DECR2 (2,4-dienoyl-CoA reductase 2) - Rat Genome Database

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Gene: DECR2 (2,4-dienoyl-CoA reductase 2) Pan paniscus
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Symbol: DECR2
Name: 2,4-dienoyl-CoA reductase 2
RGD ID: 11844961
Description: ENCODES a protein that exhibits 2,4-dienoyl-CoA reductase (NADPH) activity (ortholog); INVOLVED IN fatty acid catabolic process (inferred); fatty acid metabolic process (inferred); unsaturated fatty acid biosynthetic process (inferred); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 2,4-dienoyl-CoA reductase 2, peroxisomal; peroxisomal 2,4-dienoyl-CoA reductase; peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218631,096 - 642,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,420,568 - 4,430,821 (+)NCBINHGRI_mPanPan1
PanPan1.116395,041 - 406,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16395,158 - 405,928 (+)Ensemblpanpan1.1panPan2


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DECR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218631,096 - 642,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,420,568 - 4,430,821 (+)NCBINHGRI_mPanPan1
PanPan1.116395,041 - 406,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16395,158 - 405,928 (+)Ensemblpanpan1.1panPan2
DECR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816401,885 - 412,482 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16401,858 - 412,487 (+)EnsemblGRCh38hg38GRCh38
GRCh3716451,885 - 462,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616391,859 - 402,488 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416391,858 - 402,487NCBI
Celera16652,405 - 662,884 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16370,920 - 381,537 (+)NCBIHuRef
CHM1_116451,798 - 462,431 (+)NCBICHM1_1
T2T-CHM13v2.016398,130 - 408,668 (+)NCBIT2T-CHM13v2.0
Decr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,300,182 - 26,309,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,300,182 - 26,309,311 (-)EnsemblGRCm39 Ensembl
GRCm381726,081,208 - 26,090,322 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,081,208 - 26,090,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,218,156 - 26,227,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,808,811 - 25,817,764 (-)NCBIMGSCv36mm8
Celera1726,615,219 - 26,624,120 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.06NCBI
Decr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,609,389 - 15,617,779 (-)NCBIGRCr8
mRatBN7.21015,104,907 - 15,113,281 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,844,315 - 19,852,298 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,333,200 - 19,341,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,832,983 - 14,841,013 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,451,850 - 15,460,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,265,550 - 15,273,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,350,593 - 15,358,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,351,563 - 15,359,609 (-)NCBI
Celera1014,773,344 - 14,781,377 (-)NCBICelera
Cytogenetic Map10q12NCBI
Decr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,797,190 - 16,807,199 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,799,927 - 16,807,199 (-)NCBIChiLan1.0ChiLan1.0
DECR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,108,878 - 40,118,760 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,111,215 - 40,115,726 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,371,650 - 41,381,329 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,450,318 - 40,460,010 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,450,920 - 40,460,105 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1640,138,713 - 40,148,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,098,911 - 40,108,594 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,578,136 - 40,587,824 (-)NCBIUU_Cfam_GSD_1.0
Decr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,444,262 - 112,454,980 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501547,063 - 552,914 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501542,365 - 553,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DECR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,295,648 - 41,304,032 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,291,038 - 41,304,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,124,047 - 41,137,274 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DECR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15342,006 - 357,369 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5342,038 - 357,392 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,819,836 - 30,830,433 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Decr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,238,173 - 1,244,374 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,237,797 - 1,246,723 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000048259   ⟹   ENSPPAP00000025432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16395,158 - 405,928 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048264   ⟹   ENSPPAP00000025437
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16395,158 - 400,052 (+)Ensembl
RefSeq Acc Id: XM_034951545   ⟹   XP_034807436
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v218631,096 - 642,162 (+)NCBI
NHGRI_mPanPan1164,420,568 - 4,430,821 (+)NCBI
RefSeq Acc Id: XM_034951546   ⟹   XP_034807437
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v218631,097 - 642,162 (+)NCBI
NHGRI_mPanPan1164,420,568 - 4,430,821 (+)NCBI
RefSeq Acc Id: XM_034951547   ⟹   XP_034807438
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v218631,102 - 642,162 (+)NCBI
NHGRI_mPanPan1164,420,574 - 4,430,821 (+)NCBI
RefSeq Acc Id: XM_055099458   ⟹   XP_054955433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v218634,263 - 642,162 (+)NCBI
NHGRI_mPanPan1164,423,736 - 4,430,821 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034807436 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807437 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807438 (Get FASTA)   NCBI Sequence Viewer  
  XP_054955433 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025432.1
  ENSPPAP00000025437.1
RefSeq Acc Id: ENSPPAP00000025432   ⟸   ENSPPAT00000048259
RefSeq Acc Id: ENSPPAP00000025437   ⟸   ENSPPAT00000048264
RefSeq Acc Id: XP_034807437   ⟸   XM_034951546
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B762 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034807436   ⟸   XM_034951545
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B762 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034807438   ⟸   XM_034951547
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B762 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054955433   ⟸   XM_055099458
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035847 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048259.1 UniProtKB/TrEMBL
  ENSPPAT00000048264.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro DECR2-like UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene DECR2 ENTREZGENE
PANTHER PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] UniProtKB/TrEMBL
  PTHR43296 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  adh_short_C2 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A2R9B762 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B768_PANPA UniProtKB/TrEMBL