KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2) - Rat Genome Database

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Gene: KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2) Pan paniscus
Analyze
Symbol: KCNAB2
Name: potassium voltage-gated channel subfamily A regulatory beta subunit 2
RGD ID: 11826240
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); myoblast differentiation (ortholog); NADPH oxidation (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN axon initial segment (ortholog); axon terminus (ortholog); cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel, shaker-related subfamily, beta member 2; voltage-gated potassium channel subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21222,123,611 - 222,235,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,764,655 - 220,877,249 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v014,755,412 - 4,866,424 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,012,647 - 6,120,438 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,013,072 - 6,120,438 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21222,123,611 - 222,235,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,764,655 - 220,877,249 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v014,755,412 - 4,866,424 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,012,647 - 6,120,438 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,013,072 - 6,120,438 (+)Ensemblpanpan1.1panPan2
KCNAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3815,992,676 - 6,101,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl15,990,927 - 6,101,193 (+)EnsemblGRCh38hg38GRCh38
GRCh3716,052,736 - 6,161,240 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,008,967 - 6,083,110 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416,020,645 - 6,094,789NCBI
Celera15,201,212 - 5,275,339 (+)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,201,765 - 5,310,071 (+)NCBIHuRef
CHM1_116,041,041 - 6,149,632 (+)NCBICHM1_1
T2T-CHM13v2.015,518,502 - 5,626,866 (+)NCBIT2T-CHM13v2.0
Kcnab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,475,201 - 152,561,991 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,475,199 - 152,562,367 (-)EnsemblGRCm39 Ensembl
GRCm384152,390,744 - 152,477,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,390,742 - 152,477,910 (-)EnsemblGRCm38mm10GRCm38
MGSCv374151,764,853 - 151,851,588 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364151,234,544 - 151,321,279 (-)NCBIMGSCv36mm8
Celera4154,677,910 - 154,763,618 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.08NCBI
Kcnab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85168,182,228 - 168,270,760 (-)NCBIGRCr8
mRatBN7.25162,899,511 - 162,988,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,901,896 - 162,988,243 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,605,037 - 165,691,160 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,426,639 - 167,512,761 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,388,842 - 167,474,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,570,327 - 169,658,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,572,517 - 169,658,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05173,123,990 - 173,212,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,624,099 - 169,710,725 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,634,286 - 169,720,913 (-)NCBI
Celera5161,132,556 - 161,217,754 (-)NCBICelera
RH 3.4 Map51140.7RGD
Cytogenetic Map5q36NCBI
Kcnab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,369,288 - 6,442,885 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,371,212 - 6,442,888 (-)NCBIChiLan1.0ChiLan1.0
KCNAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1559,936,432 - 60,021,945 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl559,936,528 - 60,021,957 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha559,947,614 - 60,032,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,152,884 - 60,238,334 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,152,939 - 60,237,934 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,152,983 - 60,238,041 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,019,378 - 60,104,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,420,808 - 60,506,161 (+)NCBIUU_Cfam_GSD_1.0
Kcnab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,463,300 - 30,502,711 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936623940,678 - 985,388 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936623972,288 - 987,949 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl666,928,381 - 67,016,845 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1666,928,374 - 67,016,846 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2661,880,875 - 61,923,103 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNAB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,636,352 - 125,743,821 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,638,962 - 125,708,768 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605429,784,200 - 29,893,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnab2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,253,773 - 5,327,000 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248185,251,304 - 5,326,796 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000030664   ⟹   ENSPPAP00000008032
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16,013,072 - 6,120,433 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030668   ⟹   ENSPPAP00000008036
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16,044,621 - 6,120,438 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030671   ⟹   ENSPPAP00000008038
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16,070,424 - 6,117,799 (+)Ensembl
RefSeq Acc Id: XM_008975724   ⟹   XP_008973972
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,126,269 - 222,235,524 (-)NCBI
NHGRI_mPanPan11220,768,325 - 220,877,249 (-)NCBI
Mhudiblu_PPA_v014,755,412 - 4,863,365 (+)NCBI
PanPan1.116,012,647 - 6,117,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008975727   ⟹   XP_008973975
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,123,611 - 222,235,524 (-)NCBI
NHGRI_mPanPan11220,764,655 - 220,877,249 (-)NCBI
Mhudiblu_PPA_v014,755,412 - 4,866,424 (+)NCBI
PanPan1.116,012,647 - 6,120,438 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008975728   ⟹   XP_008973976
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,123,611 - 222,235,524 (-)NCBI
NHGRI_mPanPan11220,764,655 - 220,877,249 (-)NCBI
Mhudiblu_PPA_v014,755,412 - 4,866,424 (+)NCBI
PanPan1.116,012,647 - 6,120,438 (+)NCBI
Sequence:
RefSeq Acc Id: XM_057299890   ⟹   XP_057155873
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,123,611 - 222,199,667 (-)NCBI
NHGRI_mPanPan11220,764,655 - 220,840,622 (-)NCBI
RefSeq Acc Id: XM_063602135   ⟹   XP_063458205
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,126,269 - 222,235,524 (-)NCBI
RefSeq Acc Id: XM_063602138   ⟹   XP_063458208
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,126,269 - 222,190,918 (-)NCBI
RefSeq Acc Id: XM_063602141   ⟹   XP_063458211
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,126,269 - 222,199,591 (-)NCBI
RefSeq Acc Id: XM_063602148   ⟹   XP_063458218
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21222,126,269 - 222,191,132 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008973975   ⟸   XM_008975727
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008973976   ⟸   XM_008975728
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZYL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008973972   ⟸   XM_008975724
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000008038   ⟸   ENSPPAT00000030671
RefSeq Acc Id: ENSPPAP00000008032   ⟸   ENSPPAT00000030664
RefSeq Acc Id: ENSPPAP00000008036   ⟸   ENSPPAT00000030668
RefSeq Acc Id: XP_057155873   ⟸   XM_057299890
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZYL1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063458205   ⟸   XM_063602135
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458211   ⟸   XM_063602141
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458218   ⟸   XM_063602148
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458208   ⟸   XM_063602138
- Peptide Label: isoform X1
Protein Domains
NADP-dependent oxidoreductase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027250 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030664.1 UniProtKB/TrEMBL
  ENSPPAT00000030668.1 UniProtKB/TrEMBL
  ENSPPAT00000030671.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
InterPro K_chnl_volt-dep_bsu_KCNAB UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNAB-rel UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNAB1 UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNAB2 UniProtKB/TrEMBL
  NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
NCBI Gene KCNAB2 ENTREZGENE
PANTHER PTHR43150 UniProtKB/TrEMBL
  VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
PRINTS KCNAB1CHANEL UniProtKB/TrEMBL
  KCNAB2CHANEL UniProtKB/TrEMBL
  KCNABCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF51430 UniProtKB/TrEMBL
UniProt A0A2R8ZSU0_PANPA UniProtKB/TrEMBL
  A0A2R8ZW13_PANPA UniProtKB/TrEMBL
  A0A2R8ZYL1 ENTREZGENE, UniProtKB/TrEMBL