SMYD1 (SET and MYND domain containing 1) - Rat Genome Database

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Gene: SMYD1 (SET and MYND domain containing 1) Pan paniscus
Analyze
Symbol: SMYD1
Name: SET and MYND domain containing 1
RGD ID: 11825293
Description: ENCODES a protein that exhibits histone H3K4 methyltransferase activity (inferred); metal ion binding (inferred); transcription corepressor activity (inferred); INVOLVED IN chromatin remodeling (ortholog); heart development (ortholog); negative regulation of DNA-templated transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SMYD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,189,326 - 39,234,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,192,086 - 39,237,284 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,201,207 - 87,246,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,109,444 - 89,155,797 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,108,642 - 89,155,797 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SMYD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,189,326 - 39,234,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,192,086 - 39,237,284 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,201,207 - 87,246,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,109,444 - 89,155,797 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,108,642 - 89,155,797 (+)Ensemblpanpan1.1panPan2
SMYD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38288,067,825 - 88,113,384 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl288,067,825 - 88,113,384 (+)EnsemblGRCh38hg38GRCh38
GRCh37288,367,344 - 88,412,903 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36288,148,497 - 88,194,018 (+)NCBINCBI36Build 36hg18NCBI36
Celera288,373,097 - 88,418,568 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef287,289,577 - 87,335,154 (+)NCBIHuRef
CHM1_1288,296,599 - 88,342,189 (+)NCBICHM1_1
T2T-CHM13v2.0288,079,089 - 88,124,637 (+)NCBIT2T-CHM13v2.0
Smyd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,190,924 - 71,239,265 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,190,924 - 71,299,217 (-)EnsemblGRCm39 Ensembl
GRCm38671,213,940 - 71,262,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,213,940 - 71,322,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv37671,163,934 - 71,212,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,144,757 - 71,191,832 (-)NCBIMGSCv36mm8
Celera673,293,207 - 73,341,506 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.14NCBI
Smyd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84104,757,281 - 104,811,307 (-)NCBIGRCr8
mRatBN7.24103,195,330 - 103,252,989 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,200,322 - 103,311,766 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4108,590,805 - 108,642,610 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,365,906 - 104,417,714 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04102,972,276 - 103,022,881 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,071,122 - 99,125,143 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,074,535 - 99,125,111 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,848,270 - 163,904,185 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,423,556 - 104,475,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14104,664,623 - 104,728,216 (-)NCBI
Celera492,378,302 - 92,428,867 (-)NCBICelera
Cytogenetic Map4q32NCBI
Smyd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955424769,287 - 800,885 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955424769,287 - 800,646 (-)NCBIChiLan1.0ChiLan1.0
SMYD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,260,897 - 38,298,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1738,259,624 - 38,298,183 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1737,945,978 - 37,983,287 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01738,993,154 - 39,030,296 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1738,991,672 - 39,030,254 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,160,034 - 38,197,325 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,196,046 - 38,233,224 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,544,368 - 38,581,633 (-)NCBIUU_Cfam_GSD_1.0
Smyd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629280,077,527 - 80,110,874 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936712747,841 - 780,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936712747,060 - 781,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMYD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl357,867,250 - 57,918,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1357,866,078 - 57,918,576 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,559,524 - 60,607,410 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMYD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11418,676,396 - 18,721,532 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1418,676,394 - 18,720,903 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660801,054,806 - 1,098,662 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smyd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474916,399,346 - 16,432,887 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474916,400,037 - 16,432,956 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000045043   ⟹   ENSPPAP00000022236
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,108,642 - 89,155,797 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045059   ⟹   ENSPPAP00000022251
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,109,529 - 89,154,533 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045061   ⟹   ENSPPAP00000022253
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,109,529 - 89,152,926 (+)Ensembl
RefSeq Acc Id: XM_003805855   ⟹   XP_003805903
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,189,326 - 39,234,524 (-)NCBI
NHGRI_mPanPan12A39,192,086 - 39,237,284 (-)NCBI
Mhudiblu_PPA_v02A87,201,207 - 87,246,416 (+)NCBI
PanPan1.12A89,109,444 - 89,155,797 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003805903 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022236
  ENSPPAP00000022236.1
  ENSPPAP00000022251.1
  ENSPPAP00000022253.1
RefSeq Acc Id: XP_003805903   ⟸   XM_003805855
- UniProtKB: A0A2R9B432 (UniProtKB/TrEMBL),   A0A2R9AYV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000022251   ⟸   ENSPPAT00000045059
RefSeq Acc Id: ENSPPAP00000022253   ⟸   ENSPPAT00000045061
RefSeq Acc Id: ENSPPAP00000022236   ⟸   ENSPPAT00000045043
Protein Domains
MYND-type   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034302 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045043.1 UniProtKB/TrEMBL
  ENSPPAT00000045059.1 UniProtKB/TrEMBL
  ENSPPAT00000045061.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.160 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
  1.25.40.970 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
InterPro SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  SMYD1_SET UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
KEGG Report pps:100983230 UniProtKB/TrEMBL
NCBI Gene SMYD1 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SMYD UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 UniProtKB/TrEMBL
Pfam SET UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PROSITE SET UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
SMART SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt A0A2R9AYV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B432 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B447_PANPA UniProtKB/TrEMBL