TBCA (tubulin folding cofactor A) - Rat Genome Database

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Gene: TBCA (tubulin folding cofactor A) Pan paniscus
Analyze
Symbol: TBCA
Name: tubulin folding cofactor A
RGD ID: 11780557
Description: ENCODES a protein that exhibits beta-tubulin binding (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); protein folding (inferred); tubulin complex assembly (inferred); ASSOCIATED WITH genetic disease (ortholog); Hermansky-Pudlak syndrome 2 (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin-specific chaperone A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2437,527,521 - 37,611,910 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1535,681,134 - 35,765,561 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0537,530,924 - 37,615,330 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1538,060,299 - 38,144,457 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl538,060,398 - 38,144,457 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TBCA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2437,527,521 - 37,611,910 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1535,681,134 - 35,765,561 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0537,530,924 - 37,615,330 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1538,060,299 - 38,144,457 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl538,060,398 - 38,144,457 (+)Ensemblpanpan1.1panPan2
TBCA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38577,691,166 - 77,776,339 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl577,691,166 - 77,868,780 (-)EnsemblGRCh38hg38GRCh38
GRCh37576,986,991 - 77,072,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36577,022,751 - 77,107,941 (-)NCBINCBI36Build 36hg18NCBI36
Build 34577,022,828 - 77,107,886NCBI
Celera572,881,651 - 72,966,197 (-)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef572,194,090 - 72,279,072 (-)NCBIHuRef
CHM1_1576,421,166 - 76,506,343 (-)NCBICHM1_1
T2T-CHM13v2.0578,173,750 - 78,258,323 (-)NCBIT2T-CHM13v2.0
Tbca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391394,925,428 - 94,979,431 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1394,925,418 - 94,979,430 (+)EnsemblGRCm39 Ensembl
GRCm381394,788,920 - 94,842,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1394,788,910 - 94,842,922 (+)EnsemblGRCm38mm10GRCm38
MGSCv371395,558,898 - 95,612,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361395,889,642 - 95,943,598 (+)NCBIMGSCv36mm8
Celera1398,402,227 - 98,458,103 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1349.22NCBI
Tbca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8227,745,985 - 27,800,624 (+)NCBIGRCr8
mRatBN7.2226,011,714 - 26,065,909 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,011,795 - 26,065,907 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx233,040,787 - 33,094,941 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0231,141,021 - 31,195,175 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0225,964,928 - 26,019,082 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0224,449,498 - 24,505,351 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl224,449,485 - 24,505,334 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0243,661,385 - 43,671,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera222,083,636 - 22,136,709 (+)NCBICelera
Cytogenetic Map2q12NCBI
Tbca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542523,300,480 - 23,313,497 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542523,301,457 - 23,312,740 (+)NCBIChiLan1.0ChiLan1.0
TBCA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1328,972,469 - 29,027,436 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl328,910,025 - 29,025,297 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha330,189,342 - 30,265,020 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0328,873,151 - 28,948,560 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl328,873,170 - 28,954,090 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1328,807,711 - 28,882,941 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0328,785,816 - 28,861,651 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0329,116,567 - 29,192,256 (+)NCBIUU_Cfam_GSD_1.0
Tbca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213185,112,177 - 185,176,324 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365495,682,630 - 5,746,777 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365495,682,558 - 5,746,784 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBCA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl286,579,835 - 86,665,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1286,581,603 - 86,664,994 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2288,189,131 - 88,273,262 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBCA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1471,921,187 - 72,004,619 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604920,759,981 - 20,843,497 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248692,153,570 - 2,228,543 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248692,153,427 - 2,228,166 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003812640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000050741   ⟹   ENSPPAP00000027898
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl538,060,398 - 38,144,261 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050744   ⟹   ENSPPAP00000027901
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl538,060,398 - 38,144,261 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050745   ⟹   ENSPPAP00000027902
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl538,127,378 - 38,144,457 (+)Ensembl
RefSeq Acc Id: XM_003812640   ⟹   XP_003812688
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2437,527,521 - 37,611,910 (+)NCBI
NHGRI_mPanPan1535,681,134 - 35,765,561 (+)NCBI
Mhudiblu_PPA_v0537,530,924 - 37,615,330 (+)NCBI
PanPan1.1538,060,299 - 38,144,457 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003812688 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027898
  ENSPPAP00000027898.1
  ENSPPAP00000027901.1
  ENSPPAP00000027902.1
Reference Protein Sequences
RefSeq Acc Id: XP_003812688   ⟸   XM_003812640
- UniProtKB: A0A2R9BFC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000027901   ⟸   ENSPPAT00000050744
RefSeq Acc Id: ENSPPAP00000027898   ⟸   ENSPPAT00000050741
RefSeq Acc Id: ENSPPAP00000027902   ⟸   ENSPPAT00000050745


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037014 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050741.1 UniProtKB/TrEMBL
  ENSPPAT00000050744.1 UniProtKB/TrEMBL
  ENSPPAT00000050745.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.90 UniProtKB/TrEMBL
InterPro TBCA UniProtKB/TrEMBL
  TBCA_sf UniProtKB/TrEMBL
NCBI Gene TBCA ENTREZGENE
PANTHER PTHR21500 UniProtKB/TrEMBL
  TUBULIN-SPECIFIC CHAPERONE A UniProtKB/TrEMBL
  TUBULIN-SPECIFIC CHAPERONE A UniProtKB/TrEMBL
Pfam TBCA UniProtKB/TrEMBL
Superfamily-SCOP SSF46988 UniProtKB/TrEMBL
UniProt A0A2R9BFC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BHZ7_PANPA UniProtKB/TrEMBL
  A0A2R9BMK7_PANPA UniProtKB/TrEMBL