UPP2 (uridine phosphorylase 2) - Rat Genome Database
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Gene: UPP2 (uridine phosphorylase 2) Pan paniscus
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Symbol: UPP2
Name: uridine phosphorylase 2
RGD ID: 11822892
Description: ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); identical protein binding (ortholog); uridine phosphorylase activity (ortholog); INVOLVED IN CMP catabolic process (ortholog); dCMP catabolic process (ortholog); UMP catabolic process (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; mitochondrial neurogastrointestinal encephalopathy syndrome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cytosol (ortholog); type III intermediate filament (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B162,603,164 - 162,636,231 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,496,507 - 162,636,231 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B45,363,103 - 45,400,281 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
UPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B162,603,164 - 162,636,231 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,496,507 - 162,636,231 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B45,363,103 - 45,400,281 (+)NCBIMhudiblu_PPA_v0panPan3
UPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2157,876,702 - 158,136,154 (+)EnsemblGRCh38hg38GRCh38
GRCh382157,995,179 - 158,136,154 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372158,733,213 - 158,992,666 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372158,851,691 - 158,992,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362158,559,937 - 158,700,724 (+)NCBINCBI36hg18NCBI36
Build 342158,677,198 - 158,817,985NCBI
Celera2152,468,457 - 152,609,424 (+)NCBI
Cytogenetic Map2q24.1NCBI
HuRef2150,739,887 - 150,880,962 (+)NCBIHuRef
CHM1_12158,857,583 - 158,998,565 (+)NCBICHM1_1
Upp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39258,456,329 - 58,685,858 (+)NCBIGRCm39mm39
GRCm38258,566,317 - 58,795,846 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl258,567,298 - 58,792,971 (+)EnsemblGRCm38mm10GRCm38
MGSCv37258,607,596 - 58,643,079 (+)NCBIGRCm37mm9NCBIm37
MGSCv36258,570,571 - 58,606,054 (+)NCBImm8
Celera260,510,835 - 60,545,982 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
Upp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2343,273,048 - 43,317,417 (+)NCBI
Rnor_6.0 Ensembl344,806,106 - 44,846,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0344,806,106 - 44,846,464 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0349,922,719 - 49,961,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,492,002 - 40,536,956 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,380,721 - 40,432,184 (+)NCBI
Celera341,338,432 - 41,381,638 (+)NCBICelera
Cytogenetic Map3q21NCBI
Upp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544915,365,106 - 15,405,235 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544915,355,592 - 15,405,997 (-)NCBIChiLan1.0ChiLan1.0
Upp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493646920,465,767 - 20,513,084 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1565,088,284 - 65,131,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11565,088,652 - 65,131,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21572,235,731 - 72,280,652 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UPP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11043,510,752 - 43,545,133 (+)NCBI
Upp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247327,574,609 - 7,641,345 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003832702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000050162   ⟹   ENSPPAP00000027322
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B162,496,507 - 162,636,073 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050164   ⟹   ENSPPAP00000027324
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B162,603,164 - 162,636,231 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050166   ⟹   ENSPPAP00000027326
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B162,603,357 - 162,629,178 (+)Ensembl
RefSeq Acc Id: XM_003832702   ⟹   XP_003832750
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12B162,603,164 - 162,636,231 (+)NCBI
Mhudiblu_PPA_v02B45,363,103 - 45,400,281 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003832750 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003832750   ⟸   XM_003832702
- Sequence:
RefSeq Acc Id: ENSPPAP00000027324   ⟸   ENSPPAT00000050164
RefSeq Acc Id: ENSPPAP00000027322   ⟸   ENSPPAT00000050162
RefSeq Acc Id: ENSPPAP00000027326   ⟸   ENSPPAT00000050166
Protein Domains
PNP_UDP_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036723 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000027322 UniProtKB/TrEMBL
  ENSPPAP00000027324 UniProtKB/TrEMBL
  ENSPPAP00000027326 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050162 UniProtKB/TrEMBL
  ENSPPAT00000050164 UniProtKB/TrEMBL
  ENSPPAT00000050166 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1580 UniProtKB/TrEMBL
InterPro Nucleoside_phosphorylase_CS UniProtKB/TrEMBL
  Nucleoside_phosphorylase_d UniProtKB/TrEMBL
  Nucleoside_phosphorylase_sf UniProtKB/TrEMBL
  Uridine_phosphorylase_euk UniProtKB/TrEMBL
NCBI Gene UPP2 ENTREZGENE
Pfam PNP_UDP_1 UniProtKB/TrEMBL
PROSITE PNP_UDP_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53167 UniProtKB/TrEMBL
TIGRFAMs euk_UDPppase UniProtKB/TrEMBL
UniProt A0A2R9BCJ4_PANPA UniProtKB/TrEMBL
  A0A2R9BDT3_PANPA UniProtKB/TrEMBL
  A0A2R9BGC5_PANPA UniProtKB/TrEMBL