ZNF8 (zinc finger protein 8) - Rat Genome Database

Name: ZNF8
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: ZNF8 (zinc finger protein 8) Pan paniscus

Analyze

Symbol:

ZNF8

Name:

zinc finger protein 8

RGD ID:

11771273

Description:

ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN BMP signaling pathway (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC106634154; uncharacterized LOC106634154

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF8 (zinc finger protein 8)	NCBI	Ortholog
Mus musculus (house mouse):	Zfp128 (zinc finger protein 128)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	LOC108348304 (zinc finger protein 8-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf8 (zinc finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	64,556,103 - 64,592,743 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	66,343,578 - 66,380,638 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	55,288,349 - 55,324,982 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	64,113,775 - 64,131,500 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	64,113,776 - 64,130,917 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

BMP signaling pathway (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

ZNF8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	64,556,103 - 64,592,743 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	66,343,578 - 66,380,638 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	55,288,349 - 55,324,982 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	64,113,775 - 64,131,500 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	64,113,776 - 64,130,917 (+)	Ensembl	panpan1.1		panPan2

ZNF8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	58,278,955 - 58,302,791 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	58,278,955 - 58,302,791 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	58,790,321 - 58,814,157 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	63,482,130 - 63,499,066 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	63,482,129 - 63,499,066	NCBI
Celera	19	55,834,184 - 55,851,131 (+)	NCBI		Celera
Cytogenetic Map	19	q13.43	NCBI
HuRef	19	55,099,455 - 55,116,321 (+)	NCBI		HuRef
CHM1_1	19	58,784,502 - 58,801,442 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	61,375,360 - 61,399,206 (+)	NCBI		T2T-CHM13v2.0

Zfp128
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	12,615,105 - 12,627,349 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	12,615,104 - 12,627,349 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	12,881,178 - 12,893,422 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	12,881,177 - 12,893,422 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	13,466,527 - 13,478,771 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	11,781,386 - 11,793,601 (+)	NCBI		MGSCv36	mm8
Celera	7	10,506,489 - 10,518,729 (+)	NCBI		Celera
Cytogenetic Map	7	A1	NCBI
cM Map	7	7.67	NCBI

LOC108348304
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Celera	1	60,327,446 - 60,340,311 (-)	NCBI		Celera
Cytogenetic Map	1		NCBI

Znf8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955584	993,104 - 998,612 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955584	992,927 - 1,004,645 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZNF8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	99,644,778 - 99,654,993 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	99,642,446 - 99,655,014 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	100,037,475 - 100,050,023 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	100,283,167 - 100,295,935 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	100,283,177 - 100,295,926 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	99,928,619 - 99,941,165 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	99,641,224 - 99,653,777 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	100,396,133 - 100,408,682 (-)	NCBI		UU_Cfam_GSD_1.0

Znf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	218,232,606 - 218,250,241 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004937350	30,531 - 48,347 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	62,894,704 - 62,905,838 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	62,894,617 - 62,914,448 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	57,592,971 - 57,632,370 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	50,565,414 - 50,579,192 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	50,565,540 - 50,578,862 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	3,863,680 - 3,877,893 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	241,437 - 252,743 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	235,610 - 252,356 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003816637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001337520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004667974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000035787 ⟹ ENSPPAP00000013119

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	64,113,776 - 64,130,917 (+)	Ensembl

RefSeq Acc Id:

XM_003816637 ⟹ XP_003816685

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	64,556,103 - 64,592,743 (+)	NCBI
NHGRI_mPanPan1	19	66,343,578 - 66,380,638 (+)	NCBI
Mhudiblu_PPA_v0	19	55,288,349 - 55,305,308 (+)	NCBI
PanPan1.1	19	64,113,776 - 64,130,917 (+)	NCBI

Sequence:

show sequence

AGTTGTAGTCGCCGCGTCGCCGGTGCGGCCGCCATTGTCCGGCGTTCGGCGAGTCGGGTGGTCC
CTTTGGCTGGAGTGCCTCTCTGGTCTGGGGATCACCTCAGGCGCTATCCTTCACTGGGCGATCC
AGCATGGACCCCGAGGACGAAGGGGTAGCGGGAGTGATGTCTGTGGGGCCGCCGGCGGCCCGGC
TTCAGGAACCAGTGACCTTCCGGGATGTGGCTGTGGACTTTACCCAGGAGGAATGGGGGCAGCT
GGACCCTACCCAGAGGATCCTCTACCGTGACGTGATGCTGGAGACCTTTGGTCACCTGCTCTCC
ATAGGTCCTGAGCTTCCGAAGCCTGAAGTCATCTCCCAGCTGGAGCAAGGGACCGAGCTATGGG
TGGCTGAGAGAGGAACCACCCAGGGCTGCCATCCAGGCTGGGAGCCTCGATCTGAAAGCCAAGC
ATCACGCAAGGAAGAGGGCCTGCCTGAAGAGGAGCCATCCCATGTCACGGGAAGGGAAGGATTC
CCGACAGATGCTCCTTATCCCACCACGTTAGGGAAAGACAGGGAGTGTCAGAGCCAGAGTCTGG
CACTCAAGGAGCAGAATAACTTGAAGCAGTTGGAATTTGGCCTCAAGGAAGCACCAGTTCAAGA
TCAAGGCTACAAAACTCTCAGACTCGGGGAAAACTGCGTCCTGAGTTCAAGCCCAAATCCATTC
CCAGAGATCTCTAGAGGGGAGTATTTGTATACTTACAACTCACAGATTACAGACTCAGAACATA
ACTCCAGCTTAGTCAGTCAGCAGACAGGCTCCCCAGGAAAACAGCCCGGTGAAAACAGTGACTG
TCACAGAGATTCCAGTCAGGCCATTCCAATTATGGAACTCACAAAAAGCCAGGTGCAGGACAAA
CCCTACAAATGTACTGACTGTGGGAAGTCATTTAACCATAACGCACACCTCACCGTGCACAAGA
GGATTCATACGGGAGAAAGACCTTATATGTGCAAGGAGTGTGGGAAAGCCTTCAGCCAGAACTC
CTCCCTCGTCCAGCACGAGCGCATCCACACTGGAGACAAGCCCTACAAGTGTGCCGAATGTGGG
AAGTCTTTCTGCCATAGTACACACCTTACCGTCCATCGGAGGATTCACACTGGGGAGAAGCCCT
ACGAGTGTCAGGACTGTGGGAGGGCCTTCAACCAGAACTCCTCCCTGGGGCGGCACAAGAGGAC
ACACACTGGGGAGAAGCCATACACCTGCAGTGTGTGTGGGAAATCCTTCTCTCGGACCACTTGC
CTTTTCCTGCACCTGAGAACTCACACCGAGGAGAGGCCCTACGAGTGTAACCACTGCGGGAAGG
GCTTCAGGCACAGCTCATCCCTGGCCCAGCACCAGCGGAAGCACGCGGGGGAGAAGCCCTTTGA
GTGCCGCCAGAGGCTGATCTTTGAGCAGACGCCAGCTCTCACAAAGCATGAATGGACAGAAGCC
CTGGGCTGTGACCCACCTTTGAGTCAAGATGAGAGGACTCACCGAAGTGACAGACCCTTCAAAT
GTAATCAGTGTGGGAAGTGTTTCATTCAGAGCTCTCACCTCATCCGGCACCAGATAACTCACAC
CAGAGAGGAGCAGCCCCATGGGCGAAGCCGGCGGCGTGAACAATCCTCGAGCAGGAACTCACAC
CTGGTTCAGCATCAACACTCGAACTCCAGAAAGAGCTCTGCAGGCGGAGCAAAGGCAGGGCAGC
CGGAAAGCAGAGCCCTGGCTTTGTTTGACATCCAAAAAATCATGCAAGAGAAAAACCCTGTGCA
CGTTATTGGGGTGGAAGAGCCTTCTGTGGGTGCTTCCATGTTATTTGACATCAGAGAATCCACA
TAGGAGAGAAACTTTGCTGATGACTTTTAACCACAAGTAAAAAATGTGGTAAGTCCACATAGTG
TACTCATGGAAAGAGGGGCTGGGGGTAGAAATGTCATGGGTGACTTGTGACTTTCTAAGGAAAT
GATGCTTCCCAAGCACCCGAGGTTGGTTGGTCCCAAATCTATCAAACTCAGTGCCCTCTTTAGC
GACATATTTTGTGACATTCCTTCCATTACACCACAGTGAGTTCACAGGTAATATAACCTACCCA
CCTGTGTAATGTCAAAAAAAATCAATATGCAGCCCCATTTTGTAAAGGATCATTAAAATGAAAG
TAATTTATGGTAGAGTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003816685	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000013119
	ENSPPAP00000013119.1

RefSeq Acc Id:

XP_003816685 ⟸ XM_003816637

- UniProtKB:

A0A2R9A750 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPEDEGVAGVMSVGPPAARLQEPVTFRDVAVDFTQEEWGQLDPTQRILYRDVMLETFGHLLSI
GPELPKPEVISQLEQGTELWVAERGTTQGCHPGWEPRSESQASRKEEGLPEEEPSHVTGREGFP
TDAPYPTTLGKDRECQSQSLALKEQNNLKQLEFGLKEAPVQDQGYKTLRLGENCVLSSSPNPFP
EISRGEYLYTYNSQITDSEHNSSLVSQQTGSPGKQPGENSDCHRDSSQAIPIMELTKSQVQDKP
YKCTDCGKSFNHNAHLTVHKRIHTGERPYMCKECGKAFSQNSSLVQHERIHTGDKPYKCAECGK
SFCHSTHLTVHRRIHTGEKPYECQDCGRAFNQNSSLGRHKRTHTGEKPYTCSVCGKSFSRTTCL
FLHLRTHTEERPYECNHCGKGFRHSSSLAQHQRKHAGEKPFECRQRLIFEQTPALTKHEWTEAL
GCDPPLSQDERTHRSDRPFKCNQCGKCFIQSSHLIRHQITHTREEQPHGRSRRREQSSSRNSHL
VQHQHSNSRKSSAGGAKAGQPESRALALFDIQKIMQEKNPVHVIGVEEPSVGASMLFDIREST

hide sequence

RefSeq Acc Id:

ENSPPAP00000013119 ⟸ ENSPPAT00000035787

Protein Domains

C2H2-type KRAB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000029724	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000035787.1	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	KRAB	UniProtKB/TrEMBL
	KRAB_dom_sf	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
KEGG Report	pps:100977240	UniProtKB/TrEMBL
NCBI Gene	ZNF8	ENTREZGENE
PANTHER	KRAB DOMAIN C2H2 ZINC FINGER	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 8	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PROSITE	KRAB	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	KRAB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF109640	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A0A2R9A750	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-06-11	ZNF8	zinc finger protein 8	LOC106634154	uncharacterized LOC106634154	Data merged from RGD:12046180	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar