KLHL24 (kelch like family member 24) - Rat Genome Database

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Gene: KLHL24 (kelch like family member 24) Pan paniscus
Analyze
Symbol: KLHL24
Name: kelch like family member 24
RGD ID: 11780025
Description: INVOLVED IN intermediate filament organization (inferred); protein autoubiquitination (inferred); protein ubiquitination (inferred); ASSOCIATED WITH 3-Methylcrotonyl-CoA carboxylase 1 deficiency (ortholog); congenital disorder of glycosylation Id (ortholog); Currarino syndrome (ortholog); FOUND IN adherens junction (inferred); Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch-like 24; kelch-like protein 24
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,505,763 - 181,569,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,510,545 - 181,574,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03180,669,767 - 180,731,186 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13188,837,980 - 188,888,933 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,839,457 - 188,885,385 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
KLHL24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,505,763 - 181,569,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,510,545 - 181,574,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03180,669,767 - 180,731,186 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13188,837,980 - 188,888,933 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,839,457 - 188,885,385 (+)Ensemblpanpan1.1panPan2
KLHL24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383183,635,623 - 183,684,519 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3183,635,610 - 183,684,519 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,353,411 - 183,402,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363184,836,105 - 184,885,001 (+)NCBINCBI36Build 36hg18NCBI36
Celera3181,794,950 - 181,843,839 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3180,759,268 - 180,810,190 (+)NCBIHuRef
CHM1_13183,317,525 - 183,366,726 (+)NCBICHM1_1
T2T-CHM13v2.03186,445,098 - 186,493,998 (+)NCBIT2T-CHM13v2.0
Klhl24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391619,916,286 - 19,947,976 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1619,916,292 - 19,947,971 (+)EnsemblGRCm39 Ensembl
GRCm381620,097,553 - 20,129,226 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,097,542 - 20,129,221 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,097,627 - 20,127,817 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,011,097 - 20,041,287 (+)NCBIMGSCv36mm8
Celera1620,661,389 - 20,691,296 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.36NCBI
Klhl24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,348,024 - 94,382,085 (-)NCBIGRCr8
mRatBN7.21180,843,621 - 80,877,649 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,566,617 - 89,597,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,219,965 - 82,250,790 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,281,103 - 81,311,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,613,101 - 84,643,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,675,249 - 87,705,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,094,560 - 83,126,617 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11183,152,149 - 83,184,206 (-)NCBI
Celera1179,681,696 - 79,711,857 (-)NCBICelera
Cytogenetic Map11q23NCBI
Klhl24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,700,035 - 23,735,301 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,700,030 - 23,733,021 (-)NCBIChiLan1.0ChiLan1.0
KLHL24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13416,583,683 - 16,625,778 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3416,590,368 - 16,621,041 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3420,671,915 - 20,713,790 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03416,491,764 - 16,533,422 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3416,491,815 - 16,533,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13416,530,507 - 16,572,150 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03416,517,530 - 16,559,186 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03416,755,202 - 16,797,365 (+)NCBIUU_Cfam_GSD_1.0
Klhl24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602120,024,263 - 120,061,122 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365786,116,068 - 6,151,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365786,116,117 - 6,151,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13121,570,591 - 121,608,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113121,564,833 - 121,608,146 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,001,698 - 131,061,043 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,732,347 - 5,780,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,732,928 - 5,780,143 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606314,515,358 - 14,565,756 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,807,780 - 72,844,190 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473072,803,070 - 72,843,627 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008957366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034957794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063602626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000045084   ⟹   ENSPPAP00000022276
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3188,839,457 - 188,885,385 (+)Ensembl
RefSeq Acc Id: XM_008957366   ⟹   XP_008955614
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,830 - 181,556,767 (+)NCBI
NHGRI_mPanPan13181,510,545 - 181,561,441 (+)NCBI
Mhudiblu_PPA_v03180,669,767 - 180,720,673 (+)NCBI
PanPan1.13188,837,982 - 188,888,933 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957368   ⟹   XP_008955616
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,825 - 181,556,767 (+)NCBI
NHGRI_mPanPan13181,510,563 - 181,561,441 (+)NCBI
Mhudiblu_PPA_v03180,669,776 - 180,720,673 (+)NCBI
PanPan1.13188,837,980 - 188,888,933 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034957787   ⟹   XP_034813678
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
NHGRI_mPanPan13181,510,550 - 181,561,441 (+)NCBI
Mhudiblu_PPA_v03180,669,767 - 180,720,673 (+)NCBI
RefSeq Acc Id: XM_034957788   ⟹   XP_034813679
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
NHGRI_mPanPan13181,510,550 - 181,561,441 (+)NCBI
Mhudiblu_PPA_v03180,669,772 - 180,720,673 (+)NCBI
RefSeq Acc Id: XM_034957790   ⟹   XP_034813681
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
NHGRI_mPanPan13181,510,550 - 181,561,441 (+)NCBI
Mhudiblu_PPA_v03180,669,767 - 180,720,673 (+)NCBI
RefSeq Acc Id: XM_034957792   ⟹   XP_034813683
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,551,298 (+)NCBI
NHGRI_mPanPan13181,518,415 - 181,556,017 (+)NCBI
Mhudiblu_PPA_v03180,677,630 - 180,714,042 (+)NCBI
RefSeq Acc Id: XM_034957794   ⟹   XP_034813685
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,569,697 (+)NCBI
NHGRI_mPanPan13181,518,415 - 181,574,403 (+)NCBI
Mhudiblu_PPA_v03180,677,630 - 180,731,186 (+)NCBI
RefSeq Acc Id: XM_063602617   ⟹   XP_063458687
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,763 - 181,556,767 (+)NCBI
RefSeq Acc Id: XM_063602618   ⟹   XP_063458688
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,863 - 181,556,767 (+)NCBI
RefSeq Acc Id: XM_063602619   ⟹   XP_063458689
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
RefSeq Acc Id: XM_063602620   ⟹   XP_063458690
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
RefSeq Acc Id: XM_063602621   ⟹   XP_063458691
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,551,298 (+)NCBI
RefSeq Acc Id: XM_063602622   ⟹   XP_063458692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,834 - 181,551,298 (+)NCBI
RefSeq Acc Id: XM_063602623   ⟹   XP_063458693
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,856 - 181,551,298 (+)NCBI
RefSeq Acc Id: XM_063602624   ⟹   XP_063458694
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,569,697 (+)NCBI
RefSeq Acc Id: XM_063602625   ⟹   XP_063458695
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,834 - 181,569,697 (+)NCBI
RefSeq Acc Id: XM_063602626   ⟹   XP_063458696
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,505,835 - 181,556,767 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008955614   ⟸   XM_008957366
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B4A0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008955616   ⟸   XM_008957368
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B4A0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034813678   ⟸   XM_034957787
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B4A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034813681   ⟸   XM_034957790
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B4A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034813679   ⟸   XM_034957788
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B4A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034813685   ⟸   XM_034957794
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034813683   ⟸   XM_034957792
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000022276   ⟸   ENSPPAT00000045084
RefSeq Acc Id: XP_063458687   ⟸   XM_063602617
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458695   ⟸   XM_063602625
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063458692   ⟸   XM_063602622
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063458694   ⟸   XM_063602624
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063458696   ⟸   XM_063602626
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063458689   ⟸   XM_063602619
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458690   ⟸   XM_063602620
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063458691   ⟸   XM_063602621
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063458693   ⟸   XM_063602623
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063458688   ⟸   XM_063602618
- Peptide Label: isoform X1
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034331 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045084.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  KLHL24 UniProtKB/TrEMBL
  KLHL24_BACK UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report pps:100980858 UniProtKB/TrEMBL
NCBI Gene KLHL24 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  PTHR24412:SF215 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A2R9B4A0 ENTREZGENE, UniProtKB/TrEMBL