TMEM87A (transmembrane protein 87A)

Gene: TMEM87A (transmembrane protein 87A) Pan paniscus

Analyze

Symbol:

TMEM87A

Name:

transmembrane protein 87A

RGD ID:

11771446

Description:

ENCODES a protein that exhibits mechanosensitive potassium channel activity (ortholog); INVOLVED IN detection of mechanical stimulus involved in sensory perception of touch (ortholog); retrograde transport, endosome to Golgi (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog); ruffle (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	31,454,478 - 31,516,978 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	35,607,661 - 35,670,158 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	21,164,958 - 21,227,644 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	39,325,405 - 39,386,297 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	39,325,412 - 39,386,297 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to mechanical stimulus (IEA)

detection of mechanical stimulus involved in sensory perception of touch (ISO)

retrograde transport, endosome to Golgi (IEA,ISO)

Cellular Component

cytosol (IEA)

Golgi apparatus (IEA)

Golgi cisterna membrane (IEA)

membrane (IEA)

plasma membrane (ISO)

ruffle (ISO)

Molecular Function

mechanosensitive potassium channel activity (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

TMEM87A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	31,454,478 - 31,516,978 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	35,607,661 - 35,670,158 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	21,164,958 - 21,227,644 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	39,325,405 - 39,386,297 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	39,325,412 - 39,386,297 (-)	Ensembl	panpan1.1		panPan2

TMEM87A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	42,210,447 - 42,273,584 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	42,210,447 - 42,273,534 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	42,502,645 - 42,565,782 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	40,290,026 - 40,352,923 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	19,270,425 - 19,333,454 (-)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	19,350,875 - 19,413,910 (-)	NCBI		HuRef
CHM1_1	15	42,621,193 - 42,684,241 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	40,016,476 - 40,079,617 (-)	NCBI		T2T-CHM13v2.0

Tmem87a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	120,185,790 - 120,234,597 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	120,185,793 - 120,234,594 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	120,355,309 - 120,404,154 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	120,355,312 - 120,404,113 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	120,181,045 - 120,229,852 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	120,046,753 - 120,095,530 (-)	NCBI		MGSCv36	mm8
Celera	2	121,509,631 - 121,558,612 (-)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.31	NCBI

Tmem87a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	127,761,490 - 127,807,314 (-)	NCBI		GRCr8
mRatBN7.2	3	107,307,726 - 107,353,571 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,307,726 - 107,353,551 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	112,128,138 - 112,174,097 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	112,132,351 - 112,174,269 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,675,873 - 118,721,830 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	106,845,250 - 106,892,596 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	106,750,517 - 106,789,043 (-)	NCBI
Celera	3	106,216,021 - 106,261,761 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

Tmem87a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	8,937,110 - 8,990,800 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	8,938,758 - 8,990,800 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM87A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	9,215,585 - 9,253,712 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	9,216,702 - 9,253,700 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	9,273,738 - 9,311,932 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	9,350,326 - 9,388,853 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	9,350,330 - 9,388,833 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	9,270,636 - 9,308,807 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	9,375,705 - 9,414,213 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	9,509,957 - 9,548,150 (-)	NCBI		UU_Cfam_GSD_1.0

Tmem87a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	87,669,313 - 87,730,113 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	5,516,332 - 5,578,290 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	5,517,362 - 5,578,290 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM87A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	129,098,388 - 129,142,161 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	129,098,388 - 129,142,168 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	143,990,773 - 144,034,547 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM87A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	40,722,283 - 40,785,001 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	40,722,464 - 40,785,863 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	100,218,419 - 100,281,098 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem87a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624804	9,340,382 - 9,400,739 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624804	9,339,274 - 9,400,887 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003805608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008973226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008973229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024925667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034938584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055098322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055098323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000044962 ⟹ ENSPPAP00000022155

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	39,325,412 - 39,386,297 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000044964 ⟹ ENSPPAP00000022157

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	39,326,581 - 39,385,989 (-)	Ensembl

RefSeq Acc Id:

XM_008973229 ⟹ XP_008971477

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	31,494,873 - 31,516,978 (-)	NCBI
NHGRI_mPanPan1	15	35,641,248 - 35,670,158 (-)	NCBI
Mhudiblu_PPA_v0	15	21,212,328 - 21,227,644 (-)	NCBI
PanPan1.1	15	39,370,995 - 39,386,297 (-)	NCBI

Sequence:

show sequence

AGTAGGTCCAAAGTCTCACGGCGCACAGACGACTGTCTGAGAGAGACGCCGCTACGCCGCACAG
CAAACAAGCCCCGCGACGTTTCCAGGACCCGGATAATCCCGCCCTTAGAGCAGAGCCGGAAGAA
GGCGGGACGAACCGGAAAAGGGTGAAATGCTTTCGGTAGGCACTCCACGGCTGTGAAGATGGCG
GCGGCTGCGTGGCTTCAGGTGTTGCCTGTCATTCTTCTGCTTCTGGGAGCTCACCCGTCACCAC
TGTCGTTTTTCAGTGCGGGACCGGCAACCGTAGCTGCTGCTGACCGGTCCAAATGGCACATTCC
GATACCGTCGGGGAAAAATTATTTTAGTTTTGGAAAGATCCTCTTCAGAAATACCACTATCTTC
CTGAAGTTTGATGGAGAACCTTGTGACCTGTCTTTGAATATAACCTGGTATCTGAAAAGCGCTG
ATTGTTACAATGAAATCTATAACTTCAAGGCAGAAGAAGTAGAGTTGTATTTGGAAAAACTTAA
GGAAAAAAGAGGCTTGTCTGGGAAATATCAAACATCATCAAAATTGTTCCAGAACTGCAGTGAA
CTCTTTAAAACACAGAGCTTTTCTGGAGATTTTATGCATCGACTGCCTCTTTTAGGAGAAAAAC
AGGAGGCTAAGGAGAATGGAACAAACCTTACCTTTATTGGAGACAAAACCATTCAGATGCCTTT
CTTGAAGAAACATTTCTTGGATTGTTGAAAGACTTTAATAATTTCCAAAGTTCCAAAAGTTGAT
TTTGATAGTTTTTGCCAGTGTTTTCGTTGCTTTTATGGATGAGTAGATTTTCAGAGCTTCTTAT
TCTGCCATTCTGAAAGTGTTCTCACTACCTAAACCCTAGTTTTATTTGTACAGAATTTTAACTG
AATGTAAGTTAGGCATGACAGTCTTTGTTAATTTTTTAAACAAAAGATAGCCATTAGGACTGGG
TGCAGTGGCTCACACCTGTAATGCCAACACTTTGGGAGGCCAAGGTAGGCAGATGACTTGAGGT
TGGGAGTTCGAGACCAGCTTGGCCAATGTGGTGAAACTTTGTCTTTACTAAAAATACAAAAATT
AGTTGCTCATGGTGGCGGGCACCTGTAATCCAAGCTACTCAGGAGGCTGAGGCAGGAGAATTGC
GTGAACTTGGGAGGTGGAGGCTGCAGTGAGCTGAGATCACGCTACTGCACTCCGGCCTGGGCAA
CCAGTGAGATTCCACCTCAAAAAAAAAGAAAAAAGATATTCATTGGATTTTCTCTTACTAATAG
GTATATATTCACTATGAAAATGGAGACGATATACATAAATGAAGAAAATAGTAATCTATAATAC
CATGCAGTGATATATTTATCTTCCTAGTCTTTTGTATATGGGCATGTTTATATTATTTTAAAAA
GGGAATCTTAGAGTATGTATTGTATGACTTTTTTTTGTAGCTTAGCAATATAACATGGACATGT
CGTCAGTTTGGTAAATATTGTATTGCATTGTTACTTAAATGCTTGTATAGTGTCTTATTGTATG
AGTACATTGCAATTTGTTCAATTATCTGTTCTTGAACATTTATGAGTTTCATTATCTTGGAATT
TTATGCAGTGTTGTGATTAATATTTTAACTACATTTGCTTTTAAGTCTTTATTTTCTGATCTCA
GAAGAATTGTATATTGGGATAAGTTTTTATTTCTATAACTTAAAAGTAACAATCCTTTGTAATT
TTATGTTC

hide sequence

RefSeq Acc Id:

XM_055098322 ⟹ XP_054954297

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	31,454,478 - 31,516,978 (-)	NCBI
NHGRI_mPanPan1	15	35,607,661 - 35,670,158 (-)	NCBI

RefSeq Acc Id:

XM_055098323 ⟹ XP_054954298

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	31,454,478 - 31,516,978 (-)	NCBI
NHGRI_mPanPan1	15	35,607,661 - 35,670,158 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008971477	(Get FASTA)	NCBI Sequence Viewer
	XP_054954297	(Get FASTA)	NCBI Sequence Viewer
	XP_054954298	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022155.1
	ENSPPAP00000022157.1

RefSeq Acc Id:	XP_008971477 ⟸ XM_008973229
- Peptide Label:	isoform X3
- Sequence:	show sequence MAAAAWLQVLPVILLLLGAHPSPLSFFSAGPATVAAADRSKWHIPIPSGKNYFSFGKILFRNTT IFLKFDGEPCDLSLNITWYLKSADCYNEIYNFKAEEVELYLEKLKEKRGLSGKYQTSSKLFQNC SELFKTQSFSGDFMHRLPLLGEKQEAKENGTNLTFIGDKTIQMPFLKKHFLDC hide sequence

RefSeq Acc Id:

ENSPPAP00000022157 ⟸ ENSPPAT00000044964

RefSeq Acc Id:

ENSPPAP00000022155 ⟸ ENSPPAT00000044962

RefSeq Acc Id:	XP_054954298 ⟸ XM_055098323
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054954297 ⟸ XM_055098322
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AY46 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034270	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000044962.1	UniProtKB/TrEMBL
	ENSPPAT00000044964.1	UniProtKB/TrEMBL
InterPro	GPR107/GPR108-like	UniProtKB/TrEMBL
KEGG Report	pps:100985462	UniProtKB/TrEMBL
NCBI Gene	TMEM87A	ENTREZGENE
PANTHER	PTHR21229	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 87A	UniProtKB/TrEMBL
Pfam	Lung_7-TM_R	UniProtKB/TrEMBL
UniProt	A0A2R9AY46	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B1X5_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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