IRF3 (interferon regulatory factor 3)

Gene: IRF3 (interferon regulatory factor 3) Pan paniscus

Analyze

Symbol:

IRF3

Name:

interferon regulatory factor 3

RGD ID:

11805142

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein domain specific binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); cellular response to exogenous dsRNA (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH asthma (ortholog); bacterial pneumonia (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,776,859 - 55,783,043 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,697,602 - 57,703,818 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,464 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,593,627 - 55,599,903 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,593,627 - 55,599,903 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

bacterial pneumonia (ISO)

developmental and epileptic encephalopathy 12 (ISO)

genetic disease (ISO)

Herpes Simplex Encephalitis (ISO)

Herpes Simplex Encephalitis 7 (ISO)

multisystem inflammatory syndrome in children (ISO)

Respiratory Tract Infections (ISO)

severe acute respiratory syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antiviral innate immune response (ISO)

cellular response to exogenous dsRNA (ISO)

cellular response to lipopolysaccharide (IEA,ISO)

cellular response to virus (IEA)

cytoplasmic pattern recognition receptor signaling pathway (ISO)

defense response to virus (IEA,ISO)

immune system process (IEA)

lipopolysaccharide-mediated signaling pathway (IEA,ISO)

mRNA transcription (ISO)

negative regulation of transcription by RNA polymerase II (IEA)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of cytokine production (ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of interferon-alpha production (IEA)

positive regulation of interferon-beta production (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

positive regulation of type I interferon production (ISO)

positive regulation of type I interferon-mediated signaling pathway (IEA,ISO)

programmed necrotic cell death (IEA,ISO)

regulation of apoptotic process (ISO)

regulation of DNA-templated transcription (IEA)

regulation of gene expression (IEA,ISO)

regulation of inflammatory response (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA)

response to bacterium (IEA,ISO)

response to exogenous dsRNA (IEA,ISO)

response to lipopolysaccharide (IEA,ISO)

toll-like receptor 4 signaling pathway (ISO)

TRIF-dependent toll-like receptor signaling pathway (ISO)

type I interferon-mediated signaling pathway (IEA)

Cellular Component

chromatin (ISO)

cytoplasm (ISO)

cytosol (ISO)

mitochondrion (ISO)

nucleus (IEA,ISO)

Molecular Function

DNA-binding transcription activator activity (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

identical protein binding (IEA)

promoter-specific chromatin binding (IEA)

protein binding (ISO)

protein domain specific binding (ISO)

protein homodimerization activity (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

transcription cis-regulatory region binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Toll-like receptor signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

IRF3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,776,859 - 55,783,043 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,697,602 - 57,703,818 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,464 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,593,627 - 55,599,903 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,593,627 - 55,599,903 (-)	Ensembl	panpan1.1		panPan2

IRF3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,659,572 - 49,665,857 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,659,569 - 49,665,875 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,162,829 - 50,169,114 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,854,641 - 54,860,936 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	54,854,641 - 54,860,926	NCBI
Celera	19	47,032,161 - 47,038,466 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,539,596 - 46,545,904 (-)	NCBI		HuRef
CHM1_1	19	50,164,615 - 50,170,921 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,659,601 - 52,665,933 (-)	NCBI		T2T-CHM13v2.0

Irf3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,647,072 - 44,652,272 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,647,072 - 44,652,272 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,997,648 - 45,002,848 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,997,648 - 45,002,848 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,253,030 - 52,258,218 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,865,702 - 44,870,890 (+)	NCBI		MGSCv36	mm8
Celera	7	40,449,220 - 40,454,417 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.07	NCBI

Irf3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,616,608 - 104,621,402 (+)	NCBI		GRCr8
mRatBN7.2	1	95,479,966 - 95,484,926 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,479,821 - 95,484,935 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,865,527 - 100,870,321 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,338,193 - 109,342,987 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,628,586 - 102,633,382 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,992,244 - 100,997,202 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,992,405 - 100,997,198 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,056,847 - 102,061,805 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,470,284 - 95,475,078 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	89,741,455 - 89,746,249 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Irf3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,224,874 - 1,228,624 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,223,986 - 1,228,671 (+)	NCBI	ChiLan1.0	ChiLan1.0

IRF3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,875,016 - 106,879,065 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,875,118 - 106,879,065 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,457,016 - 106,462,843 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,394,678 - 107,400,508 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,394,687 - 107,400,506 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,066,914 - 107,072,739 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,709,002 - 106,714,828 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,550,123 - 107,555,958 (+)	NCBI		UU_Cfam_GSD_1.0

Irf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,859,560 - 21,863,357 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,475,543 - 3,481,533 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,477,750 - 3,482,489 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRF3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,701,668 - 54,707,151 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,701,733 - 54,706,079 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,430,689 - 50,441,627 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IRF3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,835,285 - 42,841,487 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,831,203 - 42,840,796 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,779,185 - 22,785,813 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Irf3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,612,374 - 4,616,276 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,611,445 - 4,616,319 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008966956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008966962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008966963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034944575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034944578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034944579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034944580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055103339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055103340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063600503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010110919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010110920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010110921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000048078 ⟹ ENSPPAP00000025251

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,627 - 55,599,903 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048081 ⟹ ENSPPAP00000025254

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,627 - 55,599,903 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048089 ⟹ ENSPPAP00000025262

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,627 - 55,599,197 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048093 ⟹ ENSPPAP00000025266

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,647 - 55,598,866 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048096 ⟹ ENSPPAP00000025269

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,647 - 55,596,616 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048099 ⟹ ENSPPAP00000025272

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,593,706 - 55,598,866 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048101 ⟹ ENSPPAP00000025274

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,596,568 - 55,598,866 (-)	Ensembl

RefSeq Acc Id:

XM_008966956 ⟹ XP_008965204

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,112 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,784 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,464 (-)	NCBI
PanPan1.1	19	55,593,627 - 55,599,903 (-)	NCBI

Sequence:

show sequence

GGAAACCCAAAAAAGGGCATAGGGGCGGGAACAGCCCAGCGGGCCGTCCCATCGGCTTTCGGGT
CTGTTACCCAAAGAATGATAAAGTTGGTTTTATTTCAAGAAGTCGATCGAAAAGAAAGCCCCAG
CGCTCTAGAGCTCAGCTGACGGGAAAGGGGGTGCGCAGCCTCGAGTTTGAGAGCTACCCGGAGC
TCCAAGACAGGGGTGGGTTCCAGCTGCCCGCGCGCCCCGACCTTCCATCGTAGGCCGGACCATG
GGAACCCCAAAGCCACGGATCCTGCCCTGGCTGGTGTCGCAGCTGGACCTGGGGCAACTGGAGG
GCGTGGCCTGGGTGAACAAGAGCCGCACGCGCTTCCGCATCCCTTGGAAGCACGGCCTACGGCA
GGATGCACAGCAGGAGGATTTCGGAATCTTCCAGGCCTGGGCCGAGGCCACTGGCGCATATGTT
CCCGGGAGGGATAAGCCAGACCTGCCAACCTGGAAGAGGAATTTCCGCTCTGCCCTCAACCGCA
AAGAAGGGCTGCGCTTAGCAGAGGACCGGAGCAAGGACCCTCACGACCCACATAAAATCTACGA
GTTTGTGAACTCAGGAGTTGGGGACTTTTCCCAGCCAGACACCTCTCCGGACACCAATGGTGGA
GGCAGTACTTCTGATACCCAGGAAGACATTCTGGATGAGTTACTGGGTAACATGGTGTTGGCCC
CACTCCCAGATCCGGGACCCCCAAGCCTGGCTGTAGCCCCTGAGCCCTGCCCTCAGCCCCTGCG
GAGCCCCAGCTTGGACAATCCCACTCCCTTCCCAAACCTGGGGCCCTCTGAGAACCCACTGAAG
CGGCTGTTGGTACCGGGGGAAGAGTGGGAGTTCGAGGTGACAGCCTTCTACCGGGGCCGCCAAG
TCTTCCAGCAGACCATCTCCTGCCCAGAGGGCCTGCGGCTGGTGGGGTCCGAAGTGGGAGACAG
GACGCTGCCTGGATGGCCAGTCACACTGCCAGACCCTGGCATGTCCCTGACAGACAGGGGAGTG
ATGAGCTACGTGAGGCATGTGCTGAGCTGCCTGGGTGGGGGACTGGCTCTCTGGCGGGCCGGGC
AGTGGCTCTGGGCCCAGCGGCTGGGGCACTGCCACACATACTGGGCAGTGAGCGAGGAGCTGCT
CCCCAACAGCGGGCATGGGCCTGATGGCGAGGTCCCCAAGGACAAGGAAGGAGGCGTGTTTGAC
CTGGGGCCCTTCATTGTAGGCTCCTGGGCCCCCAGATCTGATTACCTTCACGGAAGGAAGCGGA
CGCTCACCACGCTATGCCCTCTGGTTCTGTGTGGGGGAATCATGGCCCCAGGACCAGCCGTGGA
CCAAGAGGCTCGTGATGGTCAAGGTTGTGCCCACGTGCCTCAGGGCCTTGGTAGAAATGGCCCG
GGTAGGGGGTGCCTCCTCCCTGGAGAACACTGTGGACCTGCACATTTCCAACAGCCACCCACTC
TCCCTCACCTCCGACCAGTACAAGGCCTACCTGCAGGACTTGGTGGAGGGCATGGATTTCCAGG
GCCCTGGGGAGACCTGAGCCCTCGTTCCTCATGGTGTGCCTGCAACCCCCCTGTTCCCCACCAC
CTCAACCAATAAACTGGTTCCTGCTATGATCA

hide sequence

RefSeq Acc Id:

XM_008966962 ⟹ XP_008965210

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,781,803 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,702,542 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,679,149 (-)	NCBI
PanPan1.1	19	55,593,627 - 55,598,560 (-)	NCBI

Sequence:

show sequence

AGGGGCGGGGCTAGCCGGATCAGCTGACTGATGGTGGGGCGCAAGCAGGGTTGGAGCTGCAGGG
TTACGGGAATAAAACCGGGAAAGCCGGCCTGGGCCGAGGCCACTGGCGCATATGTTCCCGGGAG
GGATAAGCCAGACCTGCCAACCTGGAAGAGGAATTTCCGCTCTGCCCTCAACCGCAAAGAAGGG
CTGCGCTTAGCAGAGGACCGGAGCAAGGACCCTCACGACCCACATAAAATCTACGAGTTTGTGA
ACTCAGGAGTTGGGGACTTTTCCCAGCCAGACACCTCTCCGGACACCAATGGTGGAGGCAGTAC
TTCTGATACCCAGGAAGACATTCTGGATGAGTTACTGGGTAACATGGTGTTGGCCCCACTCCCA
GATCCGGGACCCCCAAGCCTGGCTGTAGCCCCTGAGCCCTGCCCTCAGCCCCTGCGGAGCCCCA
GCTTGGACAATCCCACTCCCTTCCCAAACCTGGGGCCCTCTGAGAACCCACTGAAGCGGCTGTT
GGTACCGGGGGAAGAGTGGGAGTTCGAGGTGACAGCCTTCTACCGGGGCCGCCAAGTCTTCCAG
CAGACCATCTCCTGCCCAGAGGGCCTGCGGCTGGTGGGGTCCGAAGTGGGAGACAGGACGCTGC
CTGGATGGCCAGTCACACTGCCAGACCCTGGCATGTCCCTGACAGACAGGGGAGTGATGAGCTA
CGTGAGGCATGTGCTGAGCTGCCTGGGTGGGGGACTGGCTCTCTGGCGGGCCGGGCAGTGGCTC
TGGGCCCAGCGGCTGGGGCACTGCCACACATACTGGGCAGTGAGCGAGGAGCTGCTCCCCAACA
GCGGGCATGGGCCTGATGGCGAGGTCCCCAAGGACAAGGAAGGAGGCGTGTTTGACCTGGGGCC
CTTCATTGTAGGCTCCTGGGCCCCCAGATCTGATTACCTTCACGGAAGGAAGCGGACGCTCACC
ACGCTATGCCCTCTGGTTCTGTGTGGGGGAATCATGGCCCCAGGACCAGCCGTGGACCAAGAGG
CTCGTGATGGTCAAGGTTGTGCCCACGTGCCTCAGGGCCTTGGTAGAAATGGCCCGGGTAGGGG
GTGCCTCCTCCCTGGAGAACACTGTGGACCTGCACATTTCCAACAGCCACCCACTCTCCCTCAC
CTCCGACCAGTACAAGGCCTACCTGCAGGACTTGGTGGAGGGCATGGATTTCCAGGGCCCTGGG
GAGACCTGAGCCCTCGTTCCTCATGGTGTGCCTGCAACCCCCCTGTTCCCCACCACCTCAACCA
ATAAACTGGTTCCTGCTATGATCA

hide sequence

RefSeq Acc Id:

XM_008966963 ⟹ XP_008965211

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,783,043 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,782 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,464 (-)	NCBI
PanPan1.1	19	55,593,627 - 55,599,903 (-)	NCBI

Sequence:

show sequence

GGAAACCCAAAAAAGGGCATAGGGGCGGGAACAGCCCAGCGGGCCGTCCCATCGGCTTTCGGGT
CTGTTACCCAAAGAATGATAAAGTTGGTTTTATTTCAAGAAGTCGATCGAAAAGAAAGCCCCAG
CGCTCTAGAGCTCAGCTGACGGGAAAGGGGGTGCGCAGCCTCGAGTTTGAGAGCTACCCGGAGC
TCCAAGACAGGGGTGGGTTCCAGCTGCCCGCGCGCCCCGACCTTCCATCGTAGGTGCGTGCGAC
GACCTGGGACGCTGGAAACCCGGAGCTGCGCGCTGGGCGGAAAGGACTCCTAGTGGGCCCGGCT
GAGAAGGCGGAGGTGGCGCGCGAGGGGCGGGCTCGTGCCAACGCCGGTGGGTGGGGCTAGAACG
GGAGGGGCGGGGCTAGCCGGATCAGCTGACTGATGGTGGGGCGCAAGCAGGGTTGGAGCTGCAG
GGTTACGGGAATAAAACCGGGAAAGCCGGCCTGGGCCGAGGCCACTGGCGCATATGTTCCCGGG
AGGGATAAGCCAGACCTGCCAACCTGGAAGAGGAATTTCCGCTCTGCCCTCAACCGCAAAGAAG
GGCTGCGCTTAGCAGAGGACCGGAGCAAGGACCCTCACGACCCACATAAAATCTACGAGTTTGT
GAACTCAGGAGTTGGGGACTTTTCCCAGCCAGACACCTCTCCGGACACCAATGGTGGAGGCAGT
ACTTCTGATACCCAGGAAGACATTCTGGATGAGTTACTGGGTAACATGGTGTTGGCCCCACTCC
CAGATCCGGGACCCCCAAGCCTGGCTGTAGCCCCTGAGCCCTGCCCTCAGCCCCTGCGGAGCCC
CAGCTTGGACAATCCCACTCCCTTCCCAAACCTGGGGCCCTCTGAGAACCCACTGAAGCGGCTG
TTGGTACCGGGGGAAGAGTGGGAGTTCGAGGTGACAGCCTTCTACCGGGGCCGCCAAGTCTTCC
AGCAGACCATCTCCTGCCCAGAGGGCCTGCGGCTGGTGGGGTCCGAAGTGGGAGACAGGACGCT
GCCTGGATGGCCAGTCACACTGCCAGACCCTGGCATGTCCCTGACAGACAGGGGAGTGATGAGC
TACGTGAGGCATGTGCTGAGCTGCCTGGGTGGGGGACTGGCTCTCTGGCGGGCCGGGCAGTGGC
TCTGGGCCCAGCGGCTGGGGCACTGCCACACATACTGGGCAGTGAGCGAGGAGCTGCTCCCCAA
CAGCGGGCATGGGCCTGATGGCGAGGTCCCCAAGGACAAGGAAGGAGGCGTGTTTGACCTGGGG
CCCTTCATTGTAGATCTGATTACCTTCACGGAAGGAAGCGGACGCTCACCACGCTATGCCCTCT
GGTTCTGTGTGGGGGAATCATGGCCCCAGGACCAGCCGTGGACCAAGAGGCTCGTGATGGTCAA
GGTTGTGCCCACGTGCCTCAGGGCCTTGGTAGAAATGGCCCGGGTAGGGGGTGCCTCCTCCCTG
GAGAACACTGTGGACCTGCACATTTCCAACAGCCACCCACTCTCCCTCACCTCCGACCAGTACA
AGGCCTACCTGCAGGACTTGGTGGAGGGCATGGATTTCCAGGGCCCTGGGGAGACCTGAGCCCT
CGTTCCTCATGGTGTGCCTGCAACCCCCCTGTTCCCCACCACCTCAACCAATAAACTGGTTCCT
GCTATGATCA

hide sequence

RefSeq Acc Id:

XM_034944575 ⟹ XP_034800466

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,939 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,629 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,218 (-)	NCBI

RefSeq Acc Id:

XM_034944578 ⟹ XP_034800469

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,112 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,784 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,423 (-)	NCBI

RefSeq Acc Id:

XM_034944579 ⟹ XP_034800470

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,112 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,784 (-)	NCBI
Mhudiblu_PPA_v0	19	46,674,193 - 46,680,374 (-)	NCBI

RefSeq Acc Id:

XM_055103339 ⟹ XP_054959314

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,112 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,817 (-)	NCBI

RefSeq Acc Id:

XM_055103340 ⟹ XP_054959315

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,782,112 (-)	NCBI
NHGRI_mPanPan1	19	57,697,602 - 57,703,784 (-)	NCBI

RefSeq Acc Id:

XM_063600503 ⟹ XP_063456573

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,776,859 - 55,781,803 (-)	NCBI

RefSeq Acc Id:

XR_010110919

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,778,026 - 55,782,112 (-)	NCBI

RefSeq Acc Id:

XR_010110920

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,778,026 - 55,782,112 (-)	NCBI

RefSeq Acc Id:

XR_010110921

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,778,026 - 55,782,112 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008965204	(Get FASTA)	NCBI Sequence Viewer
	XP_008965210	(Get FASTA)	NCBI Sequence Viewer
	XP_008965211	(Get FASTA)	NCBI Sequence Viewer
	XP_034800466	(Get FASTA)	NCBI Sequence Viewer
	XP_034800469	(Get FASTA)	NCBI Sequence Viewer
	XP_034800470	(Get FASTA)	NCBI Sequence Viewer
	XP_054959314	(Get FASTA)	NCBI Sequence Viewer
	XP_054959315	(Get FASTA)	NCBI Sequence Viewer
	XP_063456573	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000025251
	ENSPPAP00000025251.1
	ENSPPAP00000025254
	ENSPPAP00000025254.1
	ENSPPAP00000025262.1
	ENSPPAP00000025266.1
	ENSPPAP00000025269.1
	ENSPPAP00000025272.1
	ENSPPAP00000025274.1

RefSeq Acc Id:	XP_008965211 ⟸ XM_008966963
- Peptide Label:	isoform X8
- UniProtKB:	A0A2R9B856 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVGRKQGWSCRVTGIKPGKPAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD PHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVA PEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLR LVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHT YWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQD QPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGM DFQGPGET hide sequence

RefSeq Acc Id:	XP_008965204 ⟸ XM_008966956
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9BDU3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAY VPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNG GGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPL KRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRG VMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVF DLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGIMAPGPAVDQEARDGQGCAHVPQGLGRNG PGRGCLLPGEHCGPAHFQQPPTLPHLRPVQGLPAGLGGGHGFPGPWGDLSPRSSWCACNPPVPH HLNQ hide sequence

RefSeq Acc Id:

XP_008965210 ⟸ XM_008966962

- Peptide Label:

isoform X6

- Sequence:

show sequence

MVGRKQGWSCRVTGIKPGKPAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD
PHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVA
PEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLR
LVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHT
YWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGG
IMAPGPAVDQEARDGQGCAHVPQGLGRNGPGRGCLLPGEHCGPAHFQQPPTLPHLRPVQGLPAG
LGGGHGFPGPWGDLSPRSSWCACNPPVPHHLNQ

hide sequence

RefSeq Acc Id:	XP_034800469 ⟸ XM_034944578
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_034800470 ⟸ XM_034944579
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_034800466 ⟸ XM_034944575
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSPPAP00000025251 ⟸ ENSPPAT00000048078

RefSeq Acc Id:

ENSPPAP00000025254 ⟸ ENSPPAT00000048081

RefSeq Acc Id:

ENSPPAP00000025262 ⟸ ENSPPAT00000048089

RefSeq Acc Id:

ENSPPAP00000025269 ⟸ ENSPPAT00000048096

RefSeq Acc Id:

ENSPPAP00000025272 ⟸ ENSPPAT00000048099

RefSeq Acc Id:

ENSPPAP00000025266 ⟸ ENSPPAT00000048093

RefSeq Acc Id:

ENSPPAP00000025274 ⟸ ENSPPAT00000048101

RefSeq Acc Id:	XP_054959314 ⟸ XM_055103339
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9B6Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054959315 ⟸ XM_055103340
- Peptide Label:	isoform X7
- UniProtKB:	A0A2R9B871 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063456573 ⟸ XM_063600503
- Peptide Label:	isoform X9

Protein Domains

IRF tryptophan pentad repeat

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000035759	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000048078.1	UniProtKB/TrEMBL
	ENSPPAT00000048081.1	UniProtKB/TrEMBL
	ENSPPAT00000048089.1	UniProtKB/TrEMBL
	ENSPPAT00000048093.1	UniProtKB/TrEMBL
	ENSPPAT00000048096.1	UniProtKB/TrEMBL
	ENSPPAT00000048099.1	UniProtKB/TrEMBL
	ENSPPAT00000048101.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.60.200.10	UniProtKB/TrEMBL
InterPro	Interferon_reg_fac_CS	UniProtKB/TrEMBL
	Interferon_reg_fact_DNA-bd_dom	UniProtKB/TrEMBL
	Interferon_reg_factor-3	UniProtKB/TrEMBL
	SMAD-like_dom_sf	UniProtKB/TrEMBL
	SMAD_FHA_dom_sf	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	pps:100977114	UniProtKB/TrEMBL
NCBI Gene	IRF3	ENTREZGENE
PANTHER	INTERFERON REGULATORY FACTOR	UniProtKB/TrEMBL
	INTERFERON REGULATORY FACTOR 3	UniProtKB/TrEMBL
Pfam	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
PRINTS	INTFRNREGFCT	UniProtKB/TrEMBL
PROSITE	IRF_1	UniProtKB/TrEMBL
	IRF_2	UniProtKB/TrEMBL
SMART	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF49879	UniProtKB/TrEMBL
UniProt	A0A2R9B6Q3	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B6R1_PANPA	UniProtKB/TrEMBL
	A0A2R9B856	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B871	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BDU3	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BDV5_PANPA	UniProtKB/TrEMBL
	A0A2R9BDY8_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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