SEPTIN2 (septin 2) - Rat Genome Database
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Gene: SEPTIN2 (septin 2) Pan paniscus
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Symbol: SEPTIN2
Name: septin 2
RGD ID: 11776807
Description: ENCODES a protein that exhibits enzyme regulator activity (ortholog); identical protein binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cilium assembly (ortholog); neuron projection development (ortholog); regulation of L-glutamate import across plasma membrane (ortholog); ASSOCIATED WITH methylmalonic acidemia (ortholog); FOUND IN actin cytoskeleton (ortholog); axoneme (ortholog); cell projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: SEPT2; septin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B247,380,771 - 247,419,556 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,380,771 - 247,419,556 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B128,586,659 - 128,624,991 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
SEPTIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B247,380,771 - 247,419,556 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,380,771 - 247,419,556 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B128,586,659 - 128,624,991 (+)NCBIMhudiblu_PPA_v0panPan3
SEPTIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,315,100 - 241,354,027 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,315,270 - 241,354,027 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,254,723 - 242,293,442 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,903,396 - 241,942,115 (+)NCBINCBI36hg18NCBI36
Build 342241,974,712 - 242,013,429NCBI
Celera2235,924,022 - 235,962,784 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2234,010,626 - 234,049,134 (+)NCBIHuRef
CHM1_12242,260,686 - 242,299,397 (+)NCBICHM1_1
Septin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,406,671 - 93,437,455 (+)NCBIGRCm39mm39
GRCm38193,478,981 - 93,509,733 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,478,964 - 93,510,260 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl193,478,993 - 93,509,733 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,375,570 - 95,406,310 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,309,450 - 95,340,136 (+)NCBImm8
Celera196,424,640 - 96,455,361 (+)NCBICelera
Cytogenetic Map1DNCBI
Septin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.09100,624,876 - 100,658,053 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,624,876 - 100,658,050 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09100,277,885 - 100,311,082 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,756,091 - 92,789,257 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1992,960,859 - 92,994,023 (+)NCBI
Celera991,552,840 - 91,585,967 (+)NCBICelera
Cytogenetic Map9q36NCBI
Septin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955542401,081 - 444,304 (-)NCBIChiLan1.0ChiLan1.0
SEPTIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2551,296,554 - 51,328,616 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12551,296,486 - 51,330,508 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Septin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936745518,650 - 555,187 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15140,023,822 - 140,058,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115140,023,836 - 140,058,291 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215154,711,203 - 154,738,280 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110127,378,393 - 127,421,012 (+)NCBI
ChlSab1.1 Ensembl10127,387,280 - 127,421,201 (+)Ensembl
Septin2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248475,341,177 - 5,382,920 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044923   ⟹   ENSPPAP00000022116
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,380,771 - 247,419,556 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044939   ⟹   ENSPPAP00000022132
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,382,132 - 247,415,702 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044961   ⟹   ENSPPAP00000022154
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,389,872 - 247,415,702 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044987   ⟹   ENSPPAP00000022180
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,389,872 - 247,415,702 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044992   ⟹   ENSPPAP00000022185
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,389,872 - 247,415,702 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044998   ⟹   ENSPPAP00000022191
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,400,022 - 247,415,702 (+)Ensembl
RefSeq Acc Id: XM_003813067   ⟹   XP_003813115
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12B247,381,531 - 247,419,556 (+)NCBI
Mhudiblu_PPA_v02B128,587,308 - 128,624,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003813068   ⟹   XP_003813116
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12B247,380,771 - 247,419,556 (+)NCBI
Mhudiblu_PPA_v02B128,586,659 - 128,624,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955565   ⟹   XP_034811456
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B128,587,308 - 128,624,991 (+)NCBI
RefSeq Acc Id: XM_034955566   ⟹   XP_034811457
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B128,587,312 - 128,624,991 (+)NCBI
RefSeq Acc Id: XM_034955567   ⟹   XP_034811458
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B128,587,302 - 128,624,991 (+)NCBI
RefSeq Acc Id: XM_034955568   ⟹   XP_034811459
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B128,587,312 - 128,624,991 (+)NCBI
RefSeq Acc Id: XM_034955569   ⟹   XP_034811460
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B128,587,334 - 128,624,991 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_003813116   ⟸   XM_003813068
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003813115   ⟸   XM_003813067
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034811458   ⟸   XM_034955567
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034811456   ⟸   XM_034955565
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034811459   ⟸   XM_034955568
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034811457   ⟸   XM_034955566
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034811460   ⟸   XM_034955569
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000022116   ⟸   ENSPPAT00000044923
RefSeq Acc Id: ENSPPAP00000022132   ⟸   ENSPPAT00000044939
RefSeq Acc Id: ENSPPAP00000022154   ⟸   ENSPPAT00000044961
RefSeq Acc Id: ENSPPAP00000022180   ⟸   ENSPPAT00000044987
RefSeq Acc Id: ENSPPAP00000022191   ⟸   ENSPPAT00000044998
RefSeq Acc Id: ENSPPAP00000022185   ⟸   ENSPPAT00000044992
Protein Domains
Septin-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034127 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022116 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000022132 UniProtKB/TrEMBL
  ENSPPAP00000022154 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000022180 UniProtKB/TrEMBL
  ENSPPAP00000022185 UniProtKB/TrEMBL
  ENSPPAP00000022191 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044923 UniProtKB/TrEMBL
  ENSPPAT00000044939 UniProtKB/TrEMBL
  ENSPPAT00000044961 UniProtKB/TrEMBL
  ENSPPAT00000044987 UniProtKB/TrEMBL
  ENSPPAT00000044992 UniProtKB/TrEMBL
  ENSPPAT00000044998 UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
  Septin2 UniProtKB/TrEMBL
KEGG Report pps:100989789 UniProtKB/TrEMBL
NCBI Gene SEPT2 ENTREZGENE
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PRINTS SEPTIN2 UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AXW5_PANPA UniProtKB/TrEMBL
  A0A2R9AY75_PANPA UniProtKB/TrEMBL
  A0A2R9AY80_PANPA UniProtKB/TrEMBL
  A0A2R9B1V4_PANPA UniProtKB/TrEMBL
  A0A2R9B3R7_PANPA UniProtKB/TrEMBL
  A0A2R9B3Y9_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-09 SEPTIN2  septin 2  SEPT2    Symbol and/or name change 5135510 APPROVED