HOOK1 (hook microtubule tethering protein 1) - Rat Genome Database

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Gene: HOOK1 (hook microtubule tethering protein 1) Pan paniscus
Analyze
Symbol: HOOK1
Name: hook microtubule tethering protein 1
RGD ID: 11847978
Description: ENCODES a protein that exhibits actin binding (inferred); dynein light intermediate chain binding (inferred); identical protein binding (inferred); INVOLVED IN cytoplasmic microtubule organization (ortholog); Golgi organization (ortholog); manchette assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); FOUND IN HOPS complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hook homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21166,976,173 - 167,037,934 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11166,127,368 - 166,188,994 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0159,072,565 - 59,134,191 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1160,777,771 - 60,839,384 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl160,777,769 - 60,839,384 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HOOK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21166,976,173 - 167,037,934 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11166,127,368 - 166,188,994 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0159,072,565 - 59,134,191 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1160,777,771 - 60,839,384 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl160,777,769 - 60,839,384 (+)Ensemblpanpan1.1panPan2
HOOK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38159,814,949 - 59,876,322 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl159,814,786 - 59,876,322 (+)EnsemblGRCh38hg38GRCh38
GRCh37160,280,621 - 60,341,994 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36160,053,121 - 60,114,638 (+)NCBINCBI36Build 36hg18NCBI36
Build 34159,992,553 - 60,050,663NCBI
Celera158,569,347 - 58,630,858 (+)NCBICelera
Cytogenetic Map1p32.1NCBI
HuRef158,391,575 - 58,453,086 (+)NCBIHuRef
CHM1_1160,396,048 - 60,457,518 (+)NCBICHM1_1
T2T-CHM13v2.0159,693,392 - 59,754,772 (+)NCBIT2T-CHM13v2.0
Hook1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39495,855,418 - 95,913,649 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl495,855,477 - 95,913,650 (+)EnsemblGRCm39 Ensembl
GRCm38495,967,181 - 96,025,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl495,967,240 - 96,025,413 (+)EnsemblGRCm38mm10GRCm38
MGSCv37495,634,070 - 95,690,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36495,459,397 - 95,516,295 (+)NCBIMGSCv36mm8
Celera494,347,244 - 94,404,130 (+)NCBICelera
Cytogenetic Map4C5NCBI
cM Map444.17NCBI
Hook1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85115,940,199 - 116,003,482 (+)NCBIGRCr8
mRatBN7.25110,824,501 - 110,887,791 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5110,824,501 - 110,887,787 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5113,398,070 - 113,461,456 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05115,123,588 - 115,186,837 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05115,186,126 - 115,249,371 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05114,940,053 - 115,000,691 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5114,940,053 - 115,000,691 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05118,887,278 - 118,948,329 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45116,324,845 - 116,397,148 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15116,330,192 - 116,401,230 (+)NCBI
Celera5109,429,863 - 109,492,144 (+)NCBICelera
Cytogenetic Map5q33NCBI
Hook1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546447,732 - 129,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546447,895 - 129,414 (-)NCBIChiLan1.0ChiLan1.0
HOOK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1549,994,930 - 50,060,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl549,998,241 - 50,060,525 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha550,061,824 - 50,127,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0550,174,930 - 50,240,548 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl550,151,823 - 50,240,588 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1550,126,351 - 50,191,713 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0550,071,546 - 50,137,133 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0550,354,297 - 50,419,906 (-)NCBIUU_Cfam_GSD_1.0
Hook1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505873,256,734 - 73,310,248 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365222,102,787 - 2,159,525 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOOK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16152,636,118 - 152,709,422 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26140,117,269 - 140,192,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOOK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12073,137,181 - 73,198,389 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2073,133,522 - 73,198,205 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603344,188,365 - 44,257,809 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hook1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624862544,156 - 593,919 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624862540,971 - 594,087 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000053686   ⟹   ENSPPAP00000030822
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl160,777,769 - 60,839,384 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053694   ⟹   ENSPPAP00000030830
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl160,780,327 - 60,835,964 (+)Ensembl
RefSeq Acc Id: XM_008977980   ⟹   XP_008976228
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21166,976,173 - 167,037,933 (-)NCBI
NHGRI_mPanPan11166,127,368 - 166,188,993 (-)NCBI
Mhudiblu_PPA_v0159,072,565 - 59,134,191 (+)NCBI
PanPan1.1160,777,771 - 60,839,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055092017   ⟹   XP_054947992
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21166,976,173 - 167,037,934 (-)NCBI
NHGRI_mPanPan11166,127,368 - 166,188,994 (-)NCBI
RefSeq Acc Id: XM_063600864   ⟹   XP_063456934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21166,976,173 - 167,030,837 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008976228 (Get FASTA)   NCBI Sequence Viewer  
  XP_054947992 (Get FASTA)   NCBI Sequence Viewer  
  XP_063456934 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000030822
  ENSPPAP00000030822.1
  ENSPPAP00000030830.1
Reference Protein Sequences
RefSeq Acc Id: XP_008976228   ⟸   XM_008977980
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BWC2 (UniProtKB/TrEMBL),   A0A2R9BMB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000030822   ⟸   ENSPPAT00000053686
RefSeq Acc Id: ENSPPAP00000030830   ⟸   ENSPPAT00000053694
RefSeq Acc Id: XP_054947992   ⟸   XM_055092017
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BWC2 (UniProtKB/TrEMBL),   A0A2R9BMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063456934   ⟸   XM_063600864
- Peptide Label: isoform X2
Protein Domains
Calponin-homology (CH)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038359 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053686.1 UniProtKB/TrEMBL
  ENSPPAT00000053694.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Hook_C UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
KEGG Report pps:100983581 UniProtKB/TrEMBL
NCBI Gene HOOK1 ENTREZGENE
PANTHER HOOK PROTEINS UniProtKB/TrEMBL
  PROTEIN HOOK HOMOLOG 1 UniProtKB/TrEMBL
Pfam HOOK UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
Superfamily-SCOP Hook domain UniProtKB/TrEMBL
UniProt A0A2R9BMB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BWC2 ENTREZGENE, UniProtKB/TrEMBL