BMP3 (bone morphogenetic protein 3) - Rat Genome Database

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Gene: BMP3 (bone morphogenetic protein 3) Pan paniscus
Analyze
Symbol: BMP3
Name: bone morphogenetic protein 3
RGD ID: 11793607
Description: ENCODES a protein that exhibits growth factor activity (ortholog); INVOLVED IN negative regulation of ossification (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Tibial Fractures (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2349,012,023 - 49,039,117 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1449,200,736 - 49,227,920 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0443,143,784 - 43,170,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1448,992,172 - 49,018,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl448,992,266 - 49,019,205 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BMP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2349,012,023 - 49,039,117 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1449,200,736 - 49,227,920 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0443,143,784 - 43,170,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1448,992,172 - 49,018,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl448,992,266 - 49,019,205 (-)Ensemblpanpan1.1panPan2
BMP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38481,030,708 - 81,057,627 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl481,030,708 - 81,057,627 (+)EnsemblGRCh38hg38GRCh38
GRCh37481,951,862 - 81,978,781 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36482,171,143 - 82,197,709 (+)NCBINCBI36Build 36hg18NCBI36
Build 34482,309,297 - 82,331,904NCBI
Celera479,245,158 - 79,271,726 (+)NCBICelera
Cytogenetic Map4q21.21NCBI
HuRef477,696,010 - 77,722,586 (+)NCBIHuRef
CHM1_1481,928,619 - 81,955,186 (+)NCBICHM1_1
T2T-CHM13v2.0484,360,741 - 84,387,664 (+)NCBIT2T-CHM13v2.0
Bmp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39599,002,274 - 99,031,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl599,002,274 - 99,032,255 (+)EnsemblGRCm39 Ensembl
GRCm38598,854,415 - 98,884,053 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl598,854,415 - 98,884,396 (+)EnsemblGRCm38mm10GRCm38
MGSCv37599,283,458 - 99,309,979 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36599,094,741 - 99,120,430 (+)NCBIMGSCv36mm8
Celera596,176,773 - 96,203,304 (+)NCBICelera
Cytogenetic Map5E3NCBI
cM Map548.24NCBI
Bmp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81411,012,564 - 11,041,282 (-)NCBIGRCr8
mRatBN7.21410,712,489 - 10,737,153 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1410,712,489 - 10,737,153 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1410,681,236 - 10,705,924 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01411,981,060 - 12,005,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01410,676,050 - 10,700,766 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01412,362,912 - 12,387,572 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1412,359,363 - 12,387,102 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01412,306,370 - 12,331,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41412,065,635 - 12,090,295 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11412,065,634 - 12,090,295 (-)NCBI
Celera1410,801,184 - 10,825,826 (-)NCBICelera
Cytogenetic Map14p22NCBI
Bmp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554335,211,592 - 5,246,194 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554335,194,312 - 5,246,125 (+)NCBIChiLan1.0ChiLan1.0
BMP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1325,206,040 - 5,233,848 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl325,207,833 - 5,231,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3236,645,845 - 36,674,004 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0325,238,247 - 5,266,418 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl325,237,314 - 5,263,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1325,267,894 - 5,294,547 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0325,175,043 - 5,202,995 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03234,764,153 - 34,792,337 (-)NCBIUU_Cfam_GSD_1.0
Bmp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052857,106,302 - 7,130,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367491,025,546 - 1,053,902 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367491,025,867 - 1,053,578 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8136,880,456 - 136,904,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18136,880,456 - 136,904,739 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28146,174,734 - 146,199,020 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1729,454,394 - 29,482,560 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl729,455,761 - 29,482,896 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660377,954,672 - 7,982,356 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247579,956,293 - 9,980,234 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247579,952,847 - 9,980,259 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003832270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000057160   ⟹   ENSPPAP00000034279
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl448,992,266 - 49,019,205 (-)Ensembl
RefSeq Acc Id: XM_003832270   ⟹   XP_003832318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2349,012,023 - 49,039,117 (-)NCBI
NHGRI_mPanPan1449,200,736 - 49,227,920 (-)NCBI
Mhudiblu_PPA_v0443,143,784 - 43,170,854 (-)NCBI
PanPan1.1448,992,172 - 49,018,780 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003832318 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034279
  ENSPPAP00000034279.1
RefSeq Acc Id: XP_003832318   ⟸   XM_003832270
- UniProtKB: A0A2R9C6X0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000034279   ⟸   ENSPPAT00000057160
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039992 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057160.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro BMP3/BMP3B UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report pps:100978795 UniProtKB/TrEMBL
NCBI Gene BMP3 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 3 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
PIRSF BMP3/GDF10 UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A2R9C6X0 ENTREZGENE, UniProtKB/TrEMBL