POLR3D (RNA polymerase III subunit D)

Gene: POLR3D (RNA polymerase III subunit D) Pan paniscus

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Symbol:

POLR3D

Name:

RNA polymerase III subunit D

RGD ID:

11837761

Description:

ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of interferon-beta production (inferred); transcription by RNA polymerase III (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH Conotruncal Cardiac Defects (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DNA-directed RNA polymerase III subunit RPC4; polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	40,744,924 - 40,752,918 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	16,470,123 - 16,478,117 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	21,489,492 - 21,499,948 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	18,429,013 - 18,435,060 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,429,013 - 18,435,060 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Conotruncal Cardiac Defects (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of innate immune response (IEA)

positive regulation of interferon-beta production (IEA)

transcription by RNA polymerase III (IEA)

tRNA transcription by RNA polymerase III (IEA)

Cellular Component

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

RNA polymerase III complex (IEA)

Molecular Function

chromatin binding (IEA)

DNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase III transcription pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

POLR3D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	40,744,924 - 40,752,918 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	16,470,123 - 16,478,117 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	21,489,492 - 21,499,948 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	18,429,013 - 18,435,060 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,429,013 - 18,435,060 (+)	Ensembl	panpan1.1		panPan2

POLR3D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	22,245,133 - 22,254,601 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	22,245,133 - 22,254,601 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	22,102,646 - 22,112,114 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	22,158,564 - 22,164,625 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	22,158,563 - 22,164,624	NCBI
Celera	8	21,064,952 - 21,071,014 (+)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	20,644,813 - 20,650,874 (+)	NCBI		HuRef
CHM1_1	8	22,304,282 - 22,310,343 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	22,519,087 - 22,528,555 (+)	NCBI		T2T-CHM13v2.0

Polr3d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	70,676,188 - 70,680,911 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	70,676,197 - 70,680,887 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	70,438,748 - 70,443,471 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	70,438,757 - 70,443,447 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,838,555 - 70,843,278 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	69,173,876 - 69,178,527 (-)	NCBI		MGSCv36	mm8
Celera	14	67,980,237 - 67,984,960 (-)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.32	NCBI

Polr3d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,921,283 - 51,925,952 (-)	NCBI		GRCr8
mRatBN7.2	15	45,511,587 - 45,516,256 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,511,589 - 45,516,353 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,629,449 - 49,634,118 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,740,946 - 50,745,615 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	47,600,253 - 47,604,922 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	52,129,471 - 52,134,140 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,129,471 - 52,134,140 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,852,988 - 55,857,657 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,838,153 - 50,842,822 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,854,526 - 50,858,347 (-)	NCBI
Celera	15	45,190,713 - 45,195,382 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

Polr3d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	45,721,266 - 45,727,214 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	45,721,266 - 45,727,214 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLR3D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	35,011,189 - 35,016,617 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	35,011,861 - 35,016,605 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	35,599,339 - 35,606,355 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	35,221,091 - 35,228,107 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	35,220,227 - 35,228,098 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	35,166,570 - 35,173,586 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	35,021,103 - 35,028,122 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	35,176,601 - 35,183,620 (-)	NCBI		UU_Cfam_GSD_1.0

Polr3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	12,513,348 - 12,519,015 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	6,051,476 - 6,057,164 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	6,051,528 - 6,057,165 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR3D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,521,024 - 6,532,156 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,520,962 - 6,529,526 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	6,955,056 - 6,963,574 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR3D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	20,314,020 - 20,320,118 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	20,314,081 - 20,319,455 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	21,916,062 - 21,922,148 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr3d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	17,817,690 - 17,824,427 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	17,817,716 - 17,823,442 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003823600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000035501 ⟹ ENSPPAP00000012834

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	18,429,013 - 18,435,060 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000035506 ⟹ ENSPPAP00000012839

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	18,429,353 - 18,432,386 (+)	Ensembl

RefSeq Acc Id:

XM_003823600 ⟹ XP_003823648

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	40,744,924 - 40,752,918 (+)	NCBI
NHGRI_mPanPan1	8	16,470,123 - 16,478,117 (+)	NCBI
Mhudiblu_PPA_v0	8	21,489,492 - 21,499,948 (+)	NCBI
PanPan1.1	8	18,429,013 - 18,435,060 (+)	NCBI

Sequence:

show sequence

GCGGCGCCCAGGCCCTGCCACGCAGACTTCCGCCCGGCGCGGAGACCGAAGGCTGGCGGCGGGT
CGCGTTGCAGGCAACATGTCGGAAGGAAACGCCGCCGGCGAGCCCAGCACGCCGGGAGGGCCCC
GACCTCTCCTGACTGGGGCCCGGGGGCTCATCGGGCGGCGGCCGGCGCCTCCCCTCACCCCCGG
CCGCCTTCCCTCCATCCGTTCCAGGGACCTCACCCTCGGGGGAGTCAAGAAGAAAACCTTCACC
CCAAATATCATCAGTCGGAAGATCAAGGAAGAGCCCAAGGAAGAAGTAACTGTCAAGAAGGAGA
AGCGTGAAAGGGACAGAGACCGACAACGAGAGGGGCATGGACGAGGGCGAGGCCGTCCAGAAGT
GATCCAGTCTCACTCCATCTTTGAGCAGGGCCCAGCCGAAATGATGAAGAAAAAAGGGAACTGG
GATAAGACAGTGGATGTGTCAGACATGGGACCTTCTCATATCATCAACATCAAAAAAGAGAAGA
GAGAGACAGACGAAGAAACTAAACAGATCTTGCGTATGCTGGAGAAGGACGATTTCCTCGATGA
CCCCGGCCTGAGGAACGACACTCGAAATATGCCTGTGCAGCTGCCGCTGGCTCACTCAGGATGG
CTTTTTAAGGAAGAAAATGACGAACCAGATGTTAAACCTTGGCTGGCTGGCCCCAAGGAAGAGG
ACATGGAGGTGGACATACCTGCTGTGAAAGTGAAAGAGGAGCCACGAGATGAGGAGGAAGAGGC
CAAGATGAAGGCTCCTCCCAAAGCAGCCAGGAAGACTCCAGGCCTCCCGAAGGATGTATCTGTG
GCAGAGCTGCTGAGGGAGCTGAGCCTCACCAAGGAAGAGGAACTGCTGTTTCTGCAGCTGCCAG
ACACCCTCCCTGGCCAGCCACCCACCCAGGACATCAAGCCTATCAAGACAGAGGTGCAGGGCGA
GGACGGACAGGTGGTGCTCATCAAGCAGGAGAAAGACCGAGAAGCCAAGTTGGCAGAGAATGCT
TGTACCCTGGCTGACCTGACAGAGGGTCAGGTTGGCAAGCTACTCATCCGCAAGTCTGGAAGGG
TGCAACTCCTCCTGGGCAAGGTGACTCTGGACGTGACCATGGGAACTGCCTGCTCCTTCCTGCA
GGAGCTGGTGTCCGTGAGCCTTGGAGACAGTAGGACAGGGGAGATGACAGTCCTGGGACACGTG
AAGCACAAACTTGTATGTTCCCCTGATTTTGAATCTCTCTTGGATCACAAACACCGGTAAAATG
AGCAGATGGAGGAGGACGGCGCCTGTGCCCACGGCTGCTGCCTGCTTCAGACATTTTGTTCTTG
AATCTGTGAGACCCAGAAGGGGCCCACTGAGCCCACTCACTCCAGCCTTTGGCAGCCATTGTTC
CAGGTCCCCCAGGGCTTCCTCCCACAGCAGCTGTGAATGGCACAGTGACCTTCCTGCAGCGTGG
AGATGGCACATCCTTGCTGCTGGGGACTTGGCCCTGCTATTTATTTTTGTATTTATGTCTTAAT
CTCTTCCACTGATGCATCCTCTAAGGGTAGATGGGGAGGGTCTGTGTGAAGGGGCTGGCTTCTT
TTGGTGCCTGCTGGGTTGCAGGGGCAGGAAGCGTGTGGACTGCAGCTTCTGCTGGTGCTCCCCC
CTTCCTCCTGGAGGCAGTATAGGAGAGAGAGCAAGGATTGAGTCTGAGACTTAAGCACTCGGTC
CCAGCTTGCCAGTTCCTGGTTCTGTGTCCTTGGACAAACTACCTAACCTTTCTGAGCCTCCTAT
ACCTCATCCGACACAAATGGGGATGATACCTACCTCCAGGGTTGGTGTGAGGATTCATGGGCTA
TTATAGATGAAAACTGCACAAGGCCAGAACCAGCAGGCACTCAATAAACGTTCATGTCCTTTTT
CTCTA

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Protein Sequences


Protein RefSeqs	XP_003823648	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000012834.1
	ENSPPAP00000012839.1

RefSeq Acc Id:

XP_003823648 ⟸ XM_003823600

- UniProtKB:

A0A2R9A6A7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEGNAAGEPSTPGGPRPLLTGARGLIGRRPAPPLTPGRLPSIRSRDLTLGGVKKKTFTPNIIS
RKIKEEPKEEVTVKKEKRERDRDRQREGHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVD
VSDMGPSHIINIKKEKRETDEETKQILRMLEKDDFLDDPGLRNDTRNMPVQLPLAHSGWLFKEE
NDEPDVKPWLAGPKEEDMEVDIPAVKVKEEPRDEEEEAKMKAPPKAARKTPGLPKDVSVAELLR
ELSLTKEEELLFLQLPDTLPGQPPTQDIKPIKTEVQGEDGQVVLIKQEKDREAKLAENACTLAD
LTEGQVGKLLIRKSGRVQLLLGKVTLDVTMGTACSFLQELVSVSLGDSRTGEMTVLGHVKHKLV
CSPDFESLLDHKHR

hide sequence

RefSeq Acc Id:

ENSPPAP00000012839 ⟸ ENSPPAT00000035506

RefSeq Acc Id:

ENSPPAP00000012834 ⟸ ENSPPAT00000035501

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000029591	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000035501.1	UniProtKB/TrEMBL
	ENSPPAT00000035506.1	UniProtKB/TrEMBL
InterPro	RPC4	UniProtKB/TrEMBL
KEGG Report	pps:100978060	UniProtKB/TrEMBL
NCBI Gene	POLR3D	ENTREZGENE
PANTHER	DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4	UniProtKB/TrEMBL
	PTHR13408	UniProtKB/TrEMBL
Pfam	RNA_pol_Rpc4	UniProtKB/TrEMBL
UniProt	A0A2R9A6A7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A6B5_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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