CYP4F3 (cytochrome P450 family 4 subfamily F member 3)

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Gene: CYP4F3 (cytochrome P450 family 4 subfamily F member 3) Pan paniscus

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Symbol:

CYP4F3

Name:

cytochrome P450 family 4 subfamily F member 3

RGD ID:

11798395

Description:

ENCODES a protein that exhibits 20-aldehyde-leukotriene B4 20-monooxygenase activity (ortholog); 20-hydroxy-leukotriene B4 omega oxidase activity (ortholog); leukotriene-B4 20-monooxygenase activity (ortholog); INVOLVED IN fatty acid omega-oxidation (ortholog); leukotriene B4 catabolic process (ortholog); leukotriene B4 metabolic process (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Poisoning (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cytochrome P450 4F2; cytochrome P450 4F3; docosahexaenoic acid omega-hydroxylase CYP4F3; leukotriene-B(4) omega-hydroxylase 2; LOC100969141; phylloquinone omega-hydroxylase CYP4F2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	20,545,248 - 20,566,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	19,548,098 - 19,568,193 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	15,162,886 - 15,182,334 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	16,146,664 - 16,165,869 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	16,146,664 - 16,165,869 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Poisoning (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arachidonate metabolic process (IEA)

fatty acid omega-oxidation (ISO)

leukotriene B4 catabolic process (ISO)

leukotriene B4 metabolic process (ISO)

lipoxin A4 metabolic process (ISO)

lipoxin B4 metabolic process (ISO)

menaquinone catabolic process (IEA)

omega-hydroxylase P450 pathway (ISO)

phylloquinone catabolic process (IEA)

Cellular Component

membrane (IEA)

Molecular Function

20-aldehyde-leukotriene B4 20-monooxygenase activity (ISO)

20-hydroxy-leukotriene B4 omega oxidase activity (ISO)

heme binding (IEA)

iron ion binding (IEA)

leukotriene-B4 20-monooxygenase activity (ISO)

long-chain fatty acid omega-1 hydroxylase activity (ISO)

long-chain fatty acid omega-hydroxylase activity (ISO)

metal ion binding (IEA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

very long-chain fatty acid omega-hydroxylase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylsalicylic acid pharmacodynamics pathway (ISO)

antipyrine drug pathway (ISO)

arachidonic acid metabolic pathway (ISO)

celecoxib pharmacodynamics pathway (ISO)

diclofenac pharmacodynamics pathway (ISO)

diflunisal pharmacodynamics pathway (ISO)

etodolac pharmacodynamics pathway (ISO)

fenoprofen pharmacodynamics pathway (ISO)

flurbiprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

indometacin pharmacodynamics pathway (ISO)

ketoprofen pharmacodynamics pathway (ISO)

ketorolac pharmacodynamics pathway (ISO)

leukotriene C4 synthase deficiency pathway (ISO)

lornoxicam pharmacodynamics pathway (ISO)

magnesium salicylate pharmacodynamics pathway (ISO)

mefenamic acid pharmacodynamics pathway (ISO)

meloxicam pharmacodynamics pathway (ISO)

nabumetone pharmacodynamics pathway (ISO)

naproxen pharmacodynamics pathway (ISO)

paracetamol drug pathway (ISO)

piroxicam pharmacodynamics pathway (ISO)

salicylic acid pharmacodynamics pathway (ISO)

sodium salicylate pharmacodynamics pathway (ISO)

sulindac pharmacodynamics pathway (ISO)

tenoxicam pharmacodynamics pathway (ISO)

tiaprofenic acid pharmacodynamics pathway (ISO)

tolmetin pharmacodynamics pathway (ISO)

valdecoxib pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CYP4F3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	20,545,248 - 20,566,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	19,548,098 - 19,568,193 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	15,162,886 - 15,182,334 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	16,146,664 - 16,165,869 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	16,146,664 - 16,165,869 (+)	Ensembl	panpan1.1		panPan2

CYP4F3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	15,640,897 - 15,662,825 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	15,640,897 - 15,662,825 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	15,751,707 - 15,773,635 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	15,612,707 - 15,632,570 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	15,612,706 - 15,634,634	NCBI
Celera	19	15,648,618 - 15,668,477 (+)	NCBI		Celera
Cytogenetic Map	19	p13.12	NCBI
HuRef	19	15,320,174 - 15,340,137 (+)	NCBI		HuRef
CHM1_1	19	15,751,200 - 15,771,063 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	15,766,167 - 15,788,209 (+)	NCBI		T2T-CHM13v2.0

Cyp4f18
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	72,742,326 - 72,763,512 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	72,742,326 - 72,763,470 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	71,988,482 - 72,009,668 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,988,482 - 72,009,626 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	74,512,381 - 74,533,525 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	74,917,471 - 74,938,606 (-)	NCBI		MGSCv36	mm8
Celera	8	76,344,833 - 76,358,866 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.67	NCBI

Cyp4f18
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	17,797,558 - 17,838,958 (+)	NCBI		GRCr8
mRatBN7.2	16	17,763,543 - 17,804,944 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	17,707,317 - 17,804,940 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	17,829,506 - 17,857,398 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	18,962,528 - 18,990,280 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	17,882,424 - 17,910,318 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	19,501,680 - 19,528,935 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	19,410,810 - 19,528,999 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	19,358,299 - 19,385,553 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	18,183,761 - 18,225,158 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	18,197,585 - 18,224,006 (+)	NCBI
Celera	16	17,986,320 - 18,013,579 (+)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

LOC484867
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	46,611,799 - 46,664,131 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	46,458,620 - 46,705,789 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	46,491,933 - 46,513,188 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	47,130,943 - 47,152,195 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	47,098,253 - 47,151,792 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	46,365,840 - 46,387,293 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	46,784,998 - 46,803,798 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	47,058,563 - 47,076,586 (-)	NCBI		UU_Cfam_GSD_1.0

LOC110259329
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	61,864,575 - 61,984,903 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	61,863,378 - 61,884,717 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CYP4F3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	14,241,352 - 14,260,799 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	14,241,409 - 14,263,494 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	5,238,620 - 5,257,739 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003813573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008966103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000052224 ⟹ ENSPPAP00000029375

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	16,146,664 - 16,165,869 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000052225 ⟹ ENSPPAP00000029376

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	16,146,665 - 16,165,869 (+)	Ensembl

RefSeq Acc Id:

XM_003813573 ⟹ XP_003813621

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	20,545,248 - 20,566,863 (+)	NCBI
NHGRI_mPanPan1	19	19,548,098 - 19,568,193 (+)	NCBI
Mhudiblu_PPA_v0	19	15,162,886 - 15,182,334 (+)	NCBI
PanPan1.1	19	16,146,665 - 16,165,869 (+)	NCBI

Sequence:

show sequence

TCCCAGAAGAAGGGGAGAGGAGGTTGTGTGGGACAAGGTGCTCCTGACAGAAGGATGCCACAGC
TGAGCCTGTCCTCGCTGGGCCTTTGGCCAATGGCAGCATCCCCGTGGCTGCTCCTGCTGCTGGT
CGGGGCCTCCTGGCTCCTGGCCTGCATCCTGGCCTGGACCTATACCTTCTATGACAACTTCCGT
CGCCTCCGGTGTTTCCCGCAACCCCCGAAACGGAATTGGTTCTTGGGTCACCTGGGCCTGGTCA
CCCCCACGGAGCAGGGCATGAGGGTCCTGACTCAGCTGGTGGCCACCTACCCCCAGGGCTTTAA
GGTCTGGATGGGCCCCATCTTCCCCGTCATCCATTTTTGCCACCCCAACATCATCCGGTCTGTC
ATCAACGCCTCAGCCGCCATTGTACCAAAGGACAAGGTCTTCTACAGCTTCCTGAAGCCCTGGC
TGGGGGATGGGCTCCTGCTGAGTGCTGGTGAAAAGTGGAGCCGCCACCGTCGGATGCTGACGCC
TGCCTTCCATTTCAACATCCTGAAGCCCTATATGAAGATTTTCAATGAGAGTGTGAACATCATG
CATGCCAAGTGGCAGCTCCTGGCCTCAGAGGGTAGTGCCCGTCTGGACATGTTTGAGCACATCA
GCCTCATGACCTTGGACAGTCTGCAGAAATGTGTCTTCAGCTTTGACAGCCATTGCCAGGAGAA
GCCCAGTGAATATATTGCCGCCATCTTGGAGCTCAGTGCCCTTGTGACAAAAAGACACCAGCAG
ATCCTCCTGTACATAGACTTCCTGTATTATCTCACCCATGATGGGCAGCGTTTCCGCAGGGCCT
GCCGCCTGGTGCACGACTTCACAGATGCCGTCATCCAGGAGCGGCGCCGCACCCTCCCTAGCCA
GGGTGTTGATGACTTCCTCCAAGCCAAGGCCAAGTCCAAGACTTTGGATTTCATTGATGTGCTC
CTGCTGAGCAAGGATGAAGATGGGAAGAAGTTGTCCGATGAGGACATAAGAGCAGAAGCTGACA
CCTTTATGTTTGAGGGCCATGACACCACGGCCAGTGGTCTCTCCTGGGTCCTGTACCACCTTGC
AAAGCACCCGGAATACCAGGAGCGCTGCCGGCAGGAGGTGCAAGAGCTTCTGAAGGACCGTGAG
CCTAAAGAGATTGAATGGGACGACCTGGCCCATTTGCCCTTCCTGACCATGTGCATGAAGGAGA
GCCTGCGGCTGCATCCCCCAGTCCCTGCCGTCTCTCGCTGCTGCACCCAAGACATTGTGCTCCC
AGACGGCCGGGTCATCCCCAAAGGCATTATCTGCCTCATCAGTGTTTTTGGAACCCATCACAAC
CCAGCCGTGTGGCCGGACCCTGAGGTCTATGATCCCTTTCGCTTTGACCCAAAGAACATCAAGG
AGAGGTCACCTCTGGCTTTTATTCCCTTCTCAGCAGGGCCCAGGAACTGCATCGGGCAGGCGTT
CGCGATGGCGGAGATGAAGGTGGTCCTGGGGCTCACGCTGCTGCGCTTCCGCGTCCTGCCTGAC
CACACCGAGCCCCGCAGGAAGCCGGAGCTGGTCCTGCGCGCAGAGGGCGGACTTTGGCTGCGGG
TGGAGCCCCTGAGCTGAGTTCTGCAGAGACCCACTCTGACCCCACTAAAATGACCCCTGATTCA
TCAAAAGTGAAGCCTAGAATTACCCTAAGACCCTGTTCCACAGTCCTGTATTCCATCCTAGATA
TCTACTCAAAATAATTGAGACAGGTGTTCAAACAGAAAGACGCTTGTGTGTGAATGTTCATGGC
AGCCCTATTCACAGTAGCCAAACGATGAAAACAACCCCAAAGTATATATTACCAGATGAAAGGA
TAAACAAAATGTGGTCCATCCATACAATGGAATATTACACAGCCATAAAAAGGAATGAAGCAGT
GATCCCTACTACACTGTGGATGAACCTTGAATGCATGATACTGAATGAAAGACGTCAGATGCAA
AAGGTCACATAGTGTACGGTCCTTTTATATGAAATTTCCAGAACAGGCCAATCTGAAGAGATGT
ATAGTGGATTGGTGGCTTTCAGCAGCTGTGGGGAGGTGGGACTGAGGAGCGACTGCTAATCAGG
ATGGGGTTTCCTCCTGGGATGGTGAAAATGTTCCGGACCTAGATAGTGACGAAGGTAGCATGAC
ACTGTCAGTGCACTAAATGCTATTGAATTGGACACTTTAGAATGGTTGAAATAGTGATTTTTAT
GTGAATTCTACCTAAACATGCTATTACAGCTCATATATACTTTTTCCATCTGGATTCTTCACAA
AAGAATATGTTGTGAGCATCTTTCCATGATATTAAATCATCTTAGGAAACATTA

hide sequence

RefSeq Acc Id:

XM_008966103 ⟹ XP_008964351

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	20,545,248 - 20,566,863 (+)	NCBI
NHGRI_mPanPan1	19	19,548,098 - 19,568,193 (+)	NCBI
Mhudiblu_PPA_v0	19	15,162,886 - 15,182,334 (+)	NCBI
PanPan1.1	19	16,146,664 - 16,165,869 (+)	NCBI

Sequence:

show sequence

CTCCCAGAAGAAGGGGAGAGGAGGTTGTGTGGGACAAGGTGCTCCTGACAGAAGGATGCCACAG
CTGAGCCTGTCCTCGCTGGGCCTTTGGCCAATGGCAGCATCCCCGTGGCTGCTCCTGCTGCTGG
TCGGGGCCTCCTGGCTCCTGGCCTGCATCCTGGCCTGGACCTATACCTTCTATGACAACTTCCG
TCGCCTCCGGTGTTTCCCGCAACCCCCGAAACGGAATTGGTTCTTGGGTCACCTGGGCCTGATT
CACAGCTCGGAGGAAGGTCTCCTATACACACAAAGCCTGGCATGCACCTTCGGTGATATGTGCT
GCTGGTGGGTGGGGCCCTGGCACGCAATCGTCCGCATCTTCCACCCCACCTACATCAAGCCTGT
GCTCTTTGCTCCAGCCGCCATTGTACCAAAGGACAAGGTCTTCTACAGCTTCCTGAAGCCCTGG
CTGGGGGATGGGCTCCTGCTGAGTGCTGGTGAAAAGTGGAGCCGCCACCGTCGGATGCTGACGC
CTGCCTTCCATTTCAACATCCTGAAGCCCTATATGAAGATTTTCAATGAGAGTGTGAACATCAT
GCATGCCAAGTGGCAGCTCCTGGCCTCAGAGGGTAGTGCCCGTCTGGACATGTTTGAGCACATC
AGCCTCATGACCTTGGACAGTCTGCAGAAATGTGTCTTCAGCTTTGACAGCCATTGCCAGGAGA
AGCCCAGTGAATATATTGCCGCCATCTTGGAGCTCAGTGCCCTTGTGACAAAAAGACACCAGCA
GATCCTCCTGTACATAGACTTCCTGTATTATCTCACCCATGATGGGCAGCGTTTCCGCAGGGCC
TGCCGCCTGGTGCACGACTTCACAGATGCCGTCATCCAGGAGCGGCGCCGCACCCTCCCTAGCC
AGGGTGTTGATGACTTCCTCCAAGCCAAGGCCAAGTCCAAGACTTTGGATTTCATTGATGTGCT
CCTGCTGAGCAAGGATGAAGATGGGAAGAAGTTGTCCGATGAGGACATAAGAGCAGAAGCTGAC
ACCTTTATGTTTGAGGGCCATGACACCACGGCCAGTGGTCTCTCCTGGGTCCTGTACCACCTTG
CAAAGCACCCGGAATACCAGGAGCGCTGCCGGCAGGAGGTGCAAGAGCTTCTGAAGGACCGTGA
GCCTAAAGAGATTGAATGGGACGACCTGGCCCATTTGCCCTTCCTGACCATGTGCATGAAGGAG
AGCCTGCGGCTGCATCCCCCAGTCCCTGCCGTCTCTCGCTGCTGCACCCAAGACATTGTGCTCC
CAGACGGCCGGGTCATCCCCAAAGGCATTATCTGCCTCATCAGTGTTTTTGGAACCCATCACAA
CCCAGCCGTGTGGCCGGACCCTGAGGTCTATGATCCCTTTCGCTTTGACCCAAAGAACATCAAG
GAGAGGTCACCTCTGGCTTTTATTCCCTTCTCAGCAGGGCCCAGGAACTGCATCGGGCAGGCGT
TCGCGATGGCGGAGATGAAGGTGGTCCTGGGGCTCACGCTGCTGCGCTTCCGCGTCCTGCCTGA
CCACACCGAGCCCCGCAGGAAGCCGGAGCTGGTCCTGCGCGCAGAGGGCGGACTTTGGCTGCGG
GTGGAGCCCCTGAGCTGAGTTCTGCAGAGACCCACTCTGACCCCACTAAAATGACCCCTGATTC
ATCAAAAGTGAAGCCTAGAATTACCCTAAGACCCTGTTCCACAGTCCTGTATTCCATCCTAGAT
ATCTACTCAAAATAATTGAGACAGGTGTTCAAACAGAAAGACGCTTGTGTGTGAATGTTCATGG
CAGCCCTATTCACAGTAGCCAAACGATGAAAACAACCCCAAAGTATATATTACCAGATGAAAGG
ATAAACAAAATGTGGTCCATCCATACAATGGAATATTACACAGCCATAAAAAGGAATGAAGCAG
TGATCCCTACTACACTGTGGATGAACCTTGAATGCATGATACTGAATGAAAGACGTCAGATGCA
AAAGGTCACATAGTGTACGGTCCTTTTATATGAAATTTCCAGAACAGGCCAATCTGAAGAGATG
TATAGTGGATTGGTGGCTTTCAGCAGCTGTGGGGAGGTGGGACTGAGGAGCGACTGCTAATCAG
GATGGGGTTTCCTCCTGGGATGGTGAAAATGTTCCGGACCTAGATAGTGACGAAGGTAGCATGA
CACTGTCAGTGCACTAAATGCTATTGAATTGGACACTTTAGAATGGTTGAAATAGTGATTTTTA
TGTGAATTCTACCTAAACATGCTATTACAGCTCATATATACTTTTTCCATCTGGATTCTTCACA
AAAGAATATGTTGTGAGCATCTTTCCATGATATTAAATCATCTTAGGAAACATTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003813621	(Get FASTA)	NCBI Sequence Viewer
	XP_008964351	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000006914.1
	ENSPPAP00000029375
	ENSPPAP00000029375.1
	ENSPPAP00000029376
	ENSPPAP00000029376.1

RefSeq Acc Id:	XP_008964351 ⟸ XM_008966103
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BI89 (UniProtKB/TrEMBL), A0A2R8ZVJ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPQLSLSSLGLWPMAASPWLLLLLVGASWLLACILAWTYTFYDNFRRLRCFPQPPKRNWFLGHL GLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFL KPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMF EHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTHDGQRF RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRA EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMC MKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPK NIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGL WLRVEPLS hide sequence

RefSeq Acc Id:	XP_003813621 ⟸ XM_003813573
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BS15 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPQLSLSSLGLWPMAASPWLLLLLVGASWLLACILAWTYTFYDNFRRLRCFPQPPKRNWFLGHL GLVTPTEQGMRVLTQLVATYPQGFKVWMGPIFPVIHFCHPNIIRSVINASAAIVPKDKVFYSFL KPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMF EHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTHDGQRF RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRA EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMC MKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPK NIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGL WLRVEPLS hide sequence

Ensembl Acc Id:

ENSPPAP00000029376 ⟸ ENSPPAT00000052225

Ensembl Acc Id:

ENSPPAP00000029375 ⟸ ENSPPAT00000052224

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000025911	UniProtKB/TrEMBL
	ENSPPAG00000037690	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000028766.1	UniProtKB/TrEMBL
	ENSPPAT00000052224.1	UniProtKB/TrEMBL
	ENSPPAT00000052225.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
	Cytochrome_P450_Monoox	UniProtKB/TrEMBL
KEGG Report	pps:100969141	UniProtKB/TrEMBL
NCBI Gene	LOC100969141	ENTREZGENE
PANTHER	CYTOCHROME P450 4F2	UniProtKB/TrEMBL
	CYTOCHROME P450 4F3	UniProtKB/TrEMBL
	CYTOCHROME P450 FAMILY 4	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A0A2R8ZVJ8	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BI89	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BS15	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:83062	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-02-25	CYP4F3	cytochrome P450 family 4 subfamily F member 3	LOC100969141	docosahexaenoic acid omega-hydroxylase CYP4F3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - CTD

Imported Annotations - SMPDB