PKP1 (plakophilin 1) - Rat Genome Database

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Gene: PKP1 (plakophilin 1) Pan paniscus
Analyze
Symbol: PKP1
Name: plakophilin 1
RGD ID: 11817078
Description: ENCODES a protein that exhibits cadherin binding (inferred); lamin binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); cell-cell junction assembly (inferred); ASSOCIATED WITH ectodermal dysplasia (ortholog); Ectodermal Dysplasia-Skin Fragility Syndrome (ortholog); familial adult myoclonic epilepsy 5 (ortholog); FOUND IN cornified envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2148,049,593 - 48,099,255 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1148,013,571 - 48,063,272 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01176,881,154 - 176,930,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,182,829 - 181,232,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,182,829 - 181,232,347 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PKP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2148,049,593 - 48,099,255 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1148,013,571 - 48,063,272 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01176,881,154 - 176,930,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,182,829 - 181,232,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,182,829 - 181,232,347 (+)Ensemblpanpan1.1panPan2
PKP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381201,283,506 - 201,332,989 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1201,283,452 - 201,332,993 (+)EnsemblGRCh38hg38GRCh38
GRCh371201,252,634 - 201,302,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,519,203 - 199,568,740 (+)NCBINCBI36Build 36hg18NCBI36
Celera1174,376,403 - 174,425,974 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1172,418,808 - 172,468,387 (+)NCBIHuRef
CHM1_11202,674,744 - 202,724,331 (+)NCBICHM1_1
T2T-CHM13v2.01200,541,289 - 200,590,813 (+)NCBIT2T-CHM13v2.0
Pkp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,799,132 - 135,846,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,799,133 - 135,846,945 (-)EnsemblGRCm39 Ensembl
GRCm381135,871,394 - 135,919,207 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,871,395 - 135,919,207 (-)EnsemblGRCm38mm10GRCm38
MGSCv371137,767,972 - 137,815,601 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361137,687,806 - 137,735,435 (-)NCBIMGSCv36mm8
Celera1138,506,279 - 138,553,622 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map159.35NCBI
Pkp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,861,340 - 49,909,162 (-)NCBIGRCr8
mRatBN7.21347,309,607 - 47,357,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,309,614 - 47,357,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1349,917,668 - 49,965,528 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,205,725 - 51,253,592 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01348,468,998 - 48,517,003 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,705,174 - 52,753,089 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,705,174 - 52,752,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01357,753,232 - 57,800,892 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,910,028 - 48,958,983 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11348,924,070 - 48,973,030 (-)NCBI
Celera1347,626,371 - 47,674,244 (-)NCBICelera
Cytogenetic Map13q13NCBI
Pkp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540637,419,856 - 37,465,655 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540637,420,019 - 37,465,588 (+)NCBIChiLan1.0ChiLan1.0
PKP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.171,921,143 - 1,966,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl71,921,143 - 1,967,703 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,602,267 - 1,648,044 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.071,559,536 - 1,605,354 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,559,536 - 1,605,354 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.171,547,384 - 1,593,191 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,655,145 - 1,700,910 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,679,800 - 1,725,628 (-)NCBIUU_Cfam_GSD_1.0
Pkp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,855,210 - 73,903,643 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365673,089,881 - 3,138,331 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365673,089,902 - 3,138,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1023,689,380 - 23,735,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11023,689,394 - 23,735,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,237,387 - 28,276,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12528,083,358 - 28,129,356 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2528,081,983 - 28,128,173 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605528,880,279 - 28,925,618 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248079,372,099 - 9,419,067 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248079,374,206 - 9,419,075 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003823039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000015218   ⟹   ENSPPAP00000003306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1181,182,829 - 181,232,347 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000015227   ⟹   ENSPPAP00000003308
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1181,182,829 - 181,232,347 (+)Ensembl
RefSeq Acc Id: XM_003823039   ⟹   XP_003823087
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2148,049,593 - 48,099,255 (-)NCBI
NHGRI_mPanPan1148,013,571 - 48,063,272 (-)NCBI
Mhudiblu_PPA_v01176,881,154 - 176,930,814 (+)NCBI
PanPan1.11181,182,829 - 181,232,347 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823087 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003306.1
  ENSPPAP00000003308.1
Reference Protein Sequences
RefSeq Acc Id: XP_003823087   ⟸   XM_003823039
- UniProtKB: A0A2R8ZE41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000003308   ⟸   ENSPPAT00000015227
RefSeq Acc Id: ENSPPAP00000003306   ⟸   ENSPPAT00000015218


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000013857 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015218.1 UniProtKB/TrEMBL
  ENSPPAT00000015227.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Plakophilin/d_Catenin UniProtKB/TrEMBL
KEGG Report pps:100981577 UniProtKB/TrEMBL
NCBI Gene PKP1 ENTREZGENE
PANTHER PTHR10372 UniProtKB/TrEMBL
  PTHR10372:SF3 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
PROSITE ARM_REPEAT UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R8ZE41 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZKP2_PANPA UniProtKB/TrEMBL