NADSYN1 (NAD synthetase 1) - Rat Genome Database

Name: NADSYN1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NADSYN1 (NAD synthetase 1) Pan paniscus

Analyze

Symbol:

NADSYN1

Name:

NAD synthetase 1

RGD ID:

11812717

Description:

ENCODES a protein that exhibits ATP binding (inferred); glutaminase activity (inferred); ligase activity (inferred); INVOLVED IN 'de novo' NAD biosynthetic process (inferred); NAD biosynthetic process (inferred); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; de novo nicotinamide adenine dinucleotide biosynthetic pathway; glutamic acid/glutamate metabolic pathway; ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); cerebral folate receptor alpha deficiency (ortholog); Dyslipidemias (ortholog); FOUND IN cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

glutamine-dependent NAD(+) synthetase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NADSYN1 (NAD synthetase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Nadsyn1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nadsyn1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nadsyn1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NADSYN1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nadsyn1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NADSYN1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NADSYN1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nadsyn1 (NAD synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	72,339,234 - 72,432,547 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	73,376,859 - 73,450,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	66,464,320 - 66,537,649 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	69,735,871 - 69,793,226 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	69,735,871 - 69,788,953 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-methylglutaconic aciduria type 7b (ISO)

cerebral folate receptor alpha deficiency (ISO)

Dyslipidemias (ISO)

genetic disease (ISO)

high grade glioma (ISO)

intellectual disability (ISO)

Smith-Lemli-Opitz syndrome (ISO)

Vertebral, Cardiac, Renal, and Limb Defects Syndrome 1 (ISO)

Vertebral, Cardiac, Renal, and Limb Defects Syndrome 3 (ISO)

Vitamin D Deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

'de novo' NAD biosynthetic process (IEA)

NAD biosynthetic process (IEA)

Cellular Component

cytoplasm (IEA)

Molecular Function

ATP binding (IEA)

glutaminase activity (IEA)

ligase activity (IEA)

NAD+ synthase (glutamine-hydrolyzing) activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

2-hydroxyglutaric aciduria pathway (ISO)

de novo nicotinamide adenine dinucleotide biosynthetic pathway (ISO)

glutamic acid/glutamate metabolic pathway (ISO)

homocarnosinosis pathway (ISO)

niacin metabolic pathway (ISO)

nicotinamide adenine dinucleotide biosynthesis, the salvage pathway (ISO)

succinic semialdehyde dehydrogenase deficiency pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NADSYN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	72,339,234 - 72,432,547 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	73,376,859 - 73,450,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	66,464,320 - 66,537,649 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	69,735,871 - 69,793,226 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	69,735,871 - 69,788,953 (+)	Ensembl	panpan1.1		panPan2

NADSYN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	71,453,203 - 71,501,816 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	71,453,109 - 71,524,107 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	71,164,249 - 71,212,862 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	70,841,865 - 70,890,232 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	68,457,742 - 68,506,114 (+)	NCBI		Celera
Cytogenetic Map	11	q13.4	NCBI
HuRef	11	67,457,809 - 67,506,195 (+)	NCBI		HuRef
CHM1_1	11	71,048,194 - 71,096,600 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	71,380,158 - 71,428,792 (+)	NCBI		T2T-CHM13v2.0

Nadsyn1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	143,349,326 - 143,376,598 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	143,349,321 - 143,376,586 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	143,795,589 - 143,822,862 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	143,795,584 - 143,822,849 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	150,981,499 - 151,008,746 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	143,604,984 - 143,632,231 (-)	NCBI		MGSCv36	mm8
Celera	7	143,551,948 - 143,579,416 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	88.32	NCBI

Nadsyn1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	208,410,914 - 208,439,242 (-)	NCBI		GRCr8
mRatBN7.2	1	198,981,559 - 199,009,853 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	198,981,604 - 199,009,869 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	207,361,638 - 207,389,345 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	214,443,560 - 214,471,187 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	207,117,728 - 207,145,356 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	216,985,710 - 217,013,743 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	216,985,714 - 217,013,702 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	223,722,251 - 223,869,610 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	204,187,585 - 204,237,424 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	204,341,037 - 204,390,877 (-)	NCBI
Celera	1	196,545,283 - 196,572,552 (-)	NCBI		Celera
Cytogenetic Map	1	q42	NCBI

Nadsyn1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	15,066,708 - 15,114,049 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	15,067,711 - 15,113,942 (-)	NCBI	ChiLan1.0	ChiLan1.0

NADSYN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	47,216,547 - 47,254,582 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	47,216,577 - 47,254,514 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	45,824,631 - 45,862,252 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	47,897,151 - 47,934,979 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	47,897,155 - 47,934,998 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	47,338,020 - 47,375,995 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	46,924,178 - 46,961,816 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	47,670,678 - 47,708,646 (-)	NCBI		UU_Cfam_GSD_1.0

Nadsyn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	3,451,773 - 3,480,634 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936794	1,396,703 - 1,423,709 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936794	1,394,975 - 1,423,807 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NADSYN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	2,334,799 - 2,372,361 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	2,334,793 - 2,372,356 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	725,955 - 739,214 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NADSYN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	3,189,054 - 3,243,087 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	3,188,348 - 3,238,435 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	100,374,580 - 100,430,183 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nadsyn1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	16,069,780 - 16,115,162 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	16,069,895 - 16,115,029 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003828773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034933266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034933267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063608636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001338636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004665160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_008620113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010113467	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010113468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010113469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_608927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000001879 ⟹ ENSPPAP00000000437

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	69,735,871 - 69,788,953 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000001959 ⟹ ENSPPAP00000000446

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	69,740,595 - 69,788,764 (+)	Ensembl

RefSeq Acc Id:

XM_003828773 ⟹ XP_003828821

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,234 - 72,387,893 (+)	NCBI
NHGRI_mPanPan1	11	73,381,428 - 73,430,082 (+)	NCBI
Mhudiblu_PPA_v0	11	66,468,972 - 66,517,549 (+)	NCBI
PanPan1.1	11	69,740,407 - 69,788,953 (+)	NCBI

Sequence:

show sequence

AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTTCTCCTTGGCCGGAGCCTCAA
CGGATGGGCGGGGAGGGGGCGGGGCCGGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCT
CGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTGCGGCCAGGATGG
GCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTT
GCAAAGAATTTTAAAGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCA
GAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATTACGAGTCGGACACCCTCTTGCACT
CGTTTGAAGTCCTAGCGGCCCTTCTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGG
GATGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATC
CTGCTCATCAGACCCAAGATGGCCTTGGCCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCA
CCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATACAGGACCTGAC
AAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGT
GAGATCTGTGAGGAGCTCTGGACACCCCACAGCCCACACATCGACATGGGCCTGGATGGCGTGG
AGATCATCACCAACGCCTCGGGCAGCCACCACGTTCTGCGCAAAGCCAACACCAGGGTGGATCT
CGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGCGAC
GGGGACCGCCTGTACTACGACGGCTGCGCCATGATCGCCATGAACGGAAGCGTCTTTGCTCAAG
GATCCCAGTTTTCTCTGGATGACGTGGAAGTCCTGACGGCCACGCTGGATCTGGAGGACGTCCG
GAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCTACCCCAGA
GTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCG
AGTGGAAATACCACAGCCCTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTT
TTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTGGCGGGGTGGACAGCGCAGCC
ACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAATGAGG
AAGTGCTGGCTGATGTCCGCACCATTGTGAACCAGATCAGCTACACCCCCCAGGATCCCCGAGA
CCTCTGTGGACGCATACTGACCACCTGCTACATGGCCAGCAAGAACTCCTCCCAGGAGACGTGC
ACCCGGGCCAGAGAGTTGGCCCAGCAGATTGGAAGCCACCACATCAGTCTCAACATCGATCCAG
CCGTGAAGGCCGTCATGGGCATCTTCAGCCTGGTGACGGGGAAGAGCCCTCTGTTTGCAGCTCA
TGGAGGAAGCAGCAGGGAAAACCTGGCGCTGCAAAATGTGCAGGCTCGAATACGGATGGTCCTC
GCCTATCTGTTTGCTCAGTTGAGCCTCTGGTCTCGGGGCGTCCACGGTGGGCTCCTCGTGCTGG
GATCCGCCAACGTGGATGAGAGTCTCCTGGGCTACCTGACCAAGTACGACTGCTCCAGTGCGGA
CATCAACCCCATAGGCGGGATCAGCAAGACGGACCTCAGGGTCTTCGTCCAGTTCTGCATCCAG
CGCTTCCAGCTTCCTGCCCTGCAGAGCATCCTGTTGGCGCCGGCCACTGCAGAGCTGGAGCCCT
TGGCTGATGGACAGGTGTCCCAGACTGACGAGGAAGATATGGGGATGACATATGCGGAGCTCTC
AGTCTATGGGAAACTCAGGAAGGTGGCCAAGATGGGGCCCTACAGCATGTTCTGCAAACTCCTC
GGCATGTGGAGACACATCTGCACCCCGAGACAGGTCGCTGACAAAGTGAAGCGGTTTTTCTCCA
AGTACTCCATGAACAGACACAAGATGACCACGCTCACACCCGCGTACCACGCCGAGAACTACAG
CCCTGAGGACAACAGGTTTGATCTGCGACCATTTCTGTACAACACAAGCTGGCCTTGGCAGTTT
CGGTGCATAGAAAATCAGGTGCTACAGCTCGAGAGGGCAGAGCCACAGTCCCTGGACGGCGTGG
ACTGAGGCCGGTTCCTTCCTGGAGGCCTCCTGTCCTCGGGGACCCCAGCACCTCATCATCAGCA
TTGCTGGAGCCAAGGGTAGGAGCCCTACACTAGGAGCCCAGGATGGGACGGCGCATCAGCCGAG
AGGGAGGGAACTTTTCAGTCAAATTCCTCAAAAAGAGGCTGGAATAAAGCCTGGGCTTAAAAAG
AG

hide sequence

RefSeq Acc Id:

XM_034933266 ⟹ XP_034789157

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,242 - 72,387,640 (+)	NCBI
NHGRI_mPanPan1	11	73,381,436 - 73,429,836 (+)	NCBI
Mhudiblu_PPA_v0	11	66,468,969 - 66,515,888 (+)	NCBI

RefSeq Acc Id:

XM_063608636 ⟹ XP_063464706

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,296 - 72,385,083 (+)	NCBI

RefSeq Acc Id:

XR_001338636

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,296 - 72,392,641 (+)	NCBI
NHGRI_mPanPan1	11	73,381,490 - 73,434,821 (+)	NCBI
Mhudiblu_PPA_v0	11	66,468,972 - 66,521,973 (+)	NCBI
PanPan1.1	11	69,740,407 - 69,792,445 (+)	NCBI

Sequence:

show sequence

AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTTCTCCTTGGCCGGAGCCTCAA
CGGATGGGCGGGGAGGGGGCGGGGCCGGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCT
CGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTGCGGCCAGGATGG
GCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTT
GCAAAGAATTTTAAAGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCA
GAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATTACGAGTCGGACACCCTCTTGCACT
CGTTTGAAGTCCTAGCGGCCCTTCTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGG
GATGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATC
CTGCTCATCAGACCCAAGATGGCCTTGGCCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCA
CCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATACAGGACCTGAC
AAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGT
GAGATCTGTGAGGAGCTCTGGACACCCCACAGCCCACACATCGACATGGGCCTGGATGGCGTGG
AGATCATCACCAACGCCTCGGGCAGCCACCACGTTCTGCGCAAAGCCAACACCAGGGTGGATCT
CGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGCGAC
GGGGACCGCCTGTACTACGACGGCTGCGCCATGATCGCCATGAACGGAAGCGTCTTTGCTCAAG
GATCCCAGTTTTCTCTGGATGACGTGGAAGTCCTGACGGCCACGCTGGATCTGGAGGACGTCCG
GAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGGCCAGCAGGGCGAGCCCCTACCCCAGA
GTGAAGGTGGACTTTGCCCTCTCGTGCCACGAGGACTTGCTGGCACCCATCTCTGAGCCCATCG
AGTGGAAATACCACAGCCCTGAGGAGGAGATAAGCCTTGGACCTGCCTGCTGGCTCTGGGATTT
TTTAAGACGAAGTCAACAGGCAGGGTTTTTGCTGCCCTTGAGTGGCGGGGTGGACAGCGCAGCC
ACCGCCTGCCTCATCTACTCCATGTGCTGCCAGGTCTGCGAGGCCGTGAGGAGTGGAAATGAGG
AAGTGCTGGCTGATGTCCGCACCATTGTGAACCAGATCAGCTACACCCCCCAGGATCCCCGAGA
CCTCTGTGGACGCATACTGACCACCTGCTACATGGCCAGCAAGAACTCCTCCCAGGAGACGTGC
ACCCGGGCCAGAGAGTTGGCCCAGCAGATTGGAAGCCACCACATCAGTCTCAACATCGATCCAG
CCGTGAAGGCCGTCATGGGCATCTTCAGCCTGGTGACGGGGAAGAGCCCTCTGTTTGCAGCTCA
TGGAGGAAGCAGCAGGGAAAACCTGGCGCTGCAAAATGTGCAGGCTCGAATACGGATGGTCCTC
GCCTATCTGTTTGCTCAGTTGAGCCTCTGGTCTCGGGGCGTCCACGGTGGGCTCCTCGTGCTGG
GATCCGCCAACGTGGATGAGAGTCTCCTGGGCTACCTGACCAAGTACGACTGCTCCAGTGCGGA
CATCAACCCCATAGGCGGGATCAGCAAGACGGACCTCAGGGTCTTCGTCCAGTTCTGCATCCAG
CGCTTCCAGCTTCCTGCCCTGCAGAGCATCCTGTTGGCGCCGGCCACTGCAGAGCTGGAGCCCT
TGGCTGATGGACAGGTGTCCCAGACTGACGAGGAAGATATGGGGATGACATATGCGGAGCTCTC
AGTCTATGGGAAACTCAGGAAGGTGGCCAAGATGGGGCCCTACAGCATGTTCTGCAAACTCCTC
GGCATGTGGAGACACATCTGCACCCCGAGACAGGTCGCTGACAAAGTGAAGCGGTTTTTCTCCA
AGTACTCCATGAACAGACACAAGATGACCACGCTCACACCCGCGTACCACGCCGAGAACTACAG
CCCTGAGGACAACAGGTTTGATCTGCGACCATTTCTGTACAACACAAGCTGGCCTTGGCAGTTT
CGGTGCATAGAAAATCAGGTGCTACAGCTCGAGAGGGCAGAGCCACAGTCCCTGGACGGCGTGG
ACTGAGGCCGGTTCCTTCCTGGAGGCCTCCTGTCCTCGGGGACCCCAGCACCTCATCATCAGCA
TTGCTGGAGCCAAGGAGTCTGTTACCCACGTCACATCATGGATGCCCCCTGCCCGGATAGGTCT
GAGTGCACTGGGGTGGCCGGCACCCCACACCTTCTCAGGGAGCACCCAGCAGGATACCTGAGAT
TCTCCTTAGGCCTTGGATGGGAGCTGGAGGCTTCTGGCTGCCTTCTGCACCCCAGATGTGTGGC
AACGGGGTGGGGAGTGTGTCCCCCGAAAGATGATCAGGTGAGGCTGGGACCCTGAAGGCAGCCC
CATCCTGTGGAATTACCCTCGGAGGCTCCGAAACTTCCCACCTGCAGGAGCTGAGCTCAGGGGC
ACCAGACCCTGGTCCCCAACCTTCAAGTTATAGGGTGGTGTCCCCCAGTTACAGGGCAGTGTCC
CCAGTTACAGGATACTGTCCCTCAGTCATAGGTTAGTATCTTCTGGTTACAGGATAGCATCCCG
TCAGTTATAGGGCAGTGTCCCCCCAGTCATAGCATAGTGTATCCCCAAGTTACAGGGTAGTGTC
CCCAGTTATAAGGCAATGTTCCCCCATTATAGTGTCCCCAGTTATGAGGTAATGTCTCCCAGTT
ACAGGGTAATGTCCCCCAGTTATAGGGTGATGTCCCCACAGTTATAGGGTGATGTCCCCGCAGT
TACAGGTGAATGTCCCTCCAGTTATAGGGTGATGTCCCCCAGTTATAGGTGAATGTCTCCCCAG
TTATAGGGTAAGTCCCCACAGTTATAGGGTGACGTCCATCAGTTATAGGGCAATGTCCCCCCAG
TTACTGGGCTGTGTCCCCCAATTACAGGGCAATGTCCCCTCATAGTGTCTCCCAGTTATACAGT
ATTGTCCCCCCATTATAAGGTAGTATCGCCAGTTACTAGATAGTGTCCCCCAGTAACAGGATAA
TGTCCCCCAATTGCAGGGCAATGTCCCCCATTATAGTGTCCCCAAGTTATAAGCTGGAGTCCCC
CAGTAACAGGATAATAGGATAGTGTTCCCCAGTACAGGGCAGTGTCCCCAGTTACTCACTAGTG
TCCCCTAGTAACAGGGCAGTGTCCACCCAGATACAGCCTAGTGTCCCTCAGTTACACAATAGTG
TGTCCCCCAGTGGTAGGACAGTCTACTACTGAGTCCTCCTGGCATGAGTCGAGCTGAGATTAGG
ATAGGGTAGTGACCCTTCAGTTTTGGGGAAGGGACCAGAGCTCGGCCAGTGAGAAGCTTCCAGC
TCCGTCTGGCCATATCCAGGTTGCTGAGGGTCCCGGGCTCTGTCCTTAAACCTCATCACTGACA
TGACCCAGCAAACCTCCTCAAGAGGAAAAAGTCCCCTTGGGTCAAACACAGCTTGTGCAGGTCT
CGGGGACCTCCTCCTGCCATCCTGGGGACGCTGTGGAGAATGGAGATGCACAGGGGGCTTTGTC
CTCTCCTCTGCCTTTTGGAGAAAATATTTCACTCAAGGCAAACGCAGCCTGAGGGCAGCACAGG
GGACCCCAAGGCTCACTGCGCATTTCTAGTCGCCCCCAAACGCGTGGGTTTTCCTCCTGTTCTC
CTCGTGGGTGCCTTTGCTCATTCTCATCCTCCTGTTCTCATCCAGTCTGCCCAGTCTGACCGGC
TCCCAGCAGCATCCGCCCAAAAGTTTCTCCCATGACAGCAGGAAGCAGCCTCAGACAATACATG
ATGGACAGGCCTGGCTGTGTTCCAATAGAACCCCGAGTCAGTCAGCCCGAGCCTCCCTCTCAGC
TGGATACTGTTAATGACAGGGGTACACATTCCCCTCCCCTTTCCAATGTTTTAAAACTCTAGGA
CAGTGATTCTCAAACACTTTGGTCTCAAAACCCCTAAGAGCATTTGCTTATGTGGCTTTTATCT
GTTGATAGTTGCTACCTGAGAAATTAAAACTGAGAAATCTAAAAATAGATTTATTTTAGGAAGT
CACTAAAAATAATAAGCCCATTGCATGTTAACATGAAATAGCATATTTTTACAAAAAAATAAGT
TTTCTAAAA

hide sequence

RefSeq Acc Id:

XR_004665160

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,242 - 72,414,322 (+)	NCBI
NHGRI_mPanPan1	11	73,381,490 - 73,450,206 (+)	NCBI
Mhudiblu_PPA_v0	11	66,468,972 - 66,537,649 (+)	NCBI

RefSeq Acc Id:

XR_008620113

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,296 - 72,392,641 (+)	NCBI
NHGRI_mPanPan1	11	73,381,490 - 73,434,773 (+)	NCBI

RefSeq Acc Id:

XR_010113467

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,296 - 72,392,641 (+)	NCBI

RefSeq Acc Id:

XR_010113468

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,242 - 72,414,322 (+)	NCBI

RefSeq Acc Id:

XR_010113469

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	72,339,242 - 72,432,547 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003828821	(Get FASTA)	NCBI Sequence Viewer
	XP_034789157	(Get FASTA)	NCBI Sequence Viewer
	XP_063464706	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000000437.1
	ENSPPAP00000000446
	ENSPPAP00000000446.1

RefSeq Acc Id:	XP_003828821 ⟸ XM_003828773
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R8ZCV7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLL HSFEVLAALLESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRW FTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDG VEIITNASGSHHVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFA QGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEP IEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGN EEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNID PAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVHGGLLV LGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRVFVQFCIQRFQLPALQSILLAPATAELE PLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFF SKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAEPQSLDG VD hide sequence

RefSeq Acc Id:	XP_034789157 ⟸ XM_034933266
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZCV7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSPPAP00000000437 ⟸ ENSPPAT00000001879

RefSeq Acc Id:

ENSPPAP00000000446 ⟸ ENSPPAT00000001959

RefSeq Acc Id:	XP_063464706 ⟸ XM_063608636
- Peptide Label:	isoform X2

Protein Domains

CN hydrolase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000001380	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000001879.1	UniProtKB/TrEMBL
	ENSPPAT00000001959.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.620	UniProtKB/TrEMBL
	3.60.110.10	UniProtKB/TrEMBL
InterPro	C-N_Hydrolase	UniProtKB/TrEMBL
	C-N_Hydrolase_sf	UniProtKB/TrEMBL
	Gln-dep_NAD_synthase	UniProtKB/TrEMBL
	NAD/GMP_synthase	UniProtKB/TrEMBL
	NAD_synthase	UniProtKB/TrEMBL
	Rossmann-like_a/b/a_fold	UniProtKB/TrEMBL
NCBI Gene	NADSYN1	ENTREZGENE
PANTHER	GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE	UniProtKB/TrEMBL
	PTHR23090	UniProtKB/TrEMBL
Pfam	CN_hydrolase	UniProtKB/TrEMBL
	NAD_synthase	UniProtKB/TrEMBL
PIRSF	NADS_GAT	UniProtKB/TrEMBL
PROSITE	CN_HYDROLASE	UniProtKB/TrEMBL
Superfamily-SCOP	Adenine nucleotide alpha hydrolases-like	UniProtKB/TrEMBL
	SSF56317	UniProtKB/TrEMBL
UniProt	A0A2R8Z6M8_PANPA	UniProtKB/TrEMBL
	A0A2R8ZCV7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB