KCNU1 (potassium calcium-activated channel subfamily U member 1) - Rat Genome Database

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Gene: KCNU1 (potassium calcium-activated channel subfamily U member 1) Pan paniscus
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Symbol: KCNU1
Name: potassium calcium-activated channel subfamily U member 1
RGD ID: 11813247
Description: ENCODES a protein that exhibits large conductance calcium-activated potassium channel activity (inferred); monoatomic ion channel activity (inferred); potassium channel activity (inferred); INVOLVED IN establishment of localization in cell (ortholog); potassium ion transport (ortholog); protein stabilization (ortholog); ASSOCIATED WITH genetic disease (ortholog); Spermatogenic Failure 79 (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN membrane (inferred); postsynaptic membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel subfamily U member 1
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2755,334,556 - 55,490,675 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1831,058,504 - 31,209,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0836,081,180 - 36,231,982 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1833,261,491 - 33,412,532 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl833,261,041 - 33,412,972 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
KCNU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2755,334,556 - 55,490,675 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1831,058,504 - 31,209,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0836,081,180 - 36,231,982 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1833,261,491 - 33,412,532 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl833,261,041 - 33,412,972 (+)Ensemblpanpan1.1panPan2
KCNU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38836,784,374 - 36,936,125 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl836,784,324 - 36,936,125 (+)EnsemblGRCh38hg38GRCh38
GRCh37836,641,892 - 36,793,643 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36836,761,000 - 36,912,801 (+)NCBINCBI36Build 36hg18NCBI36
Build 34836,761,058 - 36,912,799NCBI
Celera835,592,114 - 35,743,914 (+)NCBICelera
Cytogenetic Map8p11.23NCBI
HuRef835,176,234 - 35,328,030 (+)NCBIHuRef
CHM1_1836,844,078 - 36,995,868 (+)NCBICHM1_1
T2T-CHM13v2.0837,060,432 - 37,212,188 (+)NCBIT2T-CHM13v2.0
Kcnu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,338,656 - 26,427,971 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl826,339,651 - 26,427,967 (+)EnsemblGRCm39 Ensembl
GRCm38825,848,627 - 25,937,943 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,849,623 - 25,937,939 (+)EnsemblGRCm38mm10GRCm38
MGSCv37826,960,095 - 27,048,406 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36827,315,201 - 27,403,347 (+)NCBIMGSCv36mm8
Celera827,317,965 - 27,405,769 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.17NCBI
Kcnu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81672,844,692 - 72,932,216 (-)NCBIGRCr8
mRatBN7.21666,141,696 - 66,229,493 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,141,976 - 66,229,465 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01670,913,825 - 70,998,593 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1670,913,817 - 70,998,575 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,577,547 - 70,663,252 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,517,667 - 70,604,946 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1664,052,606 - 64,139,348 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
KCNU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11628,333,783 - 28,478,433 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1628,334,505 - 28,478,385 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1628,849,104 - 28,996,123 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01630,237,142 - 30,381,628 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1630,237,799 - 30,381,574 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11628,453,068 - 28,597,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01629,030,890 - 29,175,529 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01629,069,713 - 29,214,130 (-)NCBIUU_Cfam_GSD_1.0
Kcnu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494350,995,030 - 51,159,837 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936710331,610 - 465,981 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936710301,387 - 465,935 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1549,316,673 - 49,444,385 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11549,317,110 - 49,444,337 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21556,423,626 - 56,550,938 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103215616
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1834,798,614 - 34,960,466 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl834,826,303 - 34,960,259 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666335277 - 87,857 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247806,748,764 - 6,904,697 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247806,751,411 - 6,929,900 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000052293   ⟹   ENSPPAP00000029444
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl833,261,041 - 33,412,972 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000052308   ⟹   ENSPPAP00000029459
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl833,261,501 - 33,399,676 (+)Ensembl
RefSeq Acc Id: XM_055116455   ⟹   XP_054972430
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2755,339,697 - 55,490,674 (+)NCBI
NHGRI_mPanPan1831,058,504 - 31,209,436 (+)NCBI
RefSeq Acc Id: XM_055116456   ⟹   XP_054972431
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2755,339,697 - 55,490,675 (+)NCBI
NHGRI_mPanPan1831,058,504 - 31,209,437 (+)NCBI
RefSeq Acc Id: XM_063606715   ⟹   XP_063462785
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2755,334,556 - 55,488,198 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054972430 (Get FASTA)   NCBI Sequence Viewer  
  XP_054972431 (Get FASTA)   NCBI Sequence Viewer  
  XP_063462785 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029444.1
  ENSPPAP00000029459.1
RefSeq Acc Id: ENSPPAP00000029459   ⟸   ENSPPAT00000052308
RefSeq Acc Id: ENSPPAP00000029444   ⟸   ENSPPAT00000052293
RefSeq Acc Id: XP_054972431   ⟸   XM_055116456
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BIH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054972430   ⟸   XM_055116455
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BIH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063462785   ⟸   XM_063606715
- Peptide Label: isoform X3

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037711 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052293.1 UniProtKB/TrEMBL
  ENSPPAT00000052308.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_BK_asu UniProtKB/TrEMBL
  K_chnl_Slo-like UniProtKB/TrEMBL
  Slowpoke-like_C UniProtKB/TrEMBL
NCBI Gene KCNU1 ENTREZGENE
PANTHER CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN UniProtKB/TrEMBL
  POTASSIUM CHANNEL SUBFAMILY U MEMBER 1 UniProtKB/TrEMBL
Pfam BK_channel_a UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  Slowpoke_C UniProtKB/TrEMBL
PRINTS BKCHANNELA UniProtKB/TrEMBL
  KCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A2R9BIG3_PANPA UniProtKB/TrEMBL
  A0A2R9BIH4 ENTREZGENE, UniProtKB/TrEMBL