SGPP1 (sphingosine-1-phosphate phosphatase 1) - Rat Genome Database

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Gene: SGPP1 (sphingosine-1-phosphate phosphatase 1) Pan paniscus
Analyze
Symbol: SGPP1
Name: sphingosine-1-phosphate phosphatase 1
RGD ID: 11836083
Description: ENCODES a protein that exhibits sphingosine-1-phosphate phosphatase activity (inferred); INVOLVED IN ER to Golgi ceramide transport (ortholog); extrinsic apoptotic signaling pathway (ortholog); intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN actin cytoskeleton (ortholog); Golgi apparatus (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01444,265,017 - 44,308,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11462,521,010 - 62,566,309 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SGPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01444,265,017 - 44,308,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11462,521,010 - 62,566,309 (-)NCBIpanpan1.1PanPan1.1panPan2
SGPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381463,684,216 - 63,728,065 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1463,684,216 - 63,728,065 (-)EnsemblGRCh38hg38GRCh38
GRCh371464,150,934 - 64,194,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361463,220,687 - 63,264,509 (-)NCBINCBI36Build 36hg18NCBI36
Build 341463,220,688 - 63,264,509NCBI
Celera1444,201,594 - 44,245,417 (-)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1444,317,325 - 44,361,142 (-)NCBIHuRef
CHM1_11464,089,953 - 64,133,737 (-)NCBICHM1_1
T2T-CHM13v2.01457,891,616 - 57,935,465 (-)NCBIT2T-CHM13v2.0
Sgpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391275,761,022 - 75,782,503 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1275,761,023 - 75,782,503 (-)EnsemblGRCm39 Ensembl
GRCm381275,714,248 - 75,735,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1275,714,249 - 75,735,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv371276,815,235 - 76,836,716 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361276,633,105 - 76,654,502 (-)NCBIMGSCv36mm8
Celera1276,819,194 - 76,840,277 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1232.95NCBI
Sgpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86100,161,024 - 100,182,214 (-)NCBIGRCr8
mRatBN7.2694,425,339 - 94,446,534 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl694,425,339 - 94,446,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx694,818,696 - 94,839,851 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0695,117,168 - 95,138,323 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0694,546,078 - 94,567,225 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0698,675,324 - 98,696,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl698,675,326 - 98,695,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06108,093,013 - 108,114,339 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4698,306,168 - 98,327,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1698,311,877 - 98,330,264 (-)NCBI
Celera692,851,441 - 92,872,597 (-)NCBICelera
Cytogenetic Map6q24NCBI
Sgpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554666,075,507 - 6,103,739 (+)NCBIChiLan1.0ChiLan1.0
SGPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1838,195,649 - 38,228,299 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl838,197,532 - 38,228,406 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha837,888,039 - 37,921,345 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0838,422,209 - 38,455,539 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl838,422,214 - 38,455,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1838,038,844 - 38,072,143 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0838,111,070 - 38,144,393 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0838,471,314 - 38,504,624 (-)NCBIUU_Cfam_GSD_1.0
Sgpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864066,663,173 - 66,690,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364957,502,859 - 7,528,515 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364957,500,991 - 7,528,520 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1194,352,001 - 194,380,907 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11194,351,971 - 194,380,910 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21216,298,626 - 216,383,691 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12440,885,464 - 40,926,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2440,885,276 - 40,926,937 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605329,080,236 - 29,121,462 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473437,297,806 - 37,335,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473437,297,954 - 37,337,830 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_034937674   ⟹   XP_034793565
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBI
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBI
Mhudiblu_PPA_v01444,265,017 - 44,308,896 (-)NCBI
RefSeq Acc Id: XM_034937676   ⟹   XP_034793567
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBI
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBI
Mhudiblu_PPA_v01444,265,017 - 44,308,897 (-)NCBI
RefSeq Acc Id: XM_055097684   ⟹   XP_054953659
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBI
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034793565 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793567 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953659 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038157.1
  ENSPPAP00000038160.1
  ENSPPAP00000038164.1
  ENSPPAP00000038166.1
Reference Protein Sequences
RefSeq Acc Id: XP_034793567   ⟸   XM_034937676
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034793565   ⟸   XM_034937674
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054953659   ⟸   XM_055097684
- Peptide Label: isoform X1
Protein Domains
Phosphatidic acid phosphatase type 2/haloperoxidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041791 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061060.1 UniProtKB/TrEMBL
  ENSPPAT00000061063.1 UniProtKB/TrEMBL
  ENSPPAT00000061067.1 UniProtKB/TrEMBL
  ENSPPAT00000061069.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/TrEMBL
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/TrEMBL
NCBI Gene SGPP1 ENTREZGENE
PANTHER SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 UniProtKB/TrEMBL
  SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/TrEMBL
SMART acidPPc UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/TrEMBL
UniProt A0A2R9C890_PANPA UniProtKB/TrEMBL
  A0A2R9C896_PANPA UniProtKB/TrEMBL
  A0A2R9C8L4_PANPA UniProtKB/TrEMBL
  A0A2R9CIZ0_PANPA UniProtKB/TrEMBL