COPS8 (COP9 signalosome subunit 8) - Rat Genome Database

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Gene: COPS8 (COP9 signalosome subunit 8) Pan paniscus
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Symbol: COPS8
Name: COP9 signalosome subunit 8
RGD ID: 11776506
Description: INVOLVED IN activation of NF-kappaB-inducing kinase activity (ortholog); negative regulation of cell population proliferation (ortholog); protein deneddylation (ortholog); ASSOCIATED WITH Bethlem Myopathy 1 (ortholog); intellectual disability (ortholog); FOUND IN COP9 signalosome (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: COP9 constitutive photomorphogenic homolog subunit 8; COP9 signalosome complex subunit 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B243,168,836 - 243,182,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B243,169,322 - 243,182,937 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B124,315,423 - 124,328,830 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
COPS8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B243,168,836 - 243,182,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B243,169,322 - 243,182,937 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B124,315,423 - 124,328,830 (+)NCBIMhudiblu_PPA_v0panPan3
COPS8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2237,085,882 - 237,100,474 (+)EnsemblGRCh38hg38GRCh38
GRCh382237,085,889 - 237,100,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372237,994,532 - 238,009,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,658,823 - 237,672,228 (+)NCBINCBI36hg18NCBI36
Celera2231,707,494 - 231,720,899 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2229,786,783 - 229,800,188 (+)NCBIHuRef
CHM1_12238,000,165 - 238,013,570 (+)NCBICHM1_1
Cops8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39190,531,147 - 90,541,063 (+)NCBIGRCm39mm39
GRCm39 Ensembl190,530,703 - 90,541,063 (+)Ensembl
GRCm38190,602,960 - 90,613,341 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl190,602,981 - 90,613,341 (+)EnsemblGRCm38mm10GRCm38
MGSCv37192,500,000 - 92,509,916 (+)NCBIGRCm37mm9NCBIm37
MGSCv36192,433,385 - 92,443,499 (+)NCBImm8
Celera193,547,395 - 93,557,311 (+)NCBICelera
Cytogenetic Map1DNCBI
Cops8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2991,207,427 - 91,217,258 (+)NCBI
Rnor_6.0 Ensembl997,772,184 - 97,782,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0997,772,224 - 97,782,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0997,453,705 - 97,463,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4989,802,461 - 89,812,293 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1990,007,229 - 90,017,062 (+)NCBI
Celera988,751,960 - 88,761,790 (+)NCBICelera
Cytogenetic Map9q36NCBI
Cops8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555423,128,194 - 3,140,232 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555423,129,184 - 3,140,232 (-)NCBIChiLan1.0ChiLan1.0
COPS8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12547,783,241 - 47,796,806 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2548,282,068 - 48,295,660 (+)NCBI
ROS_Cfam_1.02548,132,414 - 48,146,025 (+)NCBI
UMICH_Zoey_3.12548,045,560 - 48,059,155 (+)NCBI
UNSW_CanFamBas_1.02547,833,252 - 47,846,852 (+)NCBI
UU_Cfam_GSD_1.02548,065,106 - 48,078,718 (+)NCBI
Cops8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303189,759,148 - 189,770,708 (+)NCBI
SpeTri2.0NW_0049365251,168,995 - 1,180,763 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPS8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,827,862 - 136,838,048 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,828,222 - 136,838,058 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215151,269,694 - 151,279,487 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COPS8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110123,075,589 - 123,089,209 (+)NCBI
Cops8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248472,609,760 - 2,620,804 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000032992   ⟹   ENSPPAP00000010342
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B243,169,322 - 243,182,937 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000033002   ⟹   ENSPPAP00000010352
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B243,170,182 - 243,181,961 (+)Ensembl
RefSeq Acc Id: XM_003813109   ⟹   XP_003813157
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12B243,168,836 - 243,182,937 (+)NCBI
Mhudiblu_PPA_v02B124,315,423 - 124,328,830 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955425   ⟹   XP_034811316
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02B124,315,551 - 124,328,820 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003813157 (Get FASTA)   NCBI Sequence Viewer  
  XP_034811316 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003813157   ⟸   XM_003813109
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034811316   ⟸   XM_034955425
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000010342   ⟸   ENSPPAT00000032992
RefSeq Acc Id: ENSPPAP00000010352   ⟸   ENSPPAT00000033002
Protein Domains
CSN8_PSD8_EIF3K   PCI


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000010342 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000010352 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032992 UniProtKB/TrEMBL
  ENSPPAT00000033002 UniProtKB/TrEMBL
InterPro COP9_CSN8 UniProtKB/TrEMBL
  CSN8_PSD8_EIF3K UniProtKB/TrEMBL
  PCI_dom UniProtKB/TrEMBL
KEGG Report pps:100979569 UniProtKB/TrEMBL
NCBI Gene COPS8 ENTREZGENE
PANTHER PTHR13339 UniProtKB/TrEMBL
Pfam CSN8_PSD8_EIF3K UniProtKB/TrEMBL
PROSITE PCI UniProtKB/TrEMBL
UniProt A0A2R8ZZD4_PANPA UniProtKB/TrEMBL
  A0A2R8ZZE6_PANPA UniProtKB/TrEMBL