REV1 (REV1 DNA directed polymerase) - Rat Genome Database

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Gene: REV1 (REV1 DNA directed polymerase) Pan paniscus
Analyze
Symbol: REV1
Name: REV1 DNA directed polymerase
RGD ID: 11833326
Description: ENCODES a protein that exhibits damaged DNA binding (inferred); deoxycytidyl transferase activity (inferred); DNA binding (inferred); INVOLVED IN error-prone translesion synthesis (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA repair protein REV1; REV1, DNA directed polymerase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21228,941,164 - 29,030,665 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A28,943,931 - 29,033,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,808,519 - 99,897,989 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A100,329,475 - 100,418,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A100,329,475 - 100,418,678 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
REV1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21228,941,164 - 29,030,665 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A28,943,931 - 29,033,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,808,519 - 99,897,989 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A100,329,475 - 100,418,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A100,329,475 - 100,418,678 (-)Ensemblpanpan1.1panPan2
REV1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38299,400,477 - 99,490,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl299,400,475 - 99,490,035 (-)EnsemblGRCh38hg38GRCh38
GRCh372100,016,940 - 100,106,479 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36299,383,370 - 99,472,912 (-)NCBINCBI36Build 36hg18NCBI36
Build 34299,475,931 - 99,564,998NCBI
Celera294,221,622 - 94,311,168 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef293,782,782 - 93,847,070 (-)NCBIHuRef
CHM1_12100,021,704 - 100,109,885 (-)NCBICHM1_1
T2T-CHM13v2.0299,859,127 - 99,948,858 (-)NCBIT2T-CHM13v2.0
Rev1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39138,091,867 - 38,169,191 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl138,091,867 - 38,168,882 (-)EnsemblGRCm39 Ensembl
GRCm38138,052,786 - 38,129,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl138,052,786 - 38,129,801 (-)EnsemblGRCm38mm10GRCm38
MGSCv37138,109,631 - 38,186,507 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,997,332 - 38,074,208 (-)NCBIMGSCv36mm8
Celera137,830,205 - 37,907,067 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map116.46NCBI
Rev1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,773,907 - 47,847,554 (-)NCBIGRCr8
mRatBN7.2940,278,100 - 40,351,764 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl940,278,101 - 40,351,576 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,773,815 - 48,846,572 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,896,577 - 53,969,330 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0952,178,823 - 52,252,241 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0944,714,137 - 44,786,330 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl944,714,386 - 44,786,041 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0944,410,205 - 44,481,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,994,269 - 37,042,663 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,995,974 - 37,069,555 (-)NCBI
Celera938,030,447 - 38,078,175 (-)NCBICelera
Cytogenetic Map9q21NCBI
Rev1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554705,677,222 - 5,738,362 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554705,677,222 - 5,738,362 (-)NCBIChiLan1.0ChiLan1.0
REV1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11043,150,885 - 43,247,324 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1042,586,394 - 43,247,328 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1043,074,777 - 43,171,213 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,020,399 - 44,116,914 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,020,389 - 44,116,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11043,733,744 - 43,830,134 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,016,125 - 44,112,521 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01044,198,477 - 44,294,929 (+)NCBIUU_Cfam_GSD_1.0
Rev1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629285,171,516 - 85,246,570 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366611,333,577 - 1,398,227 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366611,322,907 - 1,397,990 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REV1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1143,128,824 - 3,218,894 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl143,129,529 - 3,218,866 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041170,730,018 - 170,820,108 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rev1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247494,372,256 - 4,453,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247494,374,345 - 4,453,374 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038577   ⟹   ENSPPAP00000015884
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A100,329,475 - 100,418,678 (-)Ensembl
RefSeq Acc Id: XM_003805400   ⟹   XP_003805448
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,941,164 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,943,932 - 29,033,425 (+)NCBI
Mhudiblu_PPA_v02A99,808,519 - 99,897,989 (+)NCBI
PanPan1.12A100,329,475 - 100,418,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008970912   ⟹   XP_008969160
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,941,173 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,943,932 - 29,033,425 (+)NCBI
Mhudiblu_PPA_v02A99,808,519 - 99,897,989 (+)NCBI
PanPan1.12A100,329,475 - 100,418,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008970918   ⟹   XP_008969166
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,968,587 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,971,347 - 29,033,425 (+)NCBI
Mhudiblu_PPA_v02A99,835,932 - 99,897,989 (+)NCBI
PanPan1.12A100,329,475 - 100,391,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034953664   ⟹   XP_034809555
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,941,179 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,943,937 - 29,033,425 (+)NCBI
Mhudiblu_PPA_v02A99,808,525 - 99,897,989 (+)NCBI
RefSeq Acc Id: XM_034953665   ⟹   XP_034809556
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,966,225 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,943,931 - 29,033,425 (+)NCBI
Mhudiblu_PPA_v02A99,808,519 - 99,897,989 (+)NCBI
RefSeq Acc Id: XM_055107608   ⟹   XP_054963583
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,941,173 - 29,030,665 (+)NCBI
NHGRI_mPanPan12A28,943,932 - 29,033,425 (+)NCBI
RefSeq Acc Id: XM_063594770   ⟹   XP_063450840
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,999,213 - 29,030,665 (+)NCBI
RefSeq Acc Id: XM_063594772   ⟹   XP_063450842
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21228,999,213 - 29,030,665 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008969160   ⟸   XM_008970912
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003805448   ⟸   XM_003805400
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ALL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008969166   ⟸   XM_008970918
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_034809556   ⟸   XM_034953665
- Peptide Label: isoform X6
RefSeq Acc Id: XP_034809555   ⟸   XM_034953664
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000015884   ⟸   ENSPPAT00000038577
RefSeq Acc Id: XP_054963583   ⟸   XM_055107608
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063450842   ⟸   XM_063594772
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063450840   ⟸   XM_063594770
- Peptide Label: isoform X5
Protein Domains
BRCT   UmuC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038577.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.1280 UniProtKB/TrEMBL
  3.30.1490.100 UniProtKB/TrEMBL
  3.30.70.270 UniProtKB/TrEMBL
  3.40.1170.60 UniProtKB/TrEMBL
  3.40.50.10190 UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
  6.10.250.1490 UniProtKB/TrEMBL
  6.10.250.1630 UniProtKB/TrEMBL
InterPro BRCT_dom UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  DNA/RNA_pol_sf UniProtKB/TrEMBL
  DNA_pol_Y-fam_lit_finger_sf UniProtKB/TrEMBL
  DNA_pol_Y-fam_little_finger UniProtKB/TrEMBL
  HUWE1/Rev1_UBM UniProtKB/TrEMBL
  REV1 UniProtKB/TrEMBL
  Rev1_C UniProtKB/TrEMBL
  Rev1_C_sf UniProtKB/TrEMBL
  Rev1_UBM1/2 UniProtKB/TrEMBL
  Rev_trsase/Diguanyl_cyclase UniProtKB/TrEMBL
  UmuC UniProtKB/TrEMBL
KEGG Report pps:100977480 UniProtKB/TrEMBL
NCBI Gene REV1 ENTREZGENE
PANTHER DNA REPAIR PROTEIN REV1 UniProtKB/TrEMBL
  DNA REPAIR PROTEIN REV1 UniProtKB/TrEMBL
Pfam BRCT UniProtKB/TrEMBL
  IMS UniProtKB/TrEMBL
  IMS_C UniProtKB/TrEMBL
  POLH-Rev1_HhH UniProtKB/TrEMBL
  REV1_C UniProtKB/TrEMBL
  UBM UniProtKB/TrEMBL
PIRSF REV1 UniProtKB/TrEMBL
PROSITE BRCT UniProtKB/TrEMBL
  UMUC UniProtKB/TrEMBL
SMART BRCT UniProtKB/TrEMBL
Superfamily-SCOP SSF100879 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
  SSF56672 UniProtKB/TrEMBL
UniProt A0A2R9ALL6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 REV1  REV1 DNA directed polymerase    REV1, DNA directed polymerase  Symbol and/or name change 5135510 APPROVED