SYAP1 (synapse associated protein 1)

Gene: SYAP1 (synapse associated protein 1) Pan paniscus

Analyze

Symbol:

SYAP1

Name:

synapse associated protein 1

RGD ID:

11846110

Description:

INVOLVED IN cellular response to epidermal growth factor stimulus (inferred); cellular response to insulin stimulus (inferred); cellular response to insulin-like growth factor stimulus (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN axon (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

synapse-associated protein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	18,513,953 - 18,559,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	18,517,355 - 18,563,264 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	9,339,052 - 9,384,940 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	16,706,612 - 16,747,610 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	16,706,612 - 16,747,610 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to epidermal growth factor stimulus (IEA)

cellular response to insulin stimulus (IEA)

cellular response to insulin-like growth factor stimulus (IEA)

cellular response to platelet-derived growth factor stimulus (IEA)

positive regulation of fat cell differentiation (IEA)

regulation of short-term neuronal synaptic plasticity (IEA)

TORC2 signaling (IEA)

Cellular Component

axon (IEA)

cytoplasmic side of plasma membrane (IEA)

cytosol (IEA)

dendrite (IEA)

Golgi apparatus (IEA)

growth cone (IEA)

nucleoplasm (IEA)

nucleus (IEA)

perikaryon (IEA)

perinuclear region of cytoplasm (IEA)

postsynaptic membrane (IEA)

presynaptic membrane (IEA)

synapse (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

SYAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	18,513,953 - 18,559,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	18,517,355 - 18,563,264 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	9,339,052 - 9,384,940 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	16,706,612 - 16,747,610 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	16,706,612 - 16,747,610 (+)	Ensembl	panpan1.1		panPan2

SYAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	16,719,612 - 16,765,340 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	16,719,612 - 16,765,340 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	16,737,735 - 16,783,463 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	16,647,676 - 16,689,274 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	16,497,411 - 16,538,990	NCBI
Celera	X	20,856,106 - 20,899,205 (+)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	14,492,402 - 14,537,626 (+)	NCBI		HuRef
CHM1_1	X	16,768,134 - 16,811,230 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	16,302,094 - 16,347,824 (+)	NCBI		T2T-CHM13v2.0

Syap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	161,639,839 - 161,671,458 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	161,640,053 - 161,671,443 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	162,856,843 - 162,888,462 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	162,857,057 - 162,888,447 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	159,294,775 - 159,326,394 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	158,200,957 - 158,232,536 (-)	NCBI		MGSCv36	mm8
Celera	X	146,080,878 - 146,112,325 (-)	NCBI		Celera
Cytogenetic Map	X	F4	NCBI
cM Map	X	75.06	NCBI

Syap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	35,423,947 - 35,458,472 (+)	NCBI		GRCr8
mRatBN7.2	X	31,792,180 - 31,826,672 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	31,792,193 - 31,826,667 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	32,826,576 - 32,860,973 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	36,262,037 - 36,296,470 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	32,450,970 - 32,485,371 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	33,528,071 - 33,562,584 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	33,528,081 - 33,562,589 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	33,875,296 - 33,909,818 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	52,547,035 - 52,580,729 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	52,600,503 - 52,634,197 (+)	NCBI
Celera	X	32,096,512 - 32,130,214 (+)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

Syap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955519	1,553,463 - 1,575,198 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955519	1,556,376 - 1,575,144 (-)	NCBI	ChiLan1.0	ChiLan1.0

SYAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	12,869,824 - 12,902,677 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	12,869,932 - 12,901,258 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	12,721,005 - 12,753,430 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	12,833,223 - 12,865,316 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	12,833,182 - 12,871,736 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	12,900,899 - 12,933,036 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	12,887,326 - 12,919,524 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	12,955,747 - 12,987,897 (+)	NCBI		UU_Cfam_GSD_1.0

Syap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	5,994,221 - 6,027,555 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	5,994,177 - 6,028,037 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	5,994,217 - 6,026,057 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SYAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	13,181,953 - 13,208,341 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	13,181,948 - 13,206,948 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	14,160,817 - 14,185,753 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SYAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	15,150,457 - 15,206,076 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	15,150,502 - 15,206,554 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	17,002,411 - 17,045,791 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Syap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	1,459,233 - 1,479,890 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	1,459,301 - 1,479,548 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003819524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000061899 ⟹ ENSPPAP00000038990

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	16,706,612 - 16,747,610 (+)	Ensembl

RefSeq Acc Id:

XM_003819524 ⟹ XP_003819572

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	18,513,953 - 18,559,863 (+)	NCBI
NHGRI_mPanPan1	X	18,517,355 - 18,563,264 (+)	NCBI
Mhudiblu_PPA_v0	X	9,339,052 - 9,384,940 (+)	NCBI
PanPan1.1	X	16,706,612 - 16,747,610 (+)	NCBI

Sequence:

show sequence

GCGGGGCTGCGGCGGCTGCGGTGTTCCTCCGACTTCCGGACATCTCCCTGGGAGTCGCGCAGAG
TGGAGTCAAAGGCAACCAGTGCTCGCTGCGGTCTCTGGGGATCGGGATCGCGGCGGCGGCCCCG
CGAGCGGGATGTTCCGGGGCTTGAGCAGTTGGTTGGGCTTGCAGCAGCCGGTGGCAGGCGGTGG
GCAGCCCATTGGAGATGCTCCACCCGAGCAGCGGTCCGAGACGGTGGCTGAGTCTGCGGAGGAG
GAGCTGCAGCAAGCGGGAGACCAGGAGCTCCTCCACCAGGCCAAAGACTTCGGCAACTATTTAT
TTAACTTTGCATCTGCTGCCACAAAAAAGATAACTGAATCAGTTGCTGAAACAGCACAAACAAT
AAAGAAATCCGTAGAAGAAGGAAAAATAGATGGCATCATTGACAAGACAATTATAGGAGATTTT
CAGAAGGAACAGAAAAAATTTGTTGAAGAGCAACATACAAAGAAGTCAGAAGCAGCTGTGCCCC
CATGGGTTGACACTAACGATGAAGAAACAATTCAACAACAAATTTTGGCCTTATCAGCTGACAA
GAGGAATTTCCTTCGTGACCCTCCGGCCGGCGTGCAATTTAATTTCGACTTTGATCAGATGTAC
CCCGTGGCCCTGGTCATGCTCCAGGAGGATGAGCTGCTAAGCAAGATGAGATTTGCCCTCGTTC
CTAAACTTGTGAAGGAAGAAGTGTTCTGGAGGAACTACTTTTACCGCGTCTCCCTGATTAAGCA
GTCAGCCCAGCTCACGGCCCTGGCTGCCCAACAGCAGGCCGCAGGGAAGGAGGAGAAGAGCAAT
GGCAGAGAGCAAGATTTGCCGCTGGCAGAGGCAGTACGGCCCAAAACGCCACCCGTTGTAATCA
AATCTCAGCTTAAAACTCAAGAGGATGAGGAAGAAATTTCTACTAGCCCAGGTGTTTCTGAGTT
TGTCAGTGATGCCTTCGATGCCTGTAACCTAAATCAGGAAGATCTAAGGAAAGAAATGGAGCAA
CTAGTGCTTGACAAAAAGCAAGAGGAGACAGCCGTACTGGAAGAGGATTCTGCAGATTGGGAAA
AAGAACTGCAGCAGGAACTTCAAGAATATGAAGTGGTGACAGAATCTGAAAAACGAGATGAAAA
CTGGGATAAGGAAATAGAGAAAATGCTTCAAGAGGAAAATTAGCTGTTCCTGAAATAGAAGAAT
AATCCTTAACAGTCTGCAAACTGACATTAAATTCTAGATGTTGACACTTACTGAATCAGAAGGC
ATGAAAGAGTATAATTTTATGAAATTCAAAATTATTCTTTTTTCAAGTTGAAACTTGCCTCTTC
TACTTTAAAAAAGTATATAGAACAGTTACTTCTAATAATCAGAAAGAGATGTTTTATAGAACAT
TTCTTTAATATAAAGTTAGAGATGTCTTCATAGGCAGTATGGCTATCTTTGCCACAGAAACATA
AGTAAAATTTTAGAGTTCTGTTTTCCATGAGGTCAAAAATATAATTTATTCCTCAGTCATGGTT
TTCTAAATATCTGTACTCCACATTCCATTTTAATTGATATGAGGGTGTTAAAGTACCTACTTAA
TGGGTTGATTACTATCAAAATGACCAAATATACCAAAGAACTTAAGAGGAAGCACTTTCAGAAC
TATTCACTTGCCAGGTATTTTCTAAAATTCCACCTGAAAGCCAAAAGATAAATAAGTTGATTTT
AATGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003819572	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000038990
	ENSPPAP00000038990.1

RefSeq Acc Id:

XP_003819572 ⟸ XM_003819524

- UniProtKB:

A0A2R9CAK3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFRGLSSWLGLQQPVAGGGQPIGDAPPEQRSETVAESAEEELQQAGDQELLHQAKDFGNYLFNF
ASAATKKITESVAETAQTIKKSVEEGKIDGIIDKTIIGDFQKEQKKFVEEQHTKKSEAAVPPWV
DTNDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSKMRFALVPKL
VKEEVFWRNYFYRVSLIKQSAQLTALAAQQQAAGKEEKSNGREQDLPLAEAVRPKTPPVVIKSQ
LKTQEDEEEISTSPGVSEFVSDAFDACNLNQEDLRKEMEQLVLDKKQEETAVLEEDSADWEKEL
QQELQEYEVVTESEKRDENWDKEIEKMLQEEN

hide sequence

RefSeq Acc Id:

ENSPPAP00000038990 ⟸ ENSPPAT00000061899

Protein Domains

BSD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042206	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000061899.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.3970.10	UniProtKB/TrEMBL
InterPro	BSD_dom	UniProtKB/TrEMBL
	BSD_dom_sf	UniProtKB/TrEMBL
KEGG Report	pps:100975342	UniProtKB/TrEMBL
NCBI Gene	SYAP1	ENTREZGENE
PANTHER	SYNAPSE-ASSOCIATED PROTEIN	UniProtKB/TrEMBL
	SYNAPSE-ASSOCIATED PROTEIN 1	UniProtKB/TrEMBL
Pfam	BSD	UniProtKB/TrEMBL
PROSITE	BSD	UniProtKB/TrEMBL
SMART	BSD	UniProtKB/TrEMBL
Superfamily-SCOP	SSF140383	UniProtKB/TrEMBL
UniProt	A0A2R9CAK3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar