NMNAT3 (nicotinamide nucleotide adenylyltransferase 3) - Rat Genome Database

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Gene: NMNAT3 (nicotinamide nucleotide adenylyltransferase 3) Pan paniscus
Analyze
Symbol: NMNAT3
Name: nicotinamide nucleotide adenylyltransferase 3
RGD ID: 11774784
Description: ENCODES a protein that exhibits catalytic activity (inferred); nicotinamide-nucleotide adenylyltransferase activity (inferred); nicotinate-nucleotide adenylyltransferase activity (inferred); INVOLVED IN NAD biosynthetic process (ortholog); response to tumor necrosis factor (ortholog); response to wounding (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH glaucoma (ortholog); polycystic ovary syndrome (ortholog); FOUND IN axon (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DTW domain-containing protein 1 pseudogene; LOC103782968; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,472,086 - 137,592,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,476,826 - 137,597,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,594,825 - 136,715,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,196,529 - 144,313,658 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NMNAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,472,086 - 137,592,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,476,826 - 137,597,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,594,825 - 136,715,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,196,529 - 144,313,658 (-)NCBIpanpan1.1PanPan1.1panPan2
NMNAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,560,180 - 139,678,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,560,180 - 139,678,017 (-)EnsemblGRCh38hg38GRCh38
GRCh373139,279,022 - 139,396,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,761,723 - 140,879,530 (-)NCBINCBI36Build 36hg18NCBI36
Build 343140,761,731 - 140,879,538NCBI
Celera3137,701,933 - 137,819,739 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,654,467 - 136,772,328 (-)NCBIHuRef
CHM1_13139,242,474 - 139,360,320 (-)NCBICHM1_1
T2T-CHM13v2.03142,307,606 - 142,425,486 (-)NCBIT2T-CHM13v2.0
Nmnat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,169,487 - 98,302,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,169,488 - 98,302,491 (+)EnsemblGRCm39 Ensembl
GRCm38998,287,433 - 98,420,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,287,435 - 98,420,438 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,197,002 - 98,311,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,105,935 - 98,220,780 (+)NCBIMGSCv36mm8
Celera997,850,409 - 97,963,936 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.35NCBI
Nmnat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,771,124 - 107,888,528 (+)NCBIGRCr8
mRatBN7.2898,892,168 - 99,003,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl898,873,398 - 99,020,645 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,561,145 - 104,672,788 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,760,392 - 102,872,044 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,602,906 - 100,714,552 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,317,038 - 106,429,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,760,369 - 105,871,374 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,472,426 - 103,584,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18103,491,880 - 103,603,693 (+)NCBI
Celera898,304,722 - 98,415,332 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nmnat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555085,913,898 - 6,022,128 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555085,909,808 - 6,024,301 (+)NCBIChiLan1.0ChiLan1.0
NMNAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,714,162 - 35,829,150 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,714,933 - 35,829,049 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,701,815 - 35,816,030 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02336,250,931 - 36,365,957 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,250,934 - 36,366,221 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,933,008 - 36,047,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02336,006,480 - 36,121,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,249,065 - 36,363,588 (-)NCBIUU_Cfam_GSD_1.0
Nmnat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,886,743 - 75,026,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,636,380 - 1,766,306 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,653,243 - 1,766,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,429,639 - 80,556,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21388,294,211 - 88,321,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11550,880,146 - 50,990,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1550,880,235 - 50,991,281 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604123,853,934 - 23,964,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmnat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473016,158,485 - 16,231,670 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473016,151,185 - 16,289,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_008951940   ⟹   XP_008950188
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,090 - 137,592,641 (-)NCBI
NHGRI_mPanPan13137,476,829 - 137,597,360 (-)NCBI
Mhudiblu_PPA_v03136,596,895 - 136,715,369 (-)NCBI
PanPan1.13144,196,529 - 144,313,658 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951941   ⟹   XP_008950189
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,089 - 137,592,677 (-)NCBI
NHGRI_mPanPan13137,476,829 - 137,597,364 (-)NCBI
Mhudiblu_PPA_v03136,596,895 - 136,715,370 (-)NCBI
PanPan1.13144,196,529 - 144,313,658 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024928348   ⟹   XP_024784116
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,086 - 137,592,699 (-)NCBI
NHGRI_mPanPan13137,476,826 - 137,597,422 (-)NCBI
Mhudiblu_PPA_v03136,596,895 - 136,715,426 (-)NCBI
PanPan1.13144,196,529 - 144,313,658 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034957508   ⟹   XP_034813399
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,088 - 137,592,701 (-)NCBI
NHGRI_mPanPan13137,476,827 - 137,597,424 (-)NCBI
Mhudiblu_PPA_v03136,597,954 - 136,715,432 (-)NCBI
RefSeq Acc Id: XM_034957509   ⟹   XP_034813400
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,087 - 137,592,705 (-)NCBI
NHGRI_mPanPan13137,476,827 - 137,597,430 (-)NCBI
Mhudiblu_PPA_v03136,594,826 - 136,715,437 (-)NCBI
RefSeq Acc Id: XM_034957510   ⟹   XP_034813401
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,087 - 137,592,681 (-)NCBI
NHGRI_mPanPan13137,476,827 - 137,597,365 (-)NCBI
Mhudiblu_PPA_v03136,594,826 - 136,715,370 (-)NCBI
RefSeq Acc Id: XM_055110537   ⟹   XP_054966512
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,089 - 137,592,679 (-)NCBI
NHGRI_mPanPan13137,476,828 - 137,597,365 (-)NCBI
RefSeq Acc Id: XM_055110538   ⟹   XP_054966513
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,485,378 - 137,592,701 (-)NCBI
NHGRI_mPanPan13137,490,108 - 137,597,425 (-)NCBI
RefSeq Acc Id: XM_055110539   ⟹   XP_054966514
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,087 - 137,592,706 (-)NCBI
NHGRI_mPanPan13137,476,827 - 137,597,430 (-)NCBI
RefSeq Acc Id: XM_055110540   ⟹   XP_054966515
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,090 - 137,592,687 (-)NCBI
NHGRI_mPanPan13137,476,829 - 137,597,368 (-)NCBI
RefSeq Acc Id: XM_055110541   ⟹   XP_054966516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,472,089 - 137,592,694 (-)NCBI
NHGRI_mPanPan13137,476,828 - 137,597,413 (-)NCBI
RefSeq Acc Id: XP_008950189   ⟸   XM_008951941
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008950188   ⟸   XM_008951940
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024784116   ⟸   XM_024928348
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_034813400   ⟸   XM_034957509
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034813401   ⟸   XM_034957510
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034813399   ⟸   XM_034957508
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054966514   ⟸   XM_055110539
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054966516   ⟸   XM_055110541
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BK86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966512   ⟸   XM_055110537
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054966515   ⟸   XM_055110540
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BK86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966513   ⟸   XM_055110538
- Peptide Label: isoform X3
Protein Domains
Cytidyltransferase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038038 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052932.1 UniProtKB/TrEMBL
Gene3D-CATH HUPs UniProtKB/TrEMBL
InterPro Cyt_trans-like UniProtKB/TrEMBL
  Euk_NMN_adenylyltrnsfrase UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
NCBI Gene NMNAT3 ENTREZGENE
PANTHER NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE UniProtKB/TrEMBL
  NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 UniProtKB/TrEMBL
Pfam CTP_transf_like UniProtKB/TrEMBL
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
UniProt A0A2R9BK86 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 NMNAT3  nicotinamide nucleotide adenylyltransferase 3  LOC103782968  DTW domain-containing protein 1 pseudogene  Data merged from RGD:11855391 737654 PROVISIONAL