GREM2 (gremlin 2, DAN family BMP antagonist) - Rat Genome Database

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Gene: GREM2 (gremlin 2, DAN family BMP antagonist) Pan paniscus
Analyze
Symbol: GREM2
Name: gremlin 2, DAN family BMP antagonist
RGD ID: 11811158
Description: ENCODES a protein that exhibits BMP binding (ortholog); heparin binding (ortholog); identical protein binding (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); determination of dorsal identity (ortholog); embryonic body morphogenesis (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); Hereditary Leiomyomatosis and Renal Cell Cancer (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: gremlin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11221,023,212 - 221,148,149 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1221,026,605 - 221,027,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01216,037,977 - 216,163,020 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
GREM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11221,023,212 - 221,148,149 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1221,026,605 - 221,027,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01216,037,977 - 216,163,020 (-)NCBIMhudiblu_PPA_v0panPan3
GREM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1240,489,573 - 240,612,155 (-)EnsemblGRCh38hg38GRCh38
GRCh381240,489,573 - 240,612,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371240,652,873 - 240,775,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361238,719,496 - 238,842,085 (-)NCBINCBI36hg18NCBI36
Build 341236,979,833 - 237,101,430NCBI
Celera1213,908,963 - 214,031,592 (-)NCBI
Cytogenetic Map1q43NCBI
HuRef1211,110,745 - 211,233,432 (-)NCBIHuRef
CHM1_11241,924,855 - 242,047,766 (-)NCBICHM1_1
Grem2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,661,351 - 174,749,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1174,661,351 - 174,749,385 (-)Ensembl
GRCm381174,833,785 - 174,921,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,833,785 - 174,921,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,763,916 - 176,851,950 (-)NCBIGRCm37mm9NCBIm37
MGSCv361176,670,460 - 176,758,494 (-)NCBImm8
Celera1181,920,779 - 182,009,726 (-)NCBICelera
Cytogenetic Map1H3NCBI
Grem2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21386,778,543 - 86,871,509 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1386,778,500 - 86,871,615 (-)Ensembl
Rnor_6.01392,894,431 - 92,988,137 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1392,894,431 - 92,988,137 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01397,359,449 - 97,453,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41390,528,920 - 90,622,303 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1386,379,414 - 86,472,331 (-)NCBICelera
Cytogenetic Map13q24NCBI
Grem2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540611,245,960 - 11,343,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540611,245,960 - 11,343,677 (+)NCBIChiLan1.0ChiLan1.0
GREM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1732,048,151 - 32,157,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl732,048,183 - 32,157,146 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha731,588,241 - 31,697,847 (-)NCBI
ROS_Cfam_1.0731,872,605 - 31,982,246 (-)NCBI
UMICH_Zoey_3.1731,710,419 - 31,820,007 (-)NCBI
UNSW_CanFamBas_1.0731,741,770 - 31,851,741 (-)NCBI
UU_Cfam_GSD_1.0731,980,916 - 32,090,573 (-)NCBI
Grem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934444,922,948 - 45,027,019 (-)NCBI
SpeTri2.0NW_0049365269,820,276 - 9,821,907 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GREM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1011,885,280 - 11,885,780 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11011,884,198 - 11,904,249 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21014,102,376 - 14,122,799 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GREM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12577,600,306 - 77,724,090 (-)NCBI
ChlSab1.1 Ensembl2577,602,803 - 77,603,309 (-)Ensembl
Vero_WHO_p1.0NW_02366605579,707,875 - 79,832,479 (-)NCBI
Grem2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477110,965,170 - 11,072,462 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003824523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000012051   ⟹   ENSPPAP00000002506
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1221,026,605 - 221,027,111 (-)Ensembl
RefSeq Acc Id: XM_003824523   ⟹   XP_003824571
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11221,023,212 - 221,148,149 (-)NCBI
Mhudiblu_PPA_v01216,037,977 - 216,163,020 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003824571 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003824571   ⟸   XM_003824523
- Sequence:
RefSeq Acc Id: ENSPPAP00000002506   ⟸   ENSPPAT00000012051


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000011100 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000002506 ENTREZGENE
NCBI Gene GREM2 ENTREZGENE