CLDN7 (claudin 7) - Rat Genome Database

Name: CLDN7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: CLDN7 (claudin 7) Pan paniscus

Analyze

Symbol:

CLDN7

Name:

claudin 7

RGD ID:

11831240

Description:

ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of cell adhesion (ortholog); negative regulation of protein-containing complex assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); dyskeratosis congenita (ortholog); Neoplasm Metastasis (ortholog); FOUND IN apicolateral plasma membrane (ortholog); basolateral plasma membrane (ortholog); bicellular tight junction (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

claudin-7

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CLDN7 (claudin 7)	NCBI	Ortholog
Mus musculus (house mouse):	Cldn7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cldn7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cldn7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CLDN7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cldn7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CLDN7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	CLDN7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cldn7 (claudin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	7,277,313 - 7,281,859 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,277,313 - 7,281,859 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	7,289,766 - 7,292,433 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

dyskeratosis congenita (ISO)

Neoplasm Metastasis (ISO)

Prostatic Neoplasms (ISO)

Weissenbacher-Zweymuller syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of apoptotic process (ISO)

negative regulation of cell adhesion (ISO)

negative regulation of protein-containing complex assembly (ISO)

positive regulation of cell motility (ISO)

positive regulation of cell population proliferation (ISO)

response to ethanol (ISO)

Cellular Component

apicolateral plasma membrane (ISO)

basolateral plasma membrane (ISO)

bicellular tight junction (ISO)

lateral plasma membrane (ISO)

plasma membrane (ISO)

Molecular Function

cell adhesion molecule binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

References

Genomics

Comparative Map Data

CLDN7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	7,277,313 - 7,281,859 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,277,313 - 7,281,859 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	7,289,766 - 7,292,433 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

CLDN7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	17	7,259,903 - 7,263,983 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	17	7,259,903 - 7,263,213 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	17	7,163,222 - 7,166,532 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,103,946 - 7,106,519 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	17	7,104,183 - 7,106,513	NCBI
Celera	17	7,187,867 - 7,191,157 (-)	NCBI
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,054,628 - 7,057,918 (-)	NCBI		HuRef
CHM1_1	17	7,172,020 - 7,175,309 (-)	NCBI		CHM1_1

Cldn7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,855,605 - 69,858,712 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	11	69,855,605 - 69,858,711 (+)	Ensembl
GRCm38	11	69,964,779 - 69,967,886 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,964,779 - 69,967,885 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,779,003 - 69,781,380 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	69,781,696 - 69,784,073 (+)	NCBI			mm8
Celera	11	77,513,435 - 77,515,812 (+)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI

Cldn7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	54,689,684 - 54,692,177 (+)	NCBI
Rnor_6.0 Ensembl	10	56,576,428 - 56,578,626 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	10	56,576,326 - 56,578,632 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	56,321,522 - 56,323,751 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,810,947 - 56,813,134 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	56,825,014 - 56,826,754 (+)	NCBI
Celera	10	53,843,619 - 53,845,806 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Cldn7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	9,652,093 - 9,654,291 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	9,652,093 - 9,654,291 (+)	NCBI	ChiLan1.0	ChiLan1.0

CLDN7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	5	32,224,040 - 32,226,168 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	5	32,223,985 - 32,225,795 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Cldn7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936595	550,359 - 552,214 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLDN7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,612,507 - 52,628,362 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,612,517 - 52,628,376 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	54,822,459 - 54,828,675 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CLDN7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	6,632,695 - 6,635,994 (-)	NCBI
ChlSab1.1 Ensembl	16	6,630,412 - 6,635,327 (-)	Ensembl

Cldn7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	9,873,555 - 9,875,743 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008962464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000046847 ⟹ ENSPPAP00000024022

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	7,277,313 - 7,281,859 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000046849 ⟹ ENSPPAP00000024024

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	7,277,894 - 7,280,699 (-)	Ensembl

RefSeq Acc Id:

XM_008962464 ⟹ XP_008960712

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1	17	7,277,313 - 7,281,237 (-)	NCBI
Mhudiblu_PPA_v0	17	7,289,766 - 7,292,433 (-)	NCBI

Sequence:

show sequence

ATCCTCGGCCGCCTCTCCGGTCCCGCCTCCCCCTCCCGCGCTCCCGGGGCGCGCGGGCCGCGCC
CCCGACGTCCTACATATACTCAGGGTCGCCGAGAGCGCCCGGGGGGAACCGCCTGGCCTTCGGG
GACCACCGCTTTTGTCTGGAACCACCCTCCCGGCGTATCCTACTCCCTCTGCCGCGAGGCCATC
GCTTCACTGGAGGGGTCGATTTGTGTGTAGTTTGGTGACAAGATTTGCATTCACCTGGCCCAAA
CCCTTTTTGTCTCTTTGGGTGACCGGAAAACTCCACCTCAAATTTTCTTTTGTGGGGCTGCCCC
CCAAGTGTCGTTTGTTTTACTGTAGGGTCTCCCGCCCGGCGTCCCCAGTGTTTTCTGAGGGCGG
AAATGGCCAATTCGGGCCTGCAGTTGCTGGGCTTCTCCATGGCCCTGCTGGGCTGGGTGGGTCT
GGTGGCCTGCACCGCCATCCCGCAGTGGCAGATGAGCTCCTATGCGGGTGACAACATCATCACG
GCCCAGGCCATGTACAAGGGGCTGTGGATGGACTGCGTTACGCAGAGCACGGGGATGATGAGCT
GCAAAATGTACGACTCGGTGCTCGCCCTGTCCGCGGCCTTGCAGGCCACTCGAGCCCTAATGGT
GGTCTCCCTGGTGCTGGGCTTCCTGGCCATGTTTGTGGCCACGATGGGCATGAAGTGCACGCGC
TGTGGGGGAGACGACAAAGTGAAGAAGGCCCGTATAGCCATGGGTGGAGGCATAATTTTCATCG
TGGCAGGTCTTGCCGCCTTGGTAGCTTGCTCCTGGTATGGCCATCAGATTGTCACAGACTTTTA
TAACCCTTTGATCCCTACCAACATTAAGTATGAGTTTGGCCCTGCCATCTTTATTGGCTGGGCA
GGGTCTGCCCTAGTCATCCTGGGAGGTGCACTGCTCTCCTGTTCCTGTCCTGGGAATGAGAGCA
AGGCTGGGTACCGTGCACCCCGCTCTTACCCTAAGTCCAACTCTTCCAAGGAGTATGTGTGACC
TGGGATCTCCTTGCCCCAGCCTGACAGGCTATGGGAGTGTCTAGATGCCTGAAAGGGCCTGGGG
CTGAGCTCAGCCTGTGGGCAGGGTGCCGGACAAAGGCCTCCTGGTCACTCTGTCCCTGCACTCC
ATGTATAGTCCTCTTGGGTTGGGGCGGGGGTGCTGTTGGTGGGAGAGACAAAAAGAGGGAGAGT
GTGCTTTTTGTACAGTAATAAAAAATAAGTATTGGGAAGCAGGCTTTTTTCCCTTCAGGGCCTC
TGCTTTCCTCCCGTCCAGATCCTTGCAGGGAGCTTGGAACCTTAGTGCACCTACTTCAGTTCAG
AACACTTAGCACCCCACTGACTGCATTGACAATTGACTAAAAGATGCAGGTGCTCATATCTCGA
CATCCATTCCCACCCCCCTCTTATTTAAATAGCTACCAAAGTACTTCTTTTTTAATAAAAAAAT
AAAGATTTTTATTAGGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008960712	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_008960712 ⟸ XM_008962464

- Sequence:

show sequence

MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC
KMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIV
AGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESK
AGYRAPRSYPKSNSSKEYV

hide sequence

RefSeq Acc Id:

ENSPPAP00000024024 ⟸ ENSPPAT00000046849

RefSeq Acc Id:

ENSPPAP00000024022 ⟸ ENSPPAT00000046847

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000035150	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000024022	UniProtKB/TrEMBL
	ENSPPAP00000024024	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000046847	UniProtKB/TrEMBL
	ENSPPAT00000046849	UniProtKB/TrEMBL
InterPro	Claudin	UniProtKB/TrEMBL
	Claudin7	UniProtKB/TrEMBL
	Claudin_CS	UniProtKB/TrEMBL
	PMP22/EMP/MP20/Claudin	UniProtKB/TrEMBL
KEGG Report	pps:100989187	UniProtKB/TrEMBL
NCBI Gene	CLDN7	ENTREZGENE
PANTHER	PTHR12002	UniProtKB/TrEMBL
Pfam	PMP22_Claudin	UniProtKB/TrEMBL
PRINTS	CLAUDIN7	UniProtKB/TrEMBL
PROSITE	CLAUDIN	UniProtKB/TrEMBL
UniProt	A0A2R9B348_PANPA	UniProtKB/TrEMBL
	A0A2R9B9V0_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD