CANX (calnexin) - Rat Genome Database

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Gene: CANX (calnexin) Pan paniscus
Analyze
Symbol: CANX
Name: calnexin
RGD ID: 11800596
Description: ENCODES a protein that exhibits apolipoprotein binding (ortholog); ionotropic glutamate receptor binding (ortholog); INVOLVED IN clathrin-dependent endocytosis (inferred); protein folding (inferred); synaptic vesicle endocytosis (inferred); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 1 (ortholog); FOUND IN axon (ortholog); dendrite cytoplasm (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,621,670 - 174,673,516 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,761,209 - 172,813,055 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,832,964 - 174,884,804 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,166,982 - 182,197,403 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,167,012 - 182,197,403 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CANX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,621,670 - 174,673,516 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,761,209 - 172,813,055 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,832,964 - 174,884,804 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,166,982 - 182,197,403 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,167,012 - 182,197,403 (+)Ensemblpanpan1.1panPan2
CANX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,678,656 - 179,731,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,678,628 - 179,731,641 (+)EnsemblGRCh38hg38GRCh38
GRCh375179,125,428 - 179,158,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,058,536 - 179,091,248 (+)NCBINCBI36Build 36hg18NCBI36
Build 345179,058,601 - 179,090,532NCBI
Celera5174,751,027 - 174,783,690 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,852,686 - 173,884,832 (+)NCBIHuRef
CHM1_15178,558,332 - 178,591,063 (+)NCBICHM1_1
T2T-CHM13v2.05180,233,830 - 180,286,826 (+)NCBIT2T-CHM13v2.0
Canx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,184,784 - 50,216,500 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,184,788 - 50,216,500 (-)EnsemblGRCm39 Ensembl
GRCm381150,293,957 - 50,325,673 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,293,961 - 50,325,673 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,107,459 - 50,139,175 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,137,890 - 50,169,014 (-)NCBIMGSCv36mm8
Celera1154,854,566 - 54,886,282 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.46NCBI
Canx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,124,941 - 35,157,954 (-)NCBIGRCr8
mRatBN7.21034,623,865 - 34,656,866 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,625,191 - 34,656,821 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,295,127 - 39,328,327 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,834,377 - 7,867,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,288,797 - 34,322,002 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,800,942 - 35,833,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,800,942 - 35,833,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,562,608 - 35,595,530 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,850,944 - 35,883,494 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,855,099 - 35,870,453 (-)NCBI
Celera1033,972,278 - 34,005,640 (-)NCBICelera
Cytogenetic Map10q22NCBI
Canx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955408848,808 - 894,362 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955408850,773 - 894,362 (-)NCBIChiLan1.0ChiLan1.0
CANX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,966,612 - 1,998,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,927,888 - 1,998,604 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,089,958 - 2,121,930 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,940,260 - 1,973,222 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl111,940,276 - 1,973,226 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,912,686 - 1,944,662 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0111,991,514 - 2,023,492 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,232,031 - 2,264,021 (-)NCBIUU_Cfam_GSD_1.0
Canx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,842,076 - 119,892,055 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,051,240 - 1,086,405 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,051,853 - 1,085,658 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CANX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,879,033 - 78,915,827 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1278,879,031 - 78,915,828 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2280,445,609 - 80,482,509 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CANX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,422,701 - 81,454,683 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2381,422,693 - 81,482,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607512,804,176 - 12,829,375 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Canx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473342,588,680 - 42,616,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044566   ⟹   ENSPPAP00000021763
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5182,167,012 - 182,197,403 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044575   ⟹   ENSPPAP00000021772
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5182,174,195 - 182,176,749 (+)Ensembl
RefSeq Acc Id: XM_003809203   ⟹   XP_003809251
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,641,716 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,781,262 - 172,813,055 (+)NCBI
Mhudiblu_PPA_v05174,852,864 - 174,884,804 (+)NCBI
PanPan1.15182,166,982 - 182,197,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003809204   ⟹   XP_003809252
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,641,687 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,781,226 - 172,813,055 (+)NCBI
Mhudiblu_PPA_v05174,852,841 - 174,884,804 (+)NCBI
PanPan1.15182,166,988 - 182,197,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008961400   ⟹   XP_008959648
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,641,481 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,781,020 - 172,813,055 (+)NCBI
Mhudiblu_PPA_v05174,852,853 - 174,884,804 (+)NCBI
PanPan1.15182,167,016 - 182,197,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034961197   ⟹   XP_034817088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,621,670 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,761,209 - 172,813,055 (+)NCBI
Mhudiblu_PPA_v05174,832,964 - 174,884,804 (+)NCBI
RefSeq Acc Id: XM_055112906   ⟹   XP_054968881
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,621,676 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,761,215 - 172,813,055 (+)NCBI
RefSeq Acc Id: XM_055112907   ⟹   XP_054968882
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,641,880 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,781,419 - 172,813,055 (+)NCBI
RefSeq Acc Id: XM_055112908   ⟹   XP_054968883
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,637,396 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,776,935 - 172,813,055 (+)NCBI
RefSeq Acc Id: XM_055112909   ⟹   XP_054968884
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,631,639 - 174,673,516 (+)NCBI
NHGRI_mPanPan15172,771,178 - 172,813,055 (+)NCBI
RefSeq Acc Id: XM_063604340   ⟹   XP_063460410
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,639,803 - 174,673,516 (+)NCBI
RefSeq Acc Id: XM_063604341   ⟹   XP_063460411
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24174,638,335 - 174,673,516 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003809251   ⟸   XM_003809203
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AWV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003809252   ⟸   XM_003809204
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AWV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008959648   ⟸   XM_008961400
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_034817088   ⟸   XM_034961197
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AWV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000021763   ⟸   ENSPPAT00000044566
RefSeq Acc Id: ENSPPAP00000021772   ⟸   ENSPPAT00000044575
RefSeq Acc Id: XP_054968881   ⟸   XM_055112906
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054968884   ⟸   XM_055112909
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054968883   ⟸   XM_055112908
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054968882   ⟸   XM_055112907
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063460411   ⟸   XM_063604341
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063460410   ⟸   XM_063604340
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044566.1 UniProtKB/TrEMBL
  ENSPPAT00000044575.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.250.10 UniProtKB/TrEMBL
  2.60.120.200 UniProtKB/TrEMBL
InterPro Calret/calnex UniProtKB/TrEMBL
  Calret/calnex_CS UniProtKB/TrEMBL
  Calreticulin/calnexin_P_dom_sf UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100980239 UniProtKB/TrEMBL
NCBI Gene CANX ENTREZGENE
PANTHER CALNEXIN UniProtKB/TrEMBL
  PTHR11073 UniProtKB/TrEMBL
Pfam Calreticulin UniProtKB/TrEMBL
PRINTS CALRETICULIN UniProtKB/TrEMBL
PROSITE CALRETICULIN_1 UniProtKB/TrEMBL
  CALRETICULIN_2 UniProtKB/TrEMBL
  CALRETICULIN_REPEAT UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
  SSF63887 UniProtKB/TrEMBL
UniProt A0A2R9AWV7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AX66_PANPA UniProtKB/TrEMBL