LYPLAL1 (lysophospholipase like 1) - Rat Genome Database

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Gene: LYPLAL1 (lysophospholipase like 1) Pan paniscus
Analyze
Symbol: LYPLAL1
Name: lysophospholipase like 1
RGD ID: 11827205
Description: ENCODES a protein that exhibits lipase activity (ortholog); INVOLVED IN negative regulation of Golgi to plasma membrane protein transport (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); Loeys-Dietz syndrome 4 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC117977157; lysophospholipase-like protein 1; uncharacterized LOC117977157
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2129,928,773 - 30,231,267 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1130,025,414 - 30,193,861 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01194,737,158 - 194,775,853 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11199,586,920 - 199,625,423 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1199,586,920 - 199,625,423 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LYPLAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2129,928,773 - 30,231,267 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1130,025,414 - 30,193,861 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01194,737,158 - 194,775,853 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11199,586,920 - 199,625,423 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1199,586,920 - 199,625,423 (+)Ensemblpanpan1.1panPan2
LYPLAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381219,173,878 - 219,445,496 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1219,173,869 - 219,212,865 (+)EnsemblGRCh38hg38GRCh38
GRCh371219,347,220 - 219,386,200 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361217,413,844 - 217,451,783 (+)NCBINCBI36Build 36hg18NCBI36
Build 341215,735,617 - 215,773,553NCBI
Celera1192,564,906 - 192,603,940 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1190,016,930 - 190,055,957 (+)NCBIHuRef
CHM1_11220,620,005 - 220,659,032 (+)NCBICHM1_1
T2T-CHM13v2.01218,409,848 - 218,681,408 (+)NCBIT2T-CHM13v2.0
Lyplal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,819,929 - 185,849,507 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,819,928 - 185,849,507 (-)EnsemblGRCm39 Ensembl
GRCm381186,087,732 - 186,117,310 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,087,731 - 186,117,310 (-)EnsemblGRCm38mm10GRCm38
MGSCv371187,911,611 - 187,941,189 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,788,668 - 187,818,098 (-)NCBIMGSCv36mm8
Celera1193,030,160 - 193,053,254 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.81NCBI
Lyplal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813100,158,060 - 100,189,339 (-)NCBIGRCr8
mRatBN7.21397,626,568 - 97,657,901 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1397,626,451 - 97,657,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13100,135,908 - 100,167,350 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013101,531,636 - 101,562,909 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01398,718,214 - 98,749,656 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013104,049,263 - 104,080,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13104,049,386 - 104,080,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013108,706,787 - 108,738,098 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413102,143,174 - 102,171,752 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113102,332,339 - 102,360,879 (-)NCBI
Celera1397,136,739 - 97,168,192 (-)NCBICelera
Cytogenetic Map13q26NCBI
Lyplal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555204,251,957 - 4,281,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555204,251,863 - 4,281,775 (-)NCBIChiLan1.0ChiLan1.0
LYPLAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,100,818 - 14,137,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,100,698 - 14,268,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,143,532 - 14,180,609 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,136,744 - 14,173,896 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,136,661 - 14,173,286 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13814,146,280 - 14,183,361 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03814,489,895 - 14,526,974 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03814,802,107 - 14,838,748 (+)NCBIUU_Cfam_GSD_1.0
Lyplal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934457,685,177 - 57,712,354 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366502,933,306 - 2,960,846 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366502,933,661 - 2,960,558 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYPLAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl108,946,487 - 9,062,412 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1108,946,463 - 9,061,033 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,029,585 - 11,088,269 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LYPLAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12510,370,715 - 10,408,807 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2510,370,814 - 10,408,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605510,766,878 - 10,806,116 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lyplal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248353,022,311 - 3,052,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248353,023,151 - 3,052,826 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000054307   ⟹   ENSPPAP00000031443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1199,586,920 - 199,625,423 (+)Ensembl
RefSeq Acc Id: XM_003814130   ⟹   XP_003814178
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,192,574 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,156,197 - 30,193,861 (-)NCBI
Mhudiblu_PPA_v01194,737,158 - 194,775,848 (+)NCBI
PanPan1.11199,586,920 - 199,625,423 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003814131   ⟹   XP_003814179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,192,574 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,156,197 - 30,193,861 (-)NCBI
Mhudiblu_PPA_v01194,737,158 - 194,775,853 (+)NCBI
PanPan1.11199,586,920 - 199,625,423 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034947070   ⟹   XP_034802961
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,192,574 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,156,197 - 30,193,861 (-)NCBI
Mhudiblu_PPA_v01194,737,158 - 194,775,853 (+)NCBI
RefSeq Acc Id: XM_034947085   ⟹   XP_034802976
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,192,574 - 30,230,201 (-)NCBI
NHGRI_mPanPan1130,156,197 - 30,192,767 (-)NCBI
Mhudiblu_PPA_v01194,738,241 - 194,775,848 (+)NCBI
RefSeq Acc Id: XM_063597124   ⟹   XP_063453194
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,192,574 - 30,231,267 (-)NCBI
RefSeq Acc Id: XR_008624365
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,062,812 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,025,414 - 30,193,861 (-)NCBI
RefSeq Acc Id: XR_008624368
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,095,468 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,068,475 - 30,193,861 (-)NCBI
RefSeq Acc Id: XR_008624371
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2129,928,773 - 30,231,267 (-)NCBI
NHGRI_mPanPan1130,072,675 - 30,193,861 (-)NCBI
RefSeq Acc Id: XR_010110061
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,062,812 - 30,231,267 (-)NCBI
RefSeq Acc Id: XR_010110062
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,095,468 - 30,231,267 (-)NCBI
RefSeq Acc Id: XR_010110063
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,104,134 - 30,231,267 (-)NCBI
RefSeq Acc Id: XR_010110064
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2130,104,134 - 30,231,267 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003814178 (Get FASTA)   NCBI Sequence Viewer  
  XP_003814179 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802961 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802976 (Get FASTA)   NCBI Sequence Viewer  
  XP_063453194 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031443.1
RefSeq Acc Id: XP_003814178   ⟸   XM_003814130
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003814179   ⟸   XM_003814131
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_034802961   ⟸   XM_034947070
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034802976   ⟸   XM_034947085
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BSN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000031443   ⟸   ENSPPAT00000054307
RefSeq Acc Id: XP_063453194   ⟸   XM_063597124
- Peptide Label: isoform X3

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038656 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054307.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  PLipase/COase/thioEstase UniProtKB/TrEMBL
KEGG Report pps:100984308 UniProtKB/TrEMBL
NCBI Gene LYPLAL1 ENTREZGENE
PANTHER LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 UniProtKB/TrEMBL
  LYSOPHOSPHOLIPASE-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9BSN0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 LYPLAL1  lysophospholipase like 1  LOC117977157  uncharacterized LOC117977157  Data merged from RGD:32732871 737654 PROVISIONAL