PEX1 (peroxisomal biogenesis factor 1) - Rat Genome Database

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Gene: PEX1 (peroxisomal biogenesis factor 1) Pan paniscus
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Symbol: PEX1
Name: peroxisomal biogenesis factor 1
RGD ID: 11823451
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); hydrolase activity (inferred); INVOLVED IN microtubule-based peroxisome localization (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); epilepsy (ortholog); fundus dystrophy (ortholog); FOUND IN peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal ATPase PEX1; peroxisome biogenesis factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26110,372,447 - 110,413,736 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17158,635,150 - 158,678,317 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0784,484,965 - 84,526,309 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1798,081,018 - 98,122,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl798,081,021 - 98,122,335 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PEX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26110,372,447 - 110,413,736 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17158,635,150 - 158,678,317 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0784,484,965 - 84,526,309 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1798,081,018 - 98,122,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl798,081,021 - 98,122,335 (-)Ensemblpanpan1.1panPan2
PEX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38792,487,025 - 92,528,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl792,487,020 - 92,528,520 (-)EnsemblGRCh38hg38GRCh38
GRCh37792,116,339 - 92,157,834 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36791,954,273 - 91,995,781 (-)NCBINCBI36Build 36hg18NCBI36
Build 34791,760,990 - 91,802,460NCBI
Celera786,820,874 - 86,862,377 (-)NCBICelera
Cytogenetic Map7q21.2NCBI
HuRef786,725,109 - 86,766,599 (-)NCBIHuRef
CHM1_1792,046,373 - 92,087,866 (-)NCBICHM1_1
T2T-CHM13v2.0793,728,340 - 93,769,797 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2791,445,547 - 91,487,069 (-)NCBI
Pex1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3953,646,066 - 3,687,230 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl53,646,066 - 3,687,232 (+)EnsemblGRCm39 Ensembl
GRCm3853,596,066 - 3,637,230 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl53,596,066 - 3,637,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv3753,596,066 - 3,637,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3653,602,072 - 3,643,107 (+)NCBIMGSCv36mm8
Celera53,532,126 - 3,572,649 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.26NCBI
Pex1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8431,474,670 - 31,513,621 (-)NCBIGRCr8
mRatBN7.2430,519,950 - 30,558,953 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl430,519,955 - 30,558,921 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx435,492,702 - 35,531,639 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0431,418,781 - 31,457,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0429,814,810 - 29,853,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0427,659,376 - 27,698,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl427,659,381 - 27,698,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0427,562,602 - 27,601,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,235,147 - 27,275,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera425,944,627 - 25,983,247 (-)NCBICelera
Cytogenetic Map4q13NCBI
Pex1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554329,418,678 - 9,461,419 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554329,418,480 - 9,461,507 (-)NCBIChiLan1.0ChiLan1.0
PEX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11418,073,759 - 18,144,489 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1418,073,758 - 18,143,152 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1417,634,623 - 17,705,370 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01417,880,526 - 17,951,301 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1417,880,343 - 17,922,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11418,041,002 - 18,111,759 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01417,753,220 - 17,823,831 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01418,027,289 - 18,098,075 (-)NCBIUU_Cfam_GSD_1.0
Pex1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511831,459,732 - 31,507,925 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368031,291,702 - 1,340,178 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368031,291,867 - 1,340,123 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl972,385,475 - 72,444,582 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1972,385,755 - 72,444,718 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2979,114,205 - 79,173,283 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PEX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12156,493,424 - 56,535,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2156,493,435 - 56,535,154 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604247,744,820 - 47,787,087 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624809668,345 - 712,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624809668,248 - 713,036 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000060667   ⟹   ENSPPAP00000037765
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl798,081,021 - 98,122,335 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000060678   ⟹   ENSPPAP00000037776
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl798,081,455 - 98,122,245 (-)Ensembl
RefSeq Acc Id: XM_003809737   ⟹   XP_003809785
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,372,447 - 110,413,736 (-)NCBI
NHGRI_mPanPan17158,635,150 - 158,678,313 (-)NCBI
Mhudiblu_PPA_v0784,484,965 - 84,526,302 (-)NCBI
PanPan1.1798,081,021 - 98,122,335 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008962005   ⟹   XP_008960253
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,372,447 - 110,413,671 (-)NCBI
NHGRI_mPanPan17158,635,150 - 158,678,313 (-)NCBI
Mhudiblu_PPA_v0784,484,965 - 84,526,300 (-)NCBI
PanPan1.1798,081,023 - 98,122,245 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034964444   ⟹   XP_034820335
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,372,447 - 110,413,671 (-)NCBI
NHGRI_mPanPan17158,635,150 - 158,678,313 (-)NCBI
Mhudiblu_PPA_v0784,484,965 - 84,526,302 (-)NCBI
RefSeq Acc Id: XM_034964445   ⟹   XP_034820336
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,372,447 - 110,404,325 (-)NCBI
NHGRI_mPanPan17158,635,150 - 158,668,969 (-)NCBI
Mhudiblu_PPA_v0784,484,965 - 84,526,273 (-)NCBI
RefSeq Acc Id: XM_034964446   ⟹   XP_034820337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,378,413 - 110,413,736 (-)NCBI
NHGRI_mPanPan17158,643,055 - 158,678,313 (-)NCBI
Mhudiblu_PPA_v0784,490,905 - 84,526,309 (-)NCBI
RefSeq Acc Id: XM_055114705   ⟹   XP_054970680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,374,717 - 110,413,736 (-)NCBI
NHGRI_mPanPan17158,639,359 - 158,678,313 (-)NCBI
RefSeq Acc Id: XM_055114706   ⟹   XP_054970681
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26110,372,447 - 110,413,675 (-)NCBI
NHGRI_mPanPan17158,635,150 - 158,678,317 (-)NCBI
RefSeq Acc Id: XP_003809785   ⟸   XM_003809737
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C762 (UniProtKB/TrEMBL),   A0A2R9C789 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008960253   ⟸   XM_008962005
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_034820335   ⟸   XM_034964444
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820336   ⟸   XM_034964445
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820337   ⟸   XM_034964446
- Peptide Label: isoform X5
Ensembl Acc Id: ENSPPAP00000037776   ⟸   ENSPPAT00000060678
Ensembl Acc Id: ENSPPAP00000037765   ⟸   ENSPPAT00000060667
RefSeq Acc Id: XP_054970681   ⟸   XM_055114706
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054970680   ⟸   XM_055114705
- Peptide Label: isoform X3
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041612 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060667.1 UniProtKB/TrEMBL
  ENSPPAT00000060678.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  2.40.40.20 UniProtKB/TrEMBL
  3.10.330.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_ATPase_domain UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  Asp_de-COase-like_dom_sf UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  CDC48_domain_2-like_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PEX-N_a/b UniProtKB/TrEMBL
  PEX-N_psi_beta-barrel UniProtKB/TrEMBL
KEGG Report pps:100982929 UniProtKB/TrEMBL
NCBI Gene PEX1 ENTREZGENE
PANTHER AAA-FAMILY ATPASE UniProtKB/TrEMBL
  PTHR23077:SF12 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  PEX-1N UniProtKB/TrEMBL
  PEX-2N UniProtKB/TrEMBL
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF50692 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF54585 UniProtKB/TrEMBL
UniProt A0A2R9C762 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C789 ENTREZGENE, UniProtKB/TrEMBL