SULT1E1 (sulfotransferase family 1E member 1)

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Gene: SULT1E1 (sulfotransferase family 1E member 1) Pan paniscus

Analyze

Symbol:

SULT1E1

Name:

sulfotransferase family 1E member 1

RGD ID:

11789078

Description:

ENCODES a protein that exhibits estrone sulfotransferase activity (ortholog); INVOLVED IN estrogen metabolic process (ortholog); female pregnancy (ortholog); sulfation (ortholog); PARTICIPATES IN estradiol biosynthetic pathway; paracetamol pharmacokinetics pathway; sulfite oxidase deficiency pathway; ASSOCIATED WITH alcoholic hepatitis (ortholog); breast cancer (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

estrogen sulfotransferase; sulfotransferase 1E1

RGD Orthologs

Human

Mouse

Rat

Dog

Pig

Green Monkey

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	60,714,305 - 60,733,229 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	60,713,392 - 60,733,229 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	54,377,681 - 54,396,619 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alcoholic hepatitis (ISO)

breast cancer (ISO)

Chemical and Drug Induced Liver Injury (ISO)

endometrial cancer (ISO)

Experimental Liver Cirrhosis (ISO)

Kabuki Syndrome 1 (ISO)

liver disease (ISO)

Neoplasm Metastasis (ISO)

Prostatic Neoplasms (ISO)

Reperfusion Injury (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-phosphoadenosine 5'-phosphosulfate metabolic process (IEA)

estrogen catabolic process (IEA)

estrogen metabolic process (IEA,ISO)

ethanol catabolic process (IEA)

female pregnancy (ISO)

positive regulation of fat cell differentiation (IEA)

sulfation (IEA,ISO)

Cellular Component

cytoplasm (ISO)

cytosol (IEA)

nuclear membrane (IEA)

Molecular Function

estrone sulfotransferase activity (ISO)

flavonol 3-sulfotransferase activity (IEA)

protein binding (ISO)

steroid sulfotransferase activity (IEA)

sulfotransferase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

estradiol biosynthetic pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

sulfite oxidase deficiency pathway (ISO)

References

Genomics

Comparative Map Data

SULT1E1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	60,714,305 - 60,733,229 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	60,713,392 - 60,733,229 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	54,377,681 - 54,396,619 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SULT1E1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	69,821,122 - 69,860,145 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	4	69,841,212 - 69,860,145 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	70,706,930 - 70,725,863 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	70,741,519 - 70,760,459 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	70,887,690 - 70,906,630	NCBI
Celera	4	68,060,253 - 68,079,193 (-)	NCBI		Celera
Cytogenetic Map	4	q13.3	NCBI
HuRef	4	66,504,780 - 66,523,720 (-)	NCBI		HuRef
CHM1_1	4	70,743,366 - 70,762,280 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	73,176,039 - 73,194,973 (-)	NCBI		T2T-CHM13v2.0

Sult1e1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	87,723,827 - 87,739,470 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	87,723,828 - 87,739,453 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	87,575,968 - 87,591,611 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	87,575,969 - 87,591,594 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	88,004,993 - 88,020,636 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	88,650,530 - 88,666,155 (-)	NCBI		MGSCv36	mm8
Celera	5	84,792,542 - 84,808,207 (-)	NCBI		Celera
Cytogenetic Map	5	E1	NCBI
cM Map	5	43.56	NCBI

Sult1e1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	20,422,324 - 20,439,562 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	20,422,324 - 20,439,275 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	20,610,541 - 20,627,768 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	14	21,929,454 - 21,946,681 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	14	20,684,867 - 20,702,117 (+)	NCBI	Rnor_WKY
Rnor_6.0	14	22,070,861 - 22,089,264 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	22,072,024 - 22,089,248 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	21,985,847 - 22,004,150 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	14	19,831,652 - 19,842,299 (+)	NCBI		Celera
Cytogenetic Map	14	p21	NCBI

LOC482182
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	59,323,430 - 59,343,745 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	59,052,730 - 59,072,999 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	60,119,719 - 60,140,008 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	60,120,936 - 60,140,217 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	59,734,248 - 59,754,528 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	59,195,062 - 59,214,797 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	60,339,614 - 60,359,890 (-)	NCBI		UU_Cfam_GSD_1.0

SULT1E1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	66,811,550 - 66,834,473 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	66,811,536 - 66,838,181 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SULT1E1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	18,313,510 - 18,330,768 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	18,313,238 - 18,330,741 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666084	4,599,800 - 4,616,560 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003809013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000030548 ⟹ ENSPPAP00000007927

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	4	60,713,392 - 60,732,448 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000030553 ⟹ ENSPPAP00000007931

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	4	60,713,392 - 60,732,448 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000030556 ⟹ ENSPPAP00000007934

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	4	60,714,281 - 60,733,229 (+)	Ensembl

RefSeq Acc Id:

XM_003809013 ⟹ XP_003809061

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1	4	60,714,305 - 60,733,229 (+)	NCBI
Mhudiblu_PPA_v0	4	54,377,681 - 54,396,619 (+)	NCBI

Sequence:

show sequence

CAAATGCAGAAGTGGTTCTCATCTTTTTTTGCAGCTTAAGATCTGCCTTGGTATTTGAAGAGAT
CTAAACTAGATCAATTTCTTTCACAGGATCAACTAAACAGTGTACCACAATGAATTCTGAACTT
GACTATTATGAAAAGTTTGAAGAAGTCCATGGGATTCTAATGTATAAAGATTTTGTCAAATATT
GGGATAATGTGGAAGCGTTCCAGGCAAGACCAGATGATCTTGTAATTGCCACCTACCCTAAATC
TGGTACAACCTGGGTTAGTGAAATTGTGTATATGATCTATAAAGAGGGTGATGTGGAAAAGTGC
AAAGAAGATGTAATTTTTAATCGAATACCTTTCCTGGAATGCAGAAAAGAAAACCTCATGAATG
GAGTAAAACAATTAGATGAGATGAATTCTCCTAGAATTGTGAAGACTCATTTGCCACCTGAACT
TCTTCCTGCCTCATTTTGGGAAAAGAATTGTAAGATAATCTATCTTTGCCGGAATGCAAAGGAT
GTGGCTGTTTCCTTTTATTATTTCTTTCTAATGGTGGCTGGTCATCCAAATCCTGGATCCTTTC
CAGAGTTTGTGGAGAAATTCATGCAAGGACAGGTTCCTTATGGTTCCTGGTATAAACATGTAAA
ATCTTGGTGGGAAAAGGGAAAGAGTCCACGTGTACTATTTCTTTTCTATGAAGACCTCAAAGAG
GATATCAGAAAAGAGGTGATAAAATTGATACATTTCCTGGAGAGGAAGCCATCAGAGGAGCTTG
TGGACAGGATTATACATCATACTTCATTCCAAGAGATGAAGAACAATCCATCCACAAATTACAC
AACACTGCCAGATGAAATTATGAACCAGAAATTGTCGCCCTTCATGAGAAAGGGAATTACAGGA
GACTGGAAAAATCACTTTACAGTAGCCCTGAATGAAAAATTTGATAAACATTATGAGCAGCAAA
TGAAGGAATCTACACTGAAGTTTCGAACTGAGATCTAAGAAGGTCTTTCTTTACTTAACATATC
TGATATTAAAGATTTCTTTTCATCATTCTCCACTTTTTCTTATTTTAGATTGCTAGAAAAGACA
TAATCATGGATTATGTTGACATTTTCTTTTTAAATTTTTGTTTAACATTTTTTTTTTTTTTTTG
AGACAGAGTCTCACTCTGTTGCCTAGGCTGGAGGACAGTGGCACAATCATGGCTGATTGCAGCC
TTGACCTCCTTGACTCAATTGATCCTCCCATCTCAGCCTCCCAAGTAGCTAGGACTACAGACAT
GTGAAACCATGCTTGGCTAATTTTTTTAATGTTTTTTTGTAGAGATGAGGTCTTATTATATTTT
CCAGGCTGGTCTTGAATTCCTGGGCTCAAGCTTCCCAAGTAGCTGCAACAACAGGCACACACCA
CCATGCTCAACTAATTTTATTTCTATTTTTTGTATAGACAGGGGCTTGCTATAGGGTCCAGGCT
GGTCTGAAACCCTTGAGCTCAAGTGATCTTCCCACACCAGCCTCCCAAAATACTGGGATTACAG
GCTTGAGCCTCCATGCCTGGCCCAGGCAACATGTTTATTGAGCTGTACATACATATGAGAAATA
AGAAACTTTTTTTCCTACTATCATCTCTTAAATTTTGTTTTCTTTTTCTTTTGCTTCCTCTTCT
TCTTTTCTATTTTTTATAAATATCATGCACAACTATAACCTATGGGAATGATGTAGTAACACAG
ATTATTCATCTTGTTAGAGTTGTATTAAAAATAAACAAGCATTTCAAATTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003809061	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_003809061 ⟸ XM_003809013

- UniProtKB:

A0A2J8PF39 (UniProtKB/TrEMBL), A0A2R8ZSI9 (UniProtKB/TrEMBL), A0A6D2X4G2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNSELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEG
DVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKNCKIIYLC
RNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFY
EDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMR
KGITGDWKNHFTVALNEKFDKHYEQQMKESTLKFRTEI

hide sequence

RefSeq Acc Id:

ENSPPAP00000007931 ⟸ ENSPPAT00000030553

RefSeq Acc Id:

ENSPPAP00000007927 ⟸ ENSPPAT00000030548

RefSeq Acc Id:

ENSPPAP00000007934 ⟸ ENSPPAT00000030556

Protein Domains

Sulfotransfer_1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000027190	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000007927.1	UniProtKB/TrEMBL
	ENSPPAP00000007931.1	UniProtKB/TrEMBL
	ENSPPAP00000007934	ENTREZGENE
	ENSPPAP00000007934.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000030548.1	UniProtKB/TrEMBL
	ENSPPAT00000030553.1	UniProtKB/TrEMBL
	ENSPPAT00000030556.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Sulfotransferase_dom	UniProtKB/TrEMBL
KEGG Report	pps:100972770	UniProtKB/TrEMBL
NCBI Gene	SULT1E1	ENTREZGENE
Pfam	Sulfotransfer_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A2J8PF39	ENTREZGENE
	A0A2R8ZSI9	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZVR2_PANPA	UniProtKB/TrEMBL
	A0A6D2X4G2	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

RGD Manual Annotations

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