PLEKHH3 (pleckstrin homology, MyTH4 and FERM domain containing H3) - Rat Genome Database

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Gene: PLEKHH3 (pleckstrin homology, MyTH4 and FERM domain containing H3) Pan paniscus
Analyze
Symbol: PLEKHH3
Name: pleckstrin homology, MyTH4 and FERM domain containing H3
RGD ID: 11833704
Description: INVOLVED IN signal transduction (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family H member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,308,012 - 22,317,095 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,198,014 - 24,207,352 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,640,115 - 14,649,223 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,864,374 - 14,873,284 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,864,857 - 14,873,076 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoskeleton  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PLEKHH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,308,012 - 22,317,095 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,198,014 - 24,207,352 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,640,115 - 14,649,223 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,864,374 - 14,873,284 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,864,857 - 14,873,076 (+)Ensemblpanpan1.1panPan2
PLEKHH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,667,914 - 42,676,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,667,914 - 42,676,994 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,819,932 - 40,829,012 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,073,458 - 38,082,495 (-)NCBINCBI36Build 36hg18NCBI36
Celera1737,475,397 - 37,484,507 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,584,959 - 36,594,114 (-)NCBIHuRef
CHM1_11741,055,686 - 41,064,687 (-)NCBICHM1_1
T2T-CHM13v2.01743,525,053 - 43,534,132 (-)NCBIT2T-CHM13v2.0
Plekhh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,053,505 - 101,062,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,053,505 - 101,062,177 (-)EnsemblGRCm39 Ensembl
GRCm3811101,162,679 - 101,171,378 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,162,679 - 101,171,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,023,993 - 101,032,616 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,978,769 - 100,987,392 (-)NCBIMGSCv36mm8
Celera11112,458,780 - 112,467,423 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1164.32NCBI
Plekhh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,598,749 - 86,607,482 (-)NCBIGRCr8
mRatBN7.21086,098,461 - 86,106,931 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,098,469 - 86,106,880 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,134,865 - 91,143,291 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,613,705 - 90,622,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,006,862 - 86,015,277 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,076,467 - 89,084,952 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,076,472 - 89,084,885 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,874,963 - 88,883,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,183,689 - 90,192,105 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,198,058 - 90,206,442 (-)NCBI
Celera1084,816,035 - 84,824,454 (-)NCBICelera
Cytogenetic Map10q31NCBI
Plekhh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,524,017 - 16,531,440 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,523,822 - 16,531,563 (-)NCBIChiLan1.0ChiLan1.0
PLEKHH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,313,325 - 20,321,141 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,313,191 - 20,321,142 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,774,626 - 19,783,084 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,031,706 - 21,040,165 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,032,163 - 21,040,134 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,817,626 - 19,826,081 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,082,806 - 20,091,257 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,186,825 - 20,195,283 (+)NCBIUU_Cfam_GSD_1.0
Plekhh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,667,292 - 19,676,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,397,493 - 17,407,908 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,398,926 - 17,407,848 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,159,773 - 20,170,776 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,162,075 - 20,170,809 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,364,945 - 20,374,488 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,612,527 - 63,621,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,612,989 - 63,624,694 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,405,629 - 34,414,413 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhh3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247951,486,452 - 1,494,073 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000032074   ⟹   ENSPPAP00000009431
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1714,864,857 - 14,873,076 (+)Ensembl
RefSeq Acc Id: XM_003813901   ⟹   XP_003813949
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,308,012 - 22,317,095 (+)NCBI
NHGRI_mPanPan11724,198,015 - 24,207,351 (+)NCBI
Mhudiblu_PPA_v01714,640,118 - 14,649,223 (+)NCBI
PanPan1.11714,864,374 - 14,873,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034941816   ⟹   XP_034797707
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,308,012 - 22,317,095 (+)NCBI
NHGRI_mPanPan11724,198,015 - 24,207,351 (+)NCBI
Mhudiblu_PPA_v01714,640,421 - 14,647,510 (+)NCBI
RefSeq Acc Id: XM_055101177   ⟹   XP_054957152
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,309,521 - 22,317,095 (+)NCBI
NHGRI_mPanPan11724,199,942 - 24,207,352 (+)NCBI
RefSeq Acc Id: XM_063599029   ⟹   XP_063455099
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,308,030 - 22,317,095 (+)NCBI
RefSeq Acc Id: XM_063599030   ⟹   XP_063455100
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,308,030 - 22,315,586 (+)NCBI
RefSeq Acc Id: XM_063599031   ⟹   XP_063455101
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,308,030 - 22,315,586 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003813949   ⟸   XM_003813901
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZWT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034797707   ⟸   XM_034941816
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000009431   ⟸   ENSPPAT00000032074
RefSeq Acc Id: XP_054957152   ⟸   XM_055101177
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063455099   ⟸   XM_063599029
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063455100   ⟸   XM_063599030
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063455101   ⟸   XM_063599031
- Peptide Label: isoform X6
Protein Domains
MyTH4   PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027950 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032074.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  MyTH4_dom UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  RA_dom UniProtKB/TrEMBL
NCBI Gene PLEKHH3 ENTREZGENE
PANTHER AGAP003327-PA UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 UniProtKB/TrEMBL
Pfam MyTH4 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
PROSITE MYTH4 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
UniProt A0A2R8ZWT3 ENTREZGENE, UniProtKB/TrEMBL