (-)NCBIMhudiblu_PPA_v0panPan3
DRD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3114,127,580 - 114,199,407 (-)EnsemblGRCh38hg38GRCh38
GRCh383114,127,580 - 114,199,407 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373113,846,427 - 113,918,254 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363115,330,247 - 115,380,589 (-)NCBINCBI36hg18NCBI36
Celera3112,255,976 - 112,306,017 (-)NCBI
Cytogenetic Map3q13.31NCBI
HuRef3111,221,547 - 111,271,509 (-)NCBIHuRef
CHM1_13113,810,902 - 113,860,923 (-)NCBICHM1_1
Drd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391643,574,285 - 43,646,353 (+)NCBIGRCm39mm39
GRCm39 Ensembl1643,574,389 - 43,643,295 (+)Ensembl
GRCm381643,754,015 - 43,825,982 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1643,754,026 - 43,822,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv371643,762,355 - 43,822,952 (+)NCBIGRCm37mm9NCBIm37
MGSCv361643,681,574 - 43,742,171 (+)NCBImm8
Celera1644,116,581 - 44,178,828 (+)NCBICelera
Cytogenetic Map16B4NCBI
cM Map1628.44NCBI
Drd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,879,689 - 56,931,901 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1161,822,077 - 61,874,327 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01161,819,102 - 61,883,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01160,955,136 - 61,016,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,446,901 - 58,520,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11158,504,489 - 58,578,178 (-)NCBI
Celera1156,432,639 - 56,484,538 (-)NCBICelera
Cytogenetic Map11q21NCBI
Drd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542714,219,594 - 14,252,178 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542714,219,519 - 14,252,178 (-)NCBIChiLan1.0ChiLan1.0
DRD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13318,369,362 - 18,414,465 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3318,372,865 - 18,412,277 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3318,479,435 - 18,522,131 (-)NCBI
ROS_Cfam_1.03318,617,139 - 18,660,020 (-)NCBI
UMICH_Zoey_3.13318,420,282 - 18,463,050 (-)NCBI
UNSW_CanFamBas_1.03318,472,599 - 18,515,180 (-)NCBI
UU_Cfam_GSD_1.03319,017,562 - 19,060,421 (-)NCBI
Drd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602135,897,271 - 135,945,568 (+)NCBI
SpeTri2.0NW_0049365361,580,732 - 1,616,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13145,771,510 - 145,819,173 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113145,769,294 - 145,817,997 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213155,329,068 - 155,375,118 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12266,683,987 - 66,737,645 (+)NCBI
ChlSab1.1 Ensembl2266,691,177 - 66,736,690 (+)Ensembl
Vero_WHO_p1.0NW_02366604199,729,580 - 99,781,727 (-)NCBI
Drd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473134,318,733 - 34,369,111 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044021   ⟹   ENSPPAP00000021221
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3118,187,636 - 118,237,403 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044023   ⟹   ENSPPAP00000021223
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3118,187,636 - 118,237,403 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044029   ⟹   ENSPPAP00000021229
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3118,205,897 - 118,230,237 (-)Ensembl
RefSeq Acc Id: XM_003825120   ⟹   XP_003825168
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.13118,187,636 - 118,237,403 (-)NCBI
Mhudiblu_PPA_v03111,265,836 - 111,317,159 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034957121   ⟹   XP_034813012
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03111,265,834 - 111,317,176 (-)NCBI
RefSeq Acc Id: XM_034957122   ⟹   XP_034813013
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03111,265,834 - 111,317,175 (-)NCBI
RefSeq Acc Id: XM_034957123   ⟹   XP_034813014
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03111,265,835 - 111,317,172 (-)NCBI
RefSeq Acc Id: XM_034957124   ⟹   XP_034813015
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03111,265,835 - 111,317,167 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_003825168   ⟸   XM_003825120
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_034813012   ⟸   XM_034957121
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034813013   ⟸   XM_034957122
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034813014   ⟸   XM_034957123
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034813015   ⟸   XM_034957124
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000021229   ⟸   ENSPPAT00000044029
RefSeq Acc Id: ENSPPAP00000021221   ⟸   ENSPPAT00000044021
RefSeq Acc Id: ENSPPAP00000021223   ⟸   ENSPPAT00000044023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033825 Ensembl, ENTREZGENE
NCBI Gene DRD3 ENTREZGENE