MRPL15 (mitochondrial ribosomal protein L15)

Gene: MRPL15 (mitochondrial ribosomal protein L15) Pan paniscus

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Symbol:

MRPL15

Name:

mitochondrial ribosomal protein L15

RGD ID:

11841854

Description:

ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN large ribosomal subunit (inferred); mitochondrial large ribosomal subunit (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

39S ribosomal protein L15, mitochondrial; large ribosomal subunit protein uL15m

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	69,771,654 - 69,784,720 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	45,496,597 - 45,509,681 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	50,560,420 - 50,573,049 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	47,936,446 - 47,948,584 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	47,935,643 - 47,948,584 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (IEA,ISO)

translation (IEA)

Cellular Component

large ribosomal subunit (IEA)

mitochondrial large ribosomal subunit (IEA)

mitochondrion (IEA)

ribonucleoprotein complex (IEA)

ribosome (IEA)

Molecular Function

protein binding (ISO)

structural constituent of ribosome (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MRPL15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	69,771,654 - 69,784,720 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	45,496,597 - 45,509,681 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	50,560,420 - 50,573,049 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	47,936,446 - 47,948,584 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	47,935,643 - 47,948,584 (+)	Ensembl	panpan1.1		panPan2

MRPL15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	54,135,241 - 54,148,514 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	54,135,241 - 54,148,514 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	55,047,801 - 55,061,074 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	55,210,334 - 55,223,014 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	55,210,333 - 55,223,011	NCBI
Celera	8	51,038,346 - 51,051,638 (+)	NCBI		Celera
Cytogenetic Map	8	q11.23	NCBI
HuRef	8	50,515,702 - 50,528,983 (+)	NCBI		HuRef
CHM1_1	8	55,099,593 - 55,112,890 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	54,512,543 - 54,525,817 (+)	NCBI		T2T-CHM13v2.0

Mrpl15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	4,843,432 - 4,855,949 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	4,843,429 - 4,855,962 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	4,773,198 - 4,785,750 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	4,773,206 - 4,785,739 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	4,763,279 - 4,775,807 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	4,763,290 - 4,775,791 (-)	NCBI		MGSCv36	mm8
Celera	1	4,785,037 - 4,797,586 (-)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.79	NCBI

Mrpl15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	19,527,745 - 19,539,061 (+)	NCBI		GRCr8
mRatBN7.2	5	14,729,961 - 14,741,276 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	14,729,979 - 14,741,276 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	16,924,207 - 16,935,288 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	18,537,717 - 18,548,790 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	18,258,877 - 18,269,950 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	14,609,656 - 14,620,965 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	14,609,674 - 14,620,965 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	19,392,153 - 19,403,455 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	14,932,623 - 14,943,904 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	14,932,590 - 14,941,120 (+)	NCBI
Celera	5	14,101,085 - 14,112,172 (+)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

Mrpl15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	13,398,478 - 13,406,794 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	13,398,479 - 13,404,353 (+)	NCBI	ChiLan1.0	ChiLan1.0

MRPL15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	5,704,572 - 5,711,577 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	5,704,585 - 5,711,567 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	6,079,400 - 6,086,416 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	5,780,690 - 5,787,722 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	5,780,733 - 5,788,498 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	5,717,373 - 5,724,399 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	5,922,950 - 5,929,947 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	6,006,201 - 6,013,221 (+)	NCBI		UU_Cfam_GSD_1.0

Mrpl15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	73,787,265 - 73,799,049 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	986,131 - 1,001,648 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	986,442 - 997,440 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRPL15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	77,069,092 - 77,083,723 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	77,069,074 - 77,083,595 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	84,142,552 - 84,149,289 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRPL15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	50,201,805 - 50,214,534 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	50,201,829 - 50,216,206 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	91,720,535 - 91,733,740 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrpl15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	1,564,789 - 1,573,311 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	1,565,627 - 1,572,471 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003823243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000044839 ⟹ ENSPPAP00000022034

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	47,935,643 - 47,948,584 (+)	Ensembl

RefSeq Acc Id:

XM_003823243 ⟹ XP_003823291

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	69,771,654 - 69,784,720 (+)	NCBI
NHGRI_mPanPan1	8	45,496,597 - 45,509,681 (+)	NCBI
Mhudiblu_PPA_v0	8	50,560,420 - 50,573,049 (+)	NCBI
PanPan1.1	8	47,936,446 - 47,948,584 (+)	NCBI

Sequence:

show sequence

ACAAAGCAGCCCCCGAGACCACGTGGCCTCCGAGCAGCTCAGGGCGCCCTTGAAAGTTCTTGGA
TCTGCGGGTTATGGCCGGTCCCTTGCAGGGCGGTGGGGTCCGGGCCCTGGACCTACTCCGGGGC
CTGCCGCGTGTGAGCCTGGCCAACTTAAAGCCGAATCCCGGCTCCAAGAAACCGGAGAGAAGAC
CAAGAGGTCGGAGAAGAGGTAGAAAATGTGGCAGAGGCCATAAAGGAGAAAGGCAAAGAGGAAC
CCGGCCCCGCTTGGGCTTTGAGGGAGGCCAGACTCCATTTTACATCCGAATCCCAAAATACGGG
TTTAACGAAGGACATAGTTTCAGACGCCAGTATAAGCCTTTGAGTCTCAATAGACTGCAGTATC
TTATTGATTTGGGTCGTGTTGATCCTAGTCAACCTATTGACTTAACCCAGCTTGTCAATGGGAG
AGGTGTGACCATCCAGCCACTTAAAAGGGATTATGGTGTCCAGCTGGTTGAGGAGGGTGCTGAC
ACCTTTACGGCGAAAGTTAATATTGAAGTACAGTTGGCTTCAGAACTAGCTATTGCTGCCATTG
AAAAAAATGGTGGTGTTGTTACTACAGCCTTCTATGATCCAAGAAGTCTGGACATTGTATGCAA
ACCTGTTCCATTCTTTCTTCGTGGACAACCCATTCCAAAAAGAATGCTTCCACCAGAAGAACTG
GTACCATATTACACTGATGCAAAGAACCGTGGGTACCTGGCGGATCCTGCCAAATTTCCTGAAG
CACGACTTGAACTCGCCAGGAAGTATGGTTATATCTTACCTGATATCACTAAAGATGAACTCTT
CAAAATGCTCTGTACTAGGAAGGATCCAAGGCAGATTTTCTTTGGTCTTGCTCCAGGATGGGTG
GTGAATATGGCCGATAAGAAAATCCTAAAACCTACAGATGAAAATCTCCTTAAGTATTATACCT
CATGAATTCCCGCCCAAGGAAGCAGAGTTGTTAAAGAGTACTGGAATAGGGGCTGAAGGATCTA
TATTCCCTCATTGCATTTTCCTTATGTATAATTTTCCAGATGGTGATGTTACTTTTCAGTGTAC
TCATATGTCTCATTTTCATCTAAAATTAAATGGCAGGAAACAAGGACTGCATAGAGAAACTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003823291	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022034.1

RefSeq Acc Id:

XP_003823291 ⟸ XM_003823243

- UniProtKB:

A0A2R9AXT2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGPLQGGGVRALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQRGTRPR
LGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGRVDPSQPIDLTQLVNGRGVT
IQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVP
FFLRGQPIPKRMLPPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKML
CTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS

hide sequence

RefSeq Acc Id:

ENSPPAP00000022034 ⟸ ENSPPAT00000044839

Protein Domains

Large ribosomal subunit protein uL15/eL18

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034223	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000044839.1	UniProtKB/TrEMBL
Gene3D-CATH	3.100.10.10	UniProtKB/TrEMBL
InterPro	L18e/L15P_sf	UniProtKB/TrEMBL
	Ribosomal_L15	UniProtKB/TrEMBL
	Ribosomal_L15_bac-type	UniProtKB/TrEMBL
	Ribosomal_L18e/L15P	UniProtKB/TrEMBL
KEGG Report	pps:100970004	UniProtKB/TrEMBL
NCBI Gene	MRPL15	ENTREZGENE
PANTHER	39S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR12934	UniProtKB/TrEMBL
Pfam	Ribosomal_L27A	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52080	UniProtKB/TrEMBL
UniProt	A0A2R9AXT2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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