PITX2 (paired like homeodomain 2)

Gene: PITX2 (paired like homeodomain 2) Pan paniscus

Analyze

Symbol:

PITX2

Name:

paired like homeodomain 2

RGD ID:

11781493

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN anatomical structure morphogenesis (ortholog); animal organ morphogenesis (ortholog); atrial cardiac muscle tissue morphogenesis (ortholog); ASSOCIATED WITH anterior segment dysgenesis (ortholog); anterior segment dysgenesis 1 (ortholog); anterior segment dysgenesis 4 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

pituitary homeobox 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	108,707,912 - 108,728,100 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	109,000,309 - 109,020,681 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	103,112,624 - 103,137,356 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	113,676,846 - 113,696,518 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

anterior segment dysgenesis (ISO)

anterior segment dysgenesis 1 (ISO)

anterior segment dysgenesis 4 (ISO)

anterior segment dysgenesis 5 (ISO)

Arts syndrome (ISO)

atrial fibrillation (ISO)

autosomal dominant polycystic kidney disease (ISO)

Axenfeld-Rieger syndrome (ISO)

Axenfeld-Rieger syndrome type 1 (ISO)

cataract (ISO)

cleft palate (ISO)

congenital heart disease (ISO)

Craniofacial Abnormalities (ISO)

De Hauwere syndrome (ISO)

Familial Atrial Fibrillation 1 (ISO)

genetic disease (ISO)

glaucoma (ISO)

heart septal defect (ISO)

hypothyroidism (ISO)

iridogoniodysgenesis syndrome (ISO)

lung adenocarcinoma (ISO)

Peters anomaly (ISO)

Pituitary Stalk Interruption Syndrome (ISO)

prostate cancer (ISO)

ring dermoid of cornea (ISO)

Stroke (ISO)

Tooth Abnormalities (ISO)

Wolff-Parkinson-White syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IEA,ISO)

animal organ morphogenesis (IEA,ISO)

atrial cardiac muscle tissue morphogenesis (ISO)

atrioventricular valve development (ISO)

branching involved in blood vessel morphogenesis (ISO)

camera-type eye development (ISO)

cardiac muscle cell differentiation (ISO)

cardiac muscle tissue development (ISO)

cardiac neural crest cell migration involved in outflow tract morphogenesis (ISO)

cell proliferation involved in outflow tract morphogenesis (ISO)

deltoid tuberosity development (ISO)

determination of left/right symmetry (ISO)

digestive system development (ISO)

embryonic camera-type eye development (ISO)

embryonic digestive tract morphogenesis (ISO)

embryonic heart tube left/right pattern formation (ISO)

embryonic hindlimb morphogenesis (ISO)

endodermal digestive tract morphogenesis (ISO)

extraocular skeletal muscle development (ISO)

female gonad development (ISO)

heart development (ISO)

hypothalamus cell migration (ISO)

in utero embryonic development (ISO)

iris morphogenesis (ISO)

left lung morphogenesis (ISO)

left/right axis specification (ISO)

lung development (ISO)

male gonad development (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

neuron differentiation (ISO)

neuron migration (ISO)

odontogenesis (ISO)

odontogenesis of dentin-containing tooth (ISO)

outflow tract morphogenesis (ISO)

pituitary gland development (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

pulmonary myocardium development (ISO)

pulmonary vein morphogenesis (ISO)

regulation of cell migration (ISO)

regulation of cell population proliferation (ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IEA,ISO)

response to hormone (ISO)

response to vitamin A (ISO)

skeletal muscle tissue development (ISO)

spleen development (ISO)

subthalamic nucleus development (ISO)

superior vena cava morphogenesis (ISO)

system development (IEA)

vascular associated smooth muscle cell differentiation (ISO)

vasculogenesis (ISO)

ventricular cardiac muscle cell development (ISO)

ventricular septum morphogenesis (ISO)

Wnt signaling pathway (ISO)

Cellular Component

cytoplasm (ISO)

nucleoplasm (ISO)

nucleus (IEA)

transcription regulator complex (ISO)

Molecular Function

chromatin binding (ISO)

chromatin DNA binding (ISO)

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor binding (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

identical protein binding (ISO)

phosphoprotein binding (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

ribonucleoprotein complex binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA,ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

transcription cis-regulatory region binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PITX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	108,707,912 - 108,728,100 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	109,000,309 - 109,020,681 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	103,112,624 - 103,137,356 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	113,676,846 - 113,696,518 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

PITX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	110,617,423 - 110,642,123 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	110,617,423 - 110,642,123 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	111,538,579 - 111,563,279 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	111,758,028 - 111,777,957 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	111,896,185 - 111,916,112	NCBI
Celera	4	108,832,403 - 108,852,329 (-)	NCBI		Celera
Cytogenetic Map	4	q25	NCBI
HuRef	4	107,270,120 - 107,294,817 (-)	NCBI		HuRef
CHM1_1	4	111,515,486 - 111,540,182 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	113,919,284 - 113,943,981 (-)	NCBI		T2T-CHM13v2.0

Pitx2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	128,993,527 - 129,013,243 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	128,993,527 - 129,013,240 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	129,199,878 - 129,219,594 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	129,199,878 - 129,219,591 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	128,902,836 - 128,922,509 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	129,191,965 - 129,211,613 (+)	NCBI		MGSCv36	mm8
Celera	3	135,706,515 - 135,726,130 (+)	NCBI		Celera
Cytogenetic Map	3	G3	NCBI
cM Map	3	57.84	NCBI

Pitx2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	220,391,417 - 220,411,588 (+)	NCBI		GRCr8
mRatBN7.2	2	217,717,738 - 217,737,293 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	217,717,693 - 217,737,293 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	225,392,106 - 225,411,651 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	223,291,763 - 223,311,312 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	218,149,443 - 218,168,994 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	233,602,732 - 233,621,059 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	233,602,732 - 233,621,129 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	252,929,195 - 252,948,179 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	226,581,170 - 226,601,319 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	226,567,811 - 226,587,999 (+)	NCBI
Celera	2	210,013,296 - 210,033,592 (+)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

Pitx2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	15,803,219 - 15,823,310 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955457	15,803,493 - 15,823,193 (+)	NCBI	ChiLan1.0	ChiLan1.0

PITX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	30,710,161 - 30,730,162 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	30,710,685 - 30,730,273 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	11,306,508 - 11,326,539 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	30,931,178 - 30,951,191 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	30,931,702 - 30,947,061 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	30,916,988 - 30,937,021 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	30,667,533 - 30,687,592 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	9,167,168 - 9,187,192 (+)	NCBI		UU_Cfam_GSD_1.0

Pitx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	10,214,001 - 10,237,701 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936563	1,713,294 - 1,732,431 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PITX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	111,698,757 - 111,723,298 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	111,697,364 - 111,723,295 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	119,906,708 - 119,926,114 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PITX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	58,501,669 - 58,526,413 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	58,501,559 - 58,507,318 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	37,182,289 - 37,203,030 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pitx2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624838	4,871,511 - 4,886,384 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624838	4,872,279 - 4,889,780 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003830027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003830029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024928711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057302133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_003830027 ⟹ XP_003830075

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	108,707,912 - 108,713,718 (-)	NCBI
NHGRI_mPanPan1	4	109,000,309 - 109,006,816 (-)	NCBI
Mhudiblu_PPA_v0	4	103,112,624 - 103,118,428 (-)	NCBI
PanPan1.1	4	113,676,846 - 113,682,525 (-)	NCBI

Sequence:

show sequence

GTTAGGCCAACAGGGAAGCGCGGAGCCGCAGATCTGGTCCGTCGCTCGCCTGGGTGCCTGGAGC
TGAGCTGCGGCAAGGCCCGGCTCCTGTTCGACCGCCCGAGGGGTGTGCGTGTGCGCGTTGCGGA
GGGTGCGCTCAGAGGGCCGCGTCGTTGCTGCAGCGGCTGCTGCCGCCGCAGGGGATCTAATATC
AGCTACCTGTCCCTGTCACTCTTGACACTTCTCTGTCAGGGCTGCCGCGTTGGGGGGCGGGCAG
AGCGCGGTCGGCGTTAGCTTTCCTTATTGGAGGGGTTCTTGGGGGAGGGAGGGAGAGAAGAAGG
GGGTCTTTGCCCACTCTTGTTTCGCTTTGGAGCTTGGAAGCCTGCTCCCTAAAGACGCTCCGAG
TGGTGCCCTTCTGCCCACATCCCATGTCTTCGTTTGCCCGCTGACTTTCCGTCTCCGGACTTTT
TCGCTTGAGCCTTCCGGAGGAGACGGGGGCAGCTTGGCTTGAGAACTCGGCGGGGGTTGCGTCC
CCTGGCTCTCCCCACAGCGGGGAAACTCCGCGCCTAGAGCGCGACCCGGAGCGGGCAGCGGCGG
CTACGGGGGCTCGGCGGGGCAGTAGCCGAGGACTAGTAGAGCGTCGCGCTCCCTCGTCCATGAA
CTGCATGAAAGGCCCGCTTCACTTGGAGCACCGAGCAGCGGGGACCAAGCTGTCGGCCGTCTCC
TCATCTTCCTGTCACCATCCCCAGCCATTAGCCATGGCTTCGGTTCTGGCTCCCGGTCAGCCCC
GCTCCCTGGACTCCTCCAAGCACAGGCTGGAGGTGCACACCATCTCCGACACCTCCAGCCCGGA
GGCCGCAGAGAAAGATAAAAGCCAGCAGGGGAAGAATGAGGACGTGGGCGCCGAGGACCCGTCT
AAGAAGAAGCGGCAAAGGCGGCAGCGGACTCACTTTACCAGCCAGCAGCTCCAGGAGCTGGAGG
CCACTTTCCAGAGGAACCGCTACCCGGACATGTCCACACGCGAAGAAATCGCTGTGTGGACCAA
CCTTACGGAAGCCCGAGTCCGGGTTTGGTTCAAGAATCGTCGGGCCAAATGGAGAAAGAGGGAG
CGCAACCAGCAGGCCGAGCTATGCAAGAATGGCTTCGGGCCGCAGTTCAATGGGCTCATGCAGC
CCTACGACGACATGTACCCAGGCTATTCCTACAACAACTGGGCCGCCAAGGGCCTTACATCCGC
CTCCCTATCCACCAAGAGCTTCCCCTTCTTCAACTCTATGAACGTCAACCCCCTGTCATCACAG
AGCATGTTTTCCCCACCCAACTCTATCTCGTCCATGAGCATGTCGTCCAGCATGGTGCCCTCAG
CAGTGACGGGCGTCCCGGGCTCCAGTCTCAACAGCCTGAATAACTTGAACAACCTGAGTAGCCC
GTCGCTGAATTCCGCGGTGCCGACGCCTGCCTGTCCTTACGCGCCGCCGACTCCTCCGTATGTT
TATAGGGACACGTGTAACTCGAGCCTGGCCAGCCTGAGACTGAAAGCAAAGCAGCACTCCAGCT
TCGGCTACGCCAGCGTGCAGAACCCGGCCTCCAACCTGAGTGCTTGCCAGTATGCAGTGGACCG
GCCCGTGTGAGCCGCACCCACAGCGCCGGGATCCTAGGACCTTGCCGGATGGGGCAACTCCGCC
CTTGAAAGACTGGGAATTATGCTAGAAGGTCGTGGGCACTAAAGAAAGGGAGAGAAAGAGAAGC
TATATAGAGAAAAGGAAACCACTGAATCAAAGAGAGAGCTCCTTTGATTTCAAAGGGATGTCCT
CAGTGTCTGACATCTTTCACTACAAGTATTTCCAACAGTTGCAAGGACACATACACAAACAAAT
GTTTGACTGGATATGACATTTTAACATTACTATAAGCTTGTTATTTTTTAAGTTTAGCATTGTT
AACATTTAAATGACTGAAAGGATGTATATATATCGAAATGTCAAATTAATTTTATAAAAGCAGT
TGTTAGTAATATCACAACAGTGTTTTTAAAGGTTAGGCTTTAAAATAAAGCATGTTATACAGAA
GCGATTAGGATTTTTCGCTTGCGAGCAAGGGAGTGTATATACTAAATGCCACACTGTATGTTTC
TAACATATTATTATTATTATAAAAAATGTGTGAATATCAGTTTTAGAATAGTTTCTCTGGTGGA
TGCAATGATGTTTCTGAAACTGCTATGTACAACCTACCCTGTGTATAACATTTCGTACAATATT
ATTGTTTTACTTTTCAGCAAATATGAAAAAAATGTGTTTTATTTCATGGGAGTAAAATATACTG
CATACAAA

hide sequence

RefSeq Acc Id:

XM_034959003 ⟹ XP_034814894

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	108,707,912 - 108,728,100 (-)	NCBI
NHGRI_mPanPan1	4	109,000,309 - 109,020,681 (-)	NCBI
Mhudiblu_PPA_v0	4	103,112,624 - 103,137,356 (-)	NCBI

RefSeq Acc Id:

XM_057302133 ⟹ XP_057158116

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	108,707,912 - 108,727,996 (-)	NCBI
NHGRI_mPanPan1	4	109,000,309 - 109,020,681 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003830075	(Get FASTA)	NCBI Sequence Viewer
	XP_034814894	(Get FASTA)	NCBI Sequence Viewer
	XP_057158116	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000036111.1
	ENSPPAP00000036117.1
	ENSPPAP00000036121.1
	ENSPPAP00000036127
	ENSPPAP00000036127.1

RefSeq Acc Id:	XP_003830075 ⟸ XM_003830027
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9CCR8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSS PEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW TNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLT SASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLS SPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAV DRPV hide sequence

RefSeq Acc Id:	XP_034814894 ⟸ XM_034959003
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CCQ9 (UniProtKB/TrEMBL), A0A2R9C2G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_057158116 ⟸ XM_057302133
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9C2F5 (UniProtKB/TrEMBL)

Protein Domains

Homeobox OAR

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040833	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000059002.1	UniProtKB/TrEMBL
	ENSPPAT00000059008.1	UniProtKB/TrEMBL
	ENSPPAT00000059012.1	UniProtKB/TrEMBL
	ENSPPAT00000059018.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
	Homeobox_Pitx/unc30	UniProtKB/TrEMBL
	OAR_dom	UniProtKB/TrEMBL
KEGG Report	pps:100977891	UniProtKB/TrEMBL
NCBI Gene	PITX2	ENTREZGENE
PANTHER	PITUITARY HOMEOBOX 2	UniProtKB/TrEMBL
	PITUITARY HOMEOBOX HOMOLOG PTX1	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
	OAR	UniProtKB/TrEMBL
PIRSF	Homeobox_protein_Pitx/Unc30	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	OAR	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A2R9C2F5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C2G4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CCQ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CCR8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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