PPP4R3A (protein phosphatase 4 regulatory subunit 3A) - Rat Genome Database

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Gene: PPP4R3A (protein phosphatase 4 regulatory subunit 3A) Pan paniscus
Analyze
Symbol: PPP4R3A
Name: protein phosphatase 4 regulatory subunit 3A
RGD ID: 11830951
Description: ENCODES a protein that exhibits protein phosphatase activator activity (inferred); INVOLVED IN gluconeogenesis (ortholog); positive regulation of gluconeogenesis (ortholog); ASSOCIATED WITH achondrogenesis type IA (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1, suppressor of mek1; SMEK1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,607,630 - 92,663,099 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11491,823,988 - 91,879,617 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,083,948 - 72,137,158 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,429,512 - 91,481,006 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PPP4R3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,607,630 - 92,663,099 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11491,823,988 - 91,879,617 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,083,948 - 72,137,158 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,429,512 - 91,481,006 (-)NCBIpanpan1.1PanPan1.1panPan2
PPP4R3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381491,457,508 - 91,510,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1491,457,508 - 91,510,554 (-)EnsemblGRCh38hg38GRCh38
GRCh371491,923,852 - 91,976,898 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,993,708 - 91,046,397 (-)NCBINCBI36Build 36hg18NCBI36
Celera1471,972,721 - 72,025,463 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,100,431 - 72,153,269 (-)NCBIHuRef
CHM1_11491,862,107 - 91,914,785 (-)NCBICHM1_1
T2T-CHM13v2.01485,682,749 - 85,735,802 (-)NCBIT2T-CHM13v2.0
Ppp4r3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912101,005,668 - 101,051,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12101,005,668 - 101,049,961 (-)EnsemblGRCm39 Ensembl
GRCm3812101,039,409 - 101,083,737 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12101,039,409 - 101,083,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712102,277,619 - 102,321,912 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612101,440,568 - 101,484,450 (-)NCBIMGSCv36mm8
Celera12102,266,439 - 102,310,731 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.17NCBI
Ppp4r3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,032,068 - 126,098,329 (-)NCBIGRCr8
mRatBN7.26120,302,508 - 120,365,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,302,511 - 120,365,891 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6120,457,500 - 120,499,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06120,754,202 - 120,796,180 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,089,044 - 120,131,024 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,040,803 - 125,083,496 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,040,803 - 125,060,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06134,260,318 - 134,303,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46125,329,321 - 125,354,083 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16125,315,498 - 125,358,904 (-)NCBI
Celera6117,830,409 - 117,872,995 (-)NCBICelera
Cytogenetic Map6q32NCBI
Ppp4r3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543813,729,949 - 13,769,189 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543813,731,900 - 13,769,189 (-)NCBIChiLan1.0ChiLan1.0
PPP4R3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1862,304,805 - 62,344,232 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl862,305,947 - 62,344,147 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha861,882,231 - 61,921,384 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0862,575,974 - 62,615,348 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl862,576,504 - 62,615,274 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1862,255,227 - 62,294,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0862,306,118 - 62,345,243 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0862,635,753 - 62,675,109 (-)NCBIUU_Cfam_GSD_1.0
Ppp4r3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,601,609 - 13,645,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648818,422,741 - 18,467,430 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648818,423,353 - 18,467,363 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP4R3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,111,332 - 113,148,954 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17113,111,305 - 113,148,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27119,663,267 - 119,700,061 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP4R3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12469,219,313 - 69,270,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2469,218,583 - 69,270,929 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605356,469,945 - 56,521,712 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp4r3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473411,160,356 - 11,197,817 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473411,160,253 - 11,197,264 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_034938022   ⟹   XP_034793913
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21592,607,630 - 92,660,684 (-)NCBI
NHGRI_mPanPan11491,823,988 - 91,876,657 (-)NCBI
Mhudiblu_PPA_v01472,083,985 - 72,136,624 (-)NCBI
RefSeq Acc Id: XM_034938023   ⟹   XP_034793914
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21592,607,630 - 92,660,754 (-)NCBI
NHGRI_mPanPan11491,823,988 - 91,879,617 (-)NCBI
Mhudiblu_PPA_v01472,083,948 - 72,137,158 (-)NCBI
RefSeq Acc Id: XM_055097948   ⟹   XP_054953923
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21592,607,630 - 92,660,727 (-)NCBI
NHGRI_mPanPan11491,823,988 - 91,877,236 (-)NCBI
RefSeq Acc Id: XM_055097949   ⟹   XP_054953924
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21592,607,630 - 92,663,099 (-)NCBI
NHGRI_mPanPan11491,823,988 - 91,879,617 (-)NCBI
RefSeq Acc Id: XM_055097950   ⟹   XP_054953925
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21592,607,630 - 92,663,099 (-)NCBI
NHGRI_mPanPan11491,823,988 - 91,879,616 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034793913 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793914 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953923 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953924 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953925 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038208.1
Reference Protein Sequences
RefSeq Acc Id: XP_034793914   ⟸   XM_034938023
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CB68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793913   ⟸   XM_034938022
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CB68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953924   ⟸   XM_055097949
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054953925   ⟸   XM_055097950
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054953923   ⟸   XM_055097948
- Peptide Label: isoform X1
Protein Domains
Serine/threonine-protein phosphatase 4 regulatory


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041816 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061111.1 UniProtKB/TrEMBL
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
  Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  P4R3-like_central_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
NCBI Gene PPP4R3A ENTREZGENE
PANTHER ATP SYNTHASE GAMMA-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A UniProtKB/TrEMBL
Pfam PP4R3 UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A2R9CB68 ENTREZGENE, UniProtKB/TrEMBL