FBN2 (fibrillin 2) - Rat Genome Database

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Gene: FBN2 (fibrillin 2) Pan paniscus
Analyze
Symbol: FBN2
Name: fibrillin 2
RGD ID: 11814854
Description: ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN embryonic limb morphogenesis (ortholog); glucose homeostasis (ortholog); limb morphogenesis (ortholog); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); Colorectal Neoplasms (ortholog); congenital contractural arachnodactyly (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibrillin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15129,435,248 - 129,715,699 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5129,435,248 - 129,715,711 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05123,673,209 - 123,953,741 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
FBN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15129,435,248 - 129,715,699 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5129,435,248 - 129,715,711 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05123,673,209 - 123,953,741 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FBN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385128,257,909 - 128,538,245 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5128,257,909 - 128,659,185 (-)EnsemblGRCh38hg38GRCh38
GRCh375127,593,601 - 127,873,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365127,621,500 - 127,901,634 (-)NCBINCBI36Build 36hg18NCBI36
Build 345127,621,627 - 127,901,195NCBI
Celera5123,725,605 - 124,005,813 (-)NCBICelera
Cytogenetic Map5q23.3NCBI
HuRef5122,784,332 - 123,064,311 (-)NCBIHuRef
CHM1_15127,026,171 - 127,306,337 (-)NCBICHM1_1
T2T-CHM13v2.05128,776,747 - 129,057,063 (-)NCBIT2T-CHM13v2.0
Fbn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391858,141,689 - 58,343,200 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1858,141,695 - 58,343,559 (-)EnsemblGRCm39 Ensembl
GRCm381858,008,623 - 58,210,572 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1858,008,623 - 58,210,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv371858,168,277 - 58,369,580 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361858,135,627 - 58,335,174 (-)NCBIMGSCv36mm8
Celera1859,320,066 - 59,527,555 (-)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1832.15NCBI
Fbn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21851,499,737 - 51,703,976 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1851,499,737 - 51,703,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1853,530,293 - 53,735,692 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01854,244,849 - 54,450,243 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01852,050,395 - 52,254,717 (-)NCBIRnor_WKY
Rnor_6.01853,068,495 - 53,272,254 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1853,068,495 - 53,181,503 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01852,284,482 - 52,487,739 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41853,883,011 - 53,914,001 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11853,946,953 - 54,078,364NCBI
Celera1849,628,059 - 49,829,139 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Fbn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554151,309,077 - 1,537,052 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554151,307,553 - 1,535,435 (-)NCBIChiLan1.0ChiLan1.0
FBN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,311,238 - 17,551,536 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,311,226 - 17,551,536 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,107,059 - 16,346,938 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,048,902 - 18,289,161 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,048,887 - 18,289,161 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11116,778,944 - 17,018,819 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,618,045 - 16,858,590 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,228,746 - 17,469,482 (-)NCBIUU_Cfam_GSD_1.0
Fbn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213139,961,651 - 140,183,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365041,535,624 - 1,757,435 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365041,535,629 - 1,757,386 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2131,152,127 - 131,370,881 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12131,150,665 - 131,370,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22136,502,442 - 136,602,300 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12331,204,652 - 31,476,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2331,204,391 - 31,475,820 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603446,561,539 - 46,838,522 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477412,863,446 - 13,116,545 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477412,863,446 - 13,116,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003826666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000059151   ⟹   ENSPPAP00000036259
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,435,248 - 129,715,711 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059161   ⟹   ENSPPAP00000036269
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,436,798 - 129,714,939 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059166   ⟹   ENSPPAP00000036274
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,436,798 - 129,714,939 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059172   ⟹   ENSPPAP00000036280
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,455,102 - 129,714,939 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059180   ⟹   ENSPPAP00000036288
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,506,296 - 129,714,939 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059188   ⟹   ENSPPAP00000036296
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,506,296 - 129,521,015 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059191   ⟹   ENSPPAP00000036299
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,619,951 - 129,714,939 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059195   ⟹   ENSPPAP00000036303
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5129,641,420 - 129,714,939 (-)Ensembl
RefSeq Acc Id: XM_003826666   ⟹   XP_003826714
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.15129,435,248 - 129,715,699 (-)NCBI
Mhudiblu_PPA_v05123,673,209 - 123,953,741 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003826714 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003826714   ⟸   XM_003826666
- Sequence:
RefSeq Acc Id: ENSPPAP00000036280   ⟸   ENSPPAT00000059172
RefSeq Acc Id: ENSPPAP00000036296   ⟸   ENSPPAT00000059188
RefSeq Acc Id: ENSPPAP00000036288   ⟸   ENSPPAT00000059180
RefSeq Acc Id: ENSPPAP00000036299   ⟸   ENSPPAT00000059191
RefSeq Acc Id: ENSPPAP00000036303   ⟸   ENSPPAT00000059195
RefSeq Acc Id: ENSPPAP00000036259   ⟸   ENSPPAT00000059151
RefSeq Acc Id: ENSPPAP00000036274   ⟸   ENSPPAT00000059166
RefSeq Acc Id: ENSPPAP00000036269   ⟸   ENSPPAT00000059161
Protein Domains
EGF-like   TB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040696 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000036259.1 UniProtKB/TrEMBL
  ENSPPAP00000036269.1 UniProtKB/TrEMBL
  ENSPPAP00000036274.1 UniProtKB/TrEMBL
  ENSPPAP00000036280.1 UniProtKB/TrEMBL
  ENSPPAP00000036288.1 UniProtKB/TrEMBL
  ENSPPAP00000036296.1 UniProtKB/TrEMBL
  ENSPPAP00000036299.1 UniProtKB/TrEMBL
  ENSPPAP00000036303.1 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059151.1 UniProtKB/TrEMBL
  ENSPPAT00000059161.1 UniProtKB/TrEMBL
  ENSPPAT00000059166.1 UniProtKB/TrEMBL
  ENSPPAT00000059172.1 UniProtKB/TrEMBL
  ENSPPAT00000059180.1 UniProtKB/TrEMBL
  ENSPPAT00000059188.1 UniProtKB/TrEMBL
  ENSPPAT00000059191.1 UniProtKB/TrEMBL
  ENSPPAT00000059195.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.290.10 UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  EGF_dom UniProtKB/TrEMBL
  FBN UniProtKB/TrEMBL
  Fibrillin_U_N UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  TB_dom UniProtKB/TrEMBL
  TB_dom_sf UniProtKB/TrEMBL
NCBI Gene FBN2 ENTREZGENE
PANTHER PTHR24039:SF26 UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  Fibrillin_U_N UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  PF00683 UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  PS51364 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
  SSF57581 UniProtKB/TrEMBL
UniProt A0A2R9C2V9_PANPA UniProtKB/TrEMBL
  A0A2R9C2Y0_PANPA UniProtKB/TrEMBL
  A0A2R9C3A5_PANPA UniProtKB/TrEMBL
  A0A2R9C3B6_PANPA UniProtKB/TrEMBL
  A0A2R9C3C1_PANPA UniProtKB/TrEMBL
  A0A2R9C3G3_PANPA UniProtKB/TrEMBL
  A0A2R9C5W4_PANPA UniProtKB/TrEMBL
  A0A2R9C5X9_PANPA UniProtKB/TrEMBL