LOC100969372 (chymotrypsin like elastase 3A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: LOC100969372 (chymotrypsin like elastase 3A) Pan paniscus
Analyze
Symbol: LOC100969372 (Ensembl: CELA3A)
Name: chymotrypsin like elastase 3A
RGD ID: 11832254
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); congenital disorder of glycosylation Ir (ortholog); genetic disease (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CELA3A; chymotrypsin like elastase family member 3A; chymotrypsin-like elastase family member 3A
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21204,925,427 - 204,940,045 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11204,039,043 - 204,051,869 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0121,194,719 - 21,203,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,134,429 - 22,146,330 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,134,563 - 22,146,330 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100969372
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21204,925,427 - 204,940,045 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11204,039,043 - 204,051,869 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0121,194,719 - 21,203,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,134,429 - 22,146,330 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,134,563 - 22,146,330 (+)Ensemblpanpan1.1panPan2
CELA3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,001,657 - 22,012,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,001,657 - 22,012,542 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,328,150 - 22,339,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,200,736 - 22,211,622 (+)NCBINCBI36Build 36hg18NCBI36
Build 34122,073,454 - 22,084,339NCBI
Celera120,651,145 - 20,662,036 (+)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef120,572,006 - 20,582,899 (+)NCBIHuRef
CHM1_1122,440,682 - 22,450,845 (+)NCBICHM1_1
T2T-CHM13v2.0121,825,474 - 21,836,366 (+)NCBIT2T-CHM13v2.0
Cela3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,128,865 - 137,137,102 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4137,128,865 - 137,137,102 (-)EnsemblGRCm39 Ensembl
GRCm384137,401,554 - 137,409,791 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,401,554 - 137,409,791 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,957,469 - 136,965,706 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364136,674,383 - 136,681,845 (-)NCBIMGSCv36mm8
MGSCv364135,005,243 - 135,012,707 (-)NCBIMGSCv36mm8
Celera4135,615,979 - 135,624,292 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.88NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_063606528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000046578   ⟹   ENSPPAP00000023753
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl122,134,563 - 22,142,246 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000046579   ⟹   ENSPPAP00000023754
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl122,141,893 - 22,146,330 (+)Ensembl
RefSeq Acc Id: XM_063606528   ⟹   XP_063462598
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21204,925,427 - 204,940,045 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063462598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023753.1
  ENSPPAP00000023754.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000023754   ⟸   ENSPPAT00000046579
RefSeq Acc Id: ENSPPAP00000023753   ⟸   ENSPPAT00000046578
RefSeq Acc Id: XP_063462598   ⟸   XM_063606528
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035035 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046578.1 UniProtKB/TrEMBL
  ENSPPAT00000046579.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene LOC100969372 ENTREZGENE
PANTHER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER UniProtKB/TrEMBL
  CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3A UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A2R9B2I2_PANPA UniProtKB/TrEMBL
  A0A2R9B944_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 LOC100969372  chymotrypsin like elastase 3A  CELA3A  chymotrypsin like elastase 3A  Symbol and/or name change 5135510 APPROVED
2019-03-19 CELA3A  chymotrypsin like elastase 3A    chymotrypsin like elastase family member 3A  Symbol and/or name change 5135510 APPROVED
2018-05-08 CELA3A  chymotrypsin like elastase family member 3A  LOC100969372  chymotrypsin-like elastase family member 3A  Symbol and/or name change 5135510 APPROVED