EXOSC2 (exosome component 2) - Rat Genome Database

Name: EXOSC2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: EXOSC2 (exosome component 2) Pan paniscus

Analyze

Symbol:

EXOSC2

Name:

exosome component 2

RGD ID:

11844351

Description:

ENCODES a protein that exhibits RNA exonuclease activity (ortholog); INVOLVED IN CUT catabolic process (inferred); exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (inferred); nuclear polyadenylation-dependent rRNA catabolic process (inferred); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2K (ortholog); citrullinemia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic exosome (RNase complex) (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

exosome complex component RRP4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EXOSC2 (exosome component 2)	NCBI	Ortholog
Mus musculus (house mouse):	Exosc2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Exosc2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Exosc2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EXOSC2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Exosc2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EXOSC2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EXOSC2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Exosc2 (exosome component 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	8,645,017 - 8,658,268 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	8,647,358 - 8,660,558 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	101,815,368 - 101,826,464 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	130,464,487 - 130,475,719 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	130,464,487 - 130,475,719 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive limb-girdle muscular dystrophy type 2K (ISO)

citrullinemia (ISO)

genetic disease (ISO)

Liver Neoplasms (ISO)

pre-malignant neoplasm (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

short stature, hearing loss, retinitis pigmentosa, and distinctive facies (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

CUT catabolic process (IEA)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IEA)

nuclear polyadenylation-dependent rRNA catabolic process (IEA)

obsolete exonucleolytic catabolism of deadenylated mRNA (IEA)

obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' (IEA)

poly(A)-dependent snoRNA 3'-end processing (IEA)

positive regulation of cell growth (IEA)

RNA catabolic process (IEA)

RNA processing (IEA)

rRNA processing (IEA)

TRAMP-dependent tRNA surveillance pathway (IEA)

U4 snRNA 3'-end processing (IEA)

Cellular Component

cytoplasm (IEA)

cytoplasmic exosome (RNase complex) (IEA)

cytosol (IEA)

exosome (RNase complex) (IEA)

nuclear exosome (RNase complex) (IEA)

nucleolus (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

protein binding (ISO)

RNA binding (IEA)

RNA exonuclease activity (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

EXOSC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	8,645,017 - 8,658,268 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	8,647,358 - 8,660,558 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	101,815,368 - 101,826,464 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	130,464,487 - 130,475,719 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	130,464,487 - 130,475,719 (+)	Ensembl	panpan1.1		panPan2

EXOSC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	130,693,760 - 130,704,894 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	130,693,721 - 130,707,288 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	133,569,147 - 133,580,281 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	132,558,998 - 132,570,077 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	130,598,730 - 130,609,808	NCBI
Celera	9	104,107,689 - 104,118,983 (+)	NCBI		Celera
Cytogenetic Map	9	q34.12	NCBI
HuRef	9	103,055,772 - 103,067,067 (+)	NCBI		HuRef
CHM1_1	9	133,718,191 - 133,729,489 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	142,898,712 - 142,909,846 (+)	NCBI		T2T-CHM13v2.0

Exosc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	31,560,727 - 31,571,593 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	31,560,727 - 31,571,361 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	31,670,715 - 31,681,352 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	31,670,715 - 31,681,349 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	31,526,257 - 31,536,840 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	31,492,745 - 31,503,329 (+)	NCBI		MGSCv36	mm8
Celera	2	31,371,398 - 31,381,973 (+)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	21.86	NCBI

Exosc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	35,360,652 - 35,370,948 (+)	NCBI		GRCr8
mRatBN7.2	3	14,962,930 - 14,973,645 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	14,962,917 - 14,973,575 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	18,036,215 - 18,046,468 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	26,621,221 - 26,631,474 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	24,868,310 - 24,878,557 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	10,151,734 - 10,161,997 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	10,151,284 - 10,161,989 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	15,511,096 - 15,521,359 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	10,786,985 - 10,797,248 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	10,683,157 - 10,693,688 (+)	NCBI
Celera	3	9,711,298 - 9,721,560 (+)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

Exosc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	639,731 - 651,418 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	639,798 - 648,360 (+)	NCBI	ChiLan1.0	ChiLan1.0

EXOSC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	53,266,396 - 53,276,236 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	53,266,401 - 53,276,677 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	52,464,948 - 52,475,561 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	54,165,433 - 54,176,045 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	54,166,710 - 54,176,018 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	52,942,940 - 52,953,572 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	53,263,746 - 53,274,359 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	53,356,968 - 53,367,401 (-)	NCBI		UU_Cfam_GSD_1.0

Exosc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	197,906,868 - 197,918,427 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	17,675,303 - 17,687,943 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	17,675,401 - 17,686,224 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EXOSC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	270,748,537 - 270,758,111 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	270,748,534 - 270,757,717 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	304,671,187 - 304,680,415 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EXOSC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	7,441,812 - 7,452,979 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	7,442,791 - 7,452,964 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	8,011,684 - 8,022,863 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Exosc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	5,035,663 - 5,044,549 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	5,036,185 - 5,044,504 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003822375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003822376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000046074 ⟹ ENSPPAP00000023252

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	9	130,464,487 - 130,475,719 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000046077 ⟹ ENSPPAP00000023255

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	9	130,464,487 - 130,475,719 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000046094 ⟹ ENSPPAP00000023272

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	9	130,464,525 - 130,474,626 (+)	Ensembl

RefSeq Acc Id:

XM_003822375 ⟹ XP_003822423

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	11	8,645,017 - 8,658,268 (-)	NCBI
NHGRI_mPanPan1	9	8,647,358 - 8,660,558 (-)	NCBI
Mhudiblu_PPA_v0	9	101,815,369 - 101,826,464 (+)	NCBI
PanPan1.1	9	130,464,487 - 130,475,719 (+)	NCBI

Sequence:

show sequence

CCGACTGAGCTGCGCCTGCGCAACTCATTGGCGCCAAGATGGCGATGGAGATGAGGCTTCCAGT
GGCTCGCAAGCCTCTTAGCGAGAGACTGGGCCGCGACACTAAGAAACATCTAGTGGTGCCGGGG
GATACAATCACTACGGACACAGGATTCATGCGGGGCCATGGAACGTATATGGGAGAAGAGAAGC
TCATTGCATCTGTTGCTGGCTCTGTGGAGAGAGTAAACAAGTTGATCTGTGTGAAAGCTTTGAA
AACCAGATACATTGGTGAAGTAGGAGACATCGTAGTGGGACGAATCACAGAGGTTCAACAGAAG
AGGTGGAAGGTGGAGACCAACTCCAGGCTGGATTCGGTCTTGCTGCTCTCGTCCATGAACCTTC
CTGGAGGAGAGCTGAGGAGAAGATCTGCAGAAGATGAGCTTGCAATGAGAGGTTTCTTACAGGA
AGGGGACCTTATCAGTGCTGAGGTCCAGGCAGTGTTCTCTGACGGAGCTGTCTCTTTGCACACG
AGGAGCCTGAAATATGGAAAACTAGGTCAGGGGGTTTTGGTCCAGGTTTCCCCCTCCCTGGTGA
AACGGCAGAAGACCCACTTTCATGATTTGCCATGTGGTGCCTCAGTGATTCTCGGTAACAACGG
CTTCATCTGGATTTACCCAACACCTGAGCACAAAGAAGAGGAAGCAGGGGGCTTCATTGCAAAC
CTGGAGCCTGTCTCTCTTGCTGATCGAGAGGTGATATCCCGGCTTCGGAACTGCATCATCTCTC
TGGTAACTCAGAGGATGATGCTGTATGATACCAGCATCCTGTACTGCTATGAAGCATCCCTTCC
ACATCAGATCAAAGACATCTTAAAGCCAGAAATAATGGAGGAGATTGTGATGGAAACACGCCAG
AGGCTTTTAGAACAGGAGGGATAAGGAGGTGCTCCAGAAGCACGGGACTGTGGACCTTGCAGGA
GTGAAGACTGTGATGTGTGGTCCCCATATGTGGCTCAGCGAAGACTCGAGAGATCATCCCTTTG
TCTGCCTTGACGGCCCTGTGACGGCCTCCAGCCCACAGGCCTGCTTTCTCCTGTCCTAACACCA
AGCCTGGGTGGCAGATGAACAGTGCTTCCTTGGGTTGCCAGCTGAGTCCCGGTATTAGGGAATA
GTTTCAGCTCTTTCAAAGTGCACAGTGTTACAGTCGAATGGGCTCCCATCCTGGAATAATATGG
AGAATCCTTTGTCTTCCACTCACTGTCATTCACAAGGCACAGTGCCCCATGAAATTGCCCCAAT
AGAAAACATGGCATCCCTGACCTCCAAATGGTCTGTTTTGGCCTCCATTCCTATATCCTTTAAA
TGACTGAGAATGCAGCTGGTAAAGTTGGAAGAATAAAGTTAACCAAGCAGGCCAGGCGCGGTGG
CTCACGCCTATAATCCCAGCACTTAGGGAGGGCAAGGCGGGCAGATCACCTGAGGTCAATAGTT
CGAGACCAGCCTGGCCAACAAGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGG
TGTGGTGGTGCGCACCTGTAGTCCCAGCTATTTGGGAGGCTGAGGTGGGAGAATCACTTGAACC
TGGGAGGCGGAGGTTGCAGTGAGCTGAAATCGCGTATCGCACTCCCGCCTGGGTGACAGAGCGA
GACTCTGTTTCAAAGAAAAAAAAACAAGCAGCCTTTTGCTTGGTTGGAATCTGATTTTCTGTTG
CGTGTTCCTTGTAGCCATAGATGTGATTATGTCCACACCGGGCTGCCTTAATCTGTCCTGCTTG
GAGAGTGACTTGTAAGATGCTGAATTATTCATGATAATAGAGTGAATGTTCTGGGTCCATGTAC
TCAGATAAACATGAAGAAAATAAGCTGAGAAAAATGGAGACTGGAAAAGCAAAGCTGTTTTCGT
CCTATAATTGAAGTAGTGTGGAGCATTAACTTGTGGATAATTCAGAGTTAAAAGATAAAAAGAC
GCCAGAGTTCTCGCTGAAGAATGTGAGAA

hide sequence

RefSeq Acc Id:

XM_003822376 ⟹ XP_003822424

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	11	8,645,017 - 8,658,215 (-)	NCBI
NHGRI_mPanPan1	9	8,647,358 - 8,660,558 (-)	NCBI
Mhudiblu_PPA_v0	9	101,815,368 - 101,826,461 (+)	NCBI
PanPan1.1	9	130,464,487 - 130,475,719 (+)	NCBI

Sequence:

show sequence

CCGACTGAGCTGCGCCTGCGCAACTCATTGGCGCCAAGATGGCGATGGAGATGAGGCTTCCAGT
GGCTCGCAAGCCTCTTAGCGAGAGACTGGGCCGCGACACTAAGAAACATCTAGTGGTGCCGGGG
GATACAATCACTACGGACACAGGATTCATGCGGGGCCATGGAACGTATATGGGAGAAGAGAAGC
TCATTGCATCTGTTGCTGGCTCTGTGGAGAGAGTAAACAAGTTGATCTGTGTGAAAGCTTTGAA
AACCAGATACATTGGTGAAGTAGGAGACATCGTAGTGGGACGAATCACAGAGGTTCAACAGAAG
AGGTGGAAGGTGGAGACCAACTCCAGGCTGGATTCGGTCTTGCTGCTCTCGTCCATGAACCTTC
CTGGAGGAGAGCTGAGGAGAAGATCTGCAGAAGATGAGCTTGCAATGAGAGGTTTCTTACAGGA
AGGGGACCTTATCAGTGGGGTTTTGGTCCAGGTTTCCCCCTCCCTGGTGAAACGGCAGAAGACC
CACTTTCATGATTTGCCATGTGGTGCCTCAGTGATTCTCGGTAACAACGGCTTCATCTGGATTT
ACCCAACACCTGAGCACAAAGAAGAGGAAGCAGGGGGCTTCATTGCAAACCTGGAGCCTGTCTC
TCTTGCTGATCGAGAGGTGATATCCCGGCTTCGGAACTGCATCATCTCTCTGGTAACTCAGAGG
ATGATGCTGTATGATACCAGCATCCTGTACTGCTATGAAGCATCCCTTCCACATCAGATCAAAG
ACATCTTAAAGCCAGAAATAATGGAGGAGATTGTGATGGAAACACGCCAGAGGCTTTTAGAACA
GGAGGGATAAGGAGGTGCTCCAGAAGCACGGGACTGTGGACCTTGCAGGAGTGAAGACTGTGAT
GTGTGGTCCCCATATGTGGCTCAGCGAAGACTCGAGAGATCATCCCTTTGTCTGCCTTGACGGC
CCTGTGACGGCCTCCAGCCCACAGGCCTGCTTTCTCCTGTCCTAACACCAAGCCTGGGTGGCAG
ATGAACAGTGCTTCCTTGGGTTGCCAGCTGAGTCCCGGTATTAGGGAATAGTTTCAGCTCTTTC
AAAGTGCACAGTGTTACAGTCGAATGGGCTCCCATCCTGGAATAATATGGAGAATCCTTTGTCT
TCCACTCACTGTCATTCACAAGGCACAGTGCCCCATGAAATTGCCCCAATAGAAAACATGGCAT
CCCTGACCTCCAAATGGTCTGTTTTGGCCTCCATTCCTATATCCTTTAAATGACTGAGAATGCA
GCTGGTAAAGTTGGAAGAATAAAGTTAACCAAGCAGGCCAGGCGCGGTGGCTCACGCCTATAAT
CCCAGCACTTAGGGAGGGCAAGGCGGGCAGATCACCTGAGGTCAATAGTTCGAGACCAGCCTGG
CCAACAAGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGGTGTGGTGGTGCGCA
CCTGTAGTCCCAGCTATTTGGGAGGCTGAGGTGGGAGAATCACTTGAACCTGGGAGGCGGAGGT
TGCAGTGAGCTGAAATCGCGTATCGCACTCCCGCCTGGGTGACAGAGCGAGACTCTGTTTCAAA
GAAAAAAAAACAAGCAGCCTTTTGCTTGGTTGGAATCTGATTTTCTGTTGCGTGTTCCTTGTAG
CCATAGATGTGATTATGTCCACACCGGGCTGCCTTAATCTGTCCTGCTTGGAGAGTGACTTGTA
AGATGCTGAATTATTCATGATAATAGAGTGAATGTTCTGGGTCCATGTACTCAGATAAACATGA
AGAAAATAAGCTGAGAAAAATGGAGACTGGAAAAGCAAAGCTGTTTTCGTCCTATAATTGAAGT
AGTGTGGAGCATTAACTTGTGGATAATTCAGAGTTAAAAGATAAAAAGACGCCAGAGTTCTCGC
TGAAGAATGTGAGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003822423	(Get FASTA)	NCBI Sequence Viewer
	XP_003822424	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000023252
	ENSPPAP00000023252.1
	ENSPPAP00000023255
	ENSPPAP00000023255.1
	ENSPPAP00000023272.1

RefSeq Acc Id:	XP_003822423 ⟸ XM_003822375
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9B7H9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVN KLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE LAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCG ASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSI LYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG hide sequence

RefSeq Acc Id:	XP_003822424 ⟸ XM_003822376
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9B0Y2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVN KLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE LAMRGFLQEGDLISGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGG FIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVM ETRQRLLEQEG hide sequence

RefSeq Acc Id:

ENSPPAP00000023252 ⟸ ENSPPAT00000046074

RefSeq Acc Id:

ENSPPAP00000023255 ⟸ ENSPPAT00000046077

RefSeq Acc Id:

ENSPPAP00000023272 ⟸ ENSPPAT00000046094

Protein Domains

Exosome complex component N-terminal K Homology RRP4 S1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034796	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000046074.1	UniProtKB/TrEMBL
	ENSPPAT00000046077.1	UniProtKB/TrEMBL
	ENSPPAT00000046094.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.100	UniProtKB/TrEMBL
	2.40.50.140	UniProtKB/TrEMBL
InterPro	Exosome_cplx_N_dom	UniProtKB/TrEMBL
	Exosome_RNA_bind1/RRP40/RRP4	UniProtKB/TrEMBL
	KH_dom_type_1	UniProtKB/TrEMBL
	KH_dom_type_1_sf	UniProtKB/TrEMBL
	NA-bd_OB-fold	UniProtKB/TrEMBL
	RRP4_S1	UniProtKB/TrEMBL
KEGG Report	pps:100994305	UniProtKB/TrEMBL
NCBI Gene	EXOSC2	ENTREZGENE
PANTHER	EXOSOME COMPLEX COMPONENT RRP4	UniProtKB/TrEMBL
	PTHR21321	UniProtKB/TrEMBL
Pfam	ECR1_N	UniProtKB/TrEMBL
	KH_6	UniProtKB/TrEMBL
	RRP4_S1	UniProtKB/TrEMBL
Superfamily-SCOP	Ribosomal L27 protein-like	UniProtKB/TrEMBL
	SSF50249	UniProtKB/TrEMBL
	SSF54791	UniProtKB/TrEMBL
UniProt	A0A2R9B0Y2	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B7H9	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B7J6_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM