SPOUT1 (SPOUT domain containing methyltransferase 1) - Rat Genome Database

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Gene: SPOUT1 (SPOUT domain containing methyltransferase 1) Pan paniscus
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Symbol: SPOUT1
Name: SPOUT domain containing methyltransferase 1
RGD ID: 11848735
Description: ENCODES a protein that exhibits miRNA binding (inferred); INVOLVED IN post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH genetic disease (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN kinetochore (inferred); mitotic spindle (inferred); spindle pole centrosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative methyltransferase C9orf114 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,518,731 - 10,529,032 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,521,078 - 10,531,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,945,345 - 99,953,692 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,612,741 - 128,620,510 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,613,437 - 128,620,450 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPOUT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,518,731 - 10,529,032 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,521,078 - 10,531,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,945,345 - 99,953,692 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,612,741 - 128,620,510 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,613,437 - 128,620,450 (-)Ensemblpanpan1.1panPan2
SPOUT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,819,651 - 128,829,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,819,651 - 128,829,794 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,581,930 - 131,592,073 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,624,166 - 130,631,906 (-)NCBINCBI36Build 36hg18NCBI36
Build 349128,663,898 - 128,671,639NCBI
Celera9102,235,130 - 102,242,872 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,190,929 - 101,201,101 (-)NCBIHuRef
CHM1_19131,732,931 - 131,743,102 (-)NCBICHM1_1
T2T-CHM13v2.09141,024,452 - 141,034,597 (-)NCBIT2T-CHM13v2.0
Spout1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,063,458 - 30,068,506 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,063,465 - 30,068,471 (-)EnsemblGRCm39 Ensembl
GRCm38230,173,446 - 30,178,494 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,173,453 - 30,178,459 (-)EnsemblGRCm38mm10GRCm38
MGSCv37230,028,967 - 30,033,975 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36229,995,482 - 30,000,464 (-)NCBIMGSCv36mm8
Celera229,877,319 - 29,882,327 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.29NCBI
Spout1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,849,007 - 33,856,564 (-)NCBIGRCr8
mRatBN7.2313,451,191 - 13,458,918 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,451,202 - 13,493,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,523,176 - 16,530,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.031,416,850 - 1,424,346 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,361,397 - 23,368,662 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,743,890 - 8,751,634 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,743,882 - 8,751,324 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,096,386 - 14,104,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,187,007 - 9,191,739 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera38,225,235 - 8,229,966 (-)NCBICelera
Cytogenetic Map3p12NCBI
Spout1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,204,040 - 1,211,020 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,202,987 - 1,211,052 (-)NCBIChiLan1.0ChiLan1.0
SPOUT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,802,145 - 54,811,709 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,802,214 - 54,810,039 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha953,997,645 - 54,005,543 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,723,175 - 55,731,078 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,723,229 - 55,731,078 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,483,818 - 54,491,711 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,796,597 - 54,804,479 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,889,984 - 54,897,891 (+)NCBIUU_Cfam_GSD_1.0
Spout1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,516,394 - 196,523,085 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,285,546 - 16,291,534 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,284,921 - 16,291,572 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPOUT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,157,176 - 269,167,087 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,157,173 - 269,167,154 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,173,218 - 303,183,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPOUT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,314,991 - 9,323,455 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666096153,700 - 162,161 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spout1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,186,901 - 6,196,374 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,186,779 - 6,193,519 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000001237   ⟹   ENSPPAP00000000348
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9128,613,437 - 128,620,450 (-)Ensembl
RefSeq Acc Id: XM_008975894   ⟹   XP_008974142
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,518,734 - 10,529,032 (+)NCBI
NHGRI_mPanPan1910,521,082 - 10,531,381 (+)NCBI
Mhudiblu_PPA_v0999,945,926 - 99,953,453 (-)NCBI
PanPan1.19128,612,741 - 128,620,510 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008975895   ⟹   XP_008974143
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,518,742 - 10,529,032 (+)NCBI
NHGRI_mPanPan1910,521,088 - 10,531,381 (+)NCBI
Mhudiblu_PPA_v0999,945,345 - 99,953,437 (-)NCBI
PanPan1.19128,612,741 - 128,620,509 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034929218   ⟹   XP_034785109
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,518,731 - 10,529,032 (+)NCBI
NHGRI_mPanPan1910,521,078 - 10,530,795 (+)NCBI
Mhudiblu_PPA_v0999,945,901 - 99,953,692 (-)NCBI
RefSeq Acc Id: XM_034929219   ⟹   XP_034785110
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21110,518,737 - 10,529,032 (+)NCBI
NHGRI_mPanPan1910,521,084 - 10,530,795 (+)NCBI
Mhudiblu_PPA_v0999,945,901 - 99,953,447 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008974142 (Get FASTA)   NCBI Sequence Viewer  
  XP_008974143 (Get FASTA)   NCBI Sequence Viewer  
  XP_034785109 (Get FASTA)   NCBI Sequence Viewer  
  XP_034785110 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000000348.1
RefSeq Acc Id: XP_008974142   ⟸   XM_008975894
- Peptide Label: isoform X3
- UniProtKB: A0A2R8Z6E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008974143   ⟸   XM_008975895
- Peptide Label: isoform X4
- UniProtKB: A0A2R8Z6E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034785109   ⟸   XM_034929218
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034785110   ⟸   XM_034929219
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000000348   ⟸   ENSPPAT00000001237


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000001094 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000001237.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  3.40.1280.10 UniProtKB/TrEMBL
InterPro Alpha/beta_knot_MTases UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Put_MeTrfase UniProtKB/TrEMBL
  tRNA_m1G_MTases_N UniProtKB/TrEMBL
NCBI Gene SPOUT1 ENTREZGENE
PANTHER METHYLTRANSFERASE C9ORF114-RELATED UniProtKB/TrEMBL
  PTHR12150 UniProtKB/TrEMBL
Pfam Methyltrn_RNA_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
  SSF75217 UniProtKB/TrEMBL
UniProt A0A2R8Z6E5 ENTREZGENE, UniProtKB/TrEMBL