STK24 (serine/threonine kinase 24) - Rat Genome Database

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Gene: STK24 (serine/threonine kinase 24) Pan paniscus
Analyze
Symbol: STK24
Name: serine/threonine kinase 24
RGD ID: 11792920
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of axon regeneration (ortholog); ASSOCIATED WITH Anal Atresia, Hypospadias, and Penoscrotal Inversion (ortholog); genetic disease (ortholog); holoprosencephaly (ortholog); FOUND IN Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase 24
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,971,360 - 100,101,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,638,326 - 98,770,286 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,614,662 - 79,744,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,764,900 - 98,834,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,764,900 - 98,837,807 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
Golgi membrane  (ISO)
nucleolus  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STK24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,971,360 - 100,101,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,638,326 - 98,770,286 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,614,662 - 79,744,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,764,900 - 98,834,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,764,900 - 98,837,807 (-)Ensemblpanpan1.1panPan2
STK24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381398,445,185 - 98,577,107 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1398,445,185 - 98,577,940 (-)EnsemblGRCh38hg38GRCh38
GRCh371399,097,439 - 99,229,361 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,900,456 - 98,027,397 (-)NCBINCBI36Build 36hg18NCBI36
Build 341397,902,414 - 97,972,253NCBI
Celera1379,949,846 - 80,077,659 (-)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,700,446 - 79,772,602 (-)NCBIHuRef
CHM1_11399,072,965 - 99,199,707 (-)NCBICHM1_1
T2T-CHM13v2.01397,652,976 - 97,785,805 (-)NCBIT2T-CHM13v2.0
Stk24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,521,599 - 121,618,269 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,523,755 - 121,617,423 (-)EnsemblGRCm39 Ensembl
GRCm3814121,284,187 - 121,380,496 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14121,286,343 - 121,380,011 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714121,685,563 - 121,778,452 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614120,421,978 - 120,514,242 (-)NCBIMGSCv36mm8
Celera14119,836,728 - 119,888,691 (-)NCBICelera
Cytogenetic Map14E5NCBI
cM Map1464.95NCBI
Stk24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,770,556 - 104,866,524 (-)NCBIGRCr8
mRatBN7.21598,363,707 - 98,458,940 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,365,791 - 98,460,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15102,299,497 - 102,392,528 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,401,180 - 103,493,619 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,328,792 - 100,421,293 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,629,258 - 106,678,917 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,629,312 - 106,678,918 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015110,023,434 - 110,073,159 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415106,256,862 - 106,307,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1597,151,107 - 97,200,834 (-)NCBICelera
Cytogenetic Map15q24NCBI
Stk24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540411,996,837 - 12,049,688 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540411,943,308 - 12,049,688 (+)NCBIChiLan1.0ChiLan1.0
STK24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,578,037 - 48,651,028 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,578,858 - 48,663,329 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2248,359,523 - 48,480,265 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02249,020,235 - 49,140,794 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2249,020,238 - 49,141,215 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,670,341 - 48,790,380 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,704,491 - 48,825,312 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,740,986 - 48,861,667 (-)NCBIUU_Cfam_GSD_1.0
Stk24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945184,063,450 - 184,118,436 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647211,833,646 - 11,888,705 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647211,788,439 - 11,888,703 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,458,351 - 67,634,349 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11167,458,350 - 67,565,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,695,345 - 74,782,296 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STK24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1377,104,417 - 77,231,402 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl377,105,429 - 77,196,934 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604633,585,578 - 33,717,376 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stk24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,474,373 - 12,595,062 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,474,346 - 12,595,052 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000014149   ⟹   ENSPPAP00000003053
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1398,764,900 - 98,834,505 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000014212   ⟹   ENSPPAP00000003069
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1398,765,907 - 98,837,807 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000014221   ⟹   ENSPPAP00000003073
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1398,765,907 - 98,836,871 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000014228   ⟹   ENSPPAP00000003080
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1398,765,907 - 98,834,498 (-)Ensembl
RefSeq Acc Id: XM_055096927   ⟹   XP_054952902
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21499,971,360 - 100,044,749 (-)NCBI
NHGRI_mPanPan11398,638,326 - 98,713,701 (-)NCBI
RefSeq Acc Id: XM_055096928   ⟹   XP_054952903
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21499,971,360 - 100,101,303 (-)NCBI
NHGRI_mPanPan11398,638,326 - 98,770,286 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054952902 (Get FASTA)   NCBI Sequence Viewer  
  XP_054952903 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003053.1
  ENSPPAP00000003069.1
  ENSPPAP00000003073.1
  ENSPPAP00000003080.1
RefSeq Acc Id: ENSPPAP00000003053   ⟸   ENSPPAT00000014149
RefSeq Acc Id: ENSPPAP00000003073   ⟸   ENSPPAT00000014221
RefSeq Acc Id: ENSPPAP00000003080   ⟸   ENSPPAT00000014228
RefSeq Acc Id: ENSPPAP00000003069   ⟸   ENSPPAT00000014212
RefSeq Acc Id: XP_054952903   ⟸   XM_055096928
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZDV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054952902   ⟸   XM_055096927
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZDX1 (UniProtKB/TrEMBL),   A0A2R8ZDV1 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000012674 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000014149.1 UniProtKB/TrEMBL
  ENSPPAT00000014212.1 UniProtKB/TrEMBL
  ENSPPAT00000014221.1 UniProtKB/TrEMBL
  ENSPPAT00000014228.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.12.70 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PDC10_dimerisation_sf UniProtKB/TrEMBL
  PDCD10_N UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
NCBI Gene STK24 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE 24 UniProtKB/TrEMBL
  STERILE20-LIKE KINASE, ISOFORM B-RELATED UniProtKB/TrEMBL
Pfam PDCD10_N UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R8ZDV1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZDX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZH52_PANPA UniProtKB/TrEMBL
  A0A2R8ZK29_PANPA UniProtKB/TrEMBL