CDT1 (chromatin licensing and DNA replication factor 1) - Rat Genome Database

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Gene: CDT1 (chromatin licensing and DNA replication factor 1) Pan paniscus
Analyze
Symbol: CDT1
Name: chromatin licensing and DNA replication factor 1
RGD ID: 11764183
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA polymerase binding (inferred); INVOLVED IN regulation of nuclear cell cycle DNA replication (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); adenine phosphoribosyltransferase deficiency (ortholog); autosomal recessive chronic granulomatous disease 4 (ortholog); FOUND IN kinetochore (inferred); nuclear body (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA replication factor Cdt1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,576,543 - 98,582,287 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,488,752 - 104,494,459 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,516,728 - 69,522,419 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,173,312 - 89,178,809 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,174,071 - 89,177,823 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
kinetochore  (IEA)
nuclear body  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,576,543 - 98,582,287 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,488,752 - 104,494,459 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,516,728 - 69,522,419 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,173,312 - 89,178,809 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,174,071 - 89,177,823 (+)Ensemblpanpan1.1panPan2
CDT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,803,789 - 88,809,258 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,803,789 - 88,809,258 (+)EnsemblGRCh38hg38GRCh38
GRCh371688,870,197 - 88,875,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,397,687 - 87,403,167 (+)NCBINCBI36Build 36hg18NCBI36
Celera1673,938,823 - 73,944,303 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,567,412 - 74,572,892 (+)NCBIHuRef
CHM1_11690,281,453 - 90,286,933 (+)NCBICHM1_1
T2T-CHM13v2.01694,874,309 - 94,879,778 (+)NCBIT2T-CHM13v2.0
Cdt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,294,754 - 123,299,869 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,294,754 - 123,300,293 (+)EnsemblGRCm39 Ensembl
GRCm388122,568,015 - 122,573,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,568,015 - 122,573,554 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,091,915 - 125,097,030 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,454,105 - 125,459,220 (+)NCBIMGSCv36mm8
Celera8126,797,613 - 126,802,728 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.91NCBI
Cdt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,529,249 - 67,534,195 (+)NCBIGRCr8
mRatBN7.21950,620,713 - 50,625,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,620,713 - 50,625,659 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,415,480 - 57,420,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,095,635 - 58,100,581 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,314,104 - 60,319,053 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,381,565 - 55,386,511 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,381,565 - 55,386,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,090,081 - 66,095,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,848,559 - 52,853,880 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,852,915 - 52,858,234 (+)NCBI
Celera1949,860,119 - 49,865,065 (+)NCBICelera
Cytogenetic Map19q12NCBI
Cdt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,683,408 - 2,687,102 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,683,030 - 2,687,883 (+)NCBIChiLan1.0ChiLan1.0
CDT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,566,035 - 64,570,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,566,043 - 64,570,748 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,577,507 - 64,581,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,786,263 - 64,790,545 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,786,266 - 64,790,971 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,812,442 - 64,816,851 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,643,948 - 64,648,365 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,049,993 - 65,054,410 (-)NCBIUU_Cfam_GSD_1.0
Cdt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,163,147 - 25,172,972 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641917,435 - 920,981 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641916,695 - 925,411 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6893,381 - 897,934 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16893,377 - 897,706 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.261,083,762 - 1,089,922 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,190,409 - 74,196,589 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,190,947 - 74,195,972 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,482,389 - 1,488,114 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746809,252 - 812,993 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746808,463 - 813,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034940911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000047760   ⟹   ENSPPAP00000024934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1689,174,071 - 89,177,823 (+)Ensembl
RefSeq Acc Id: XM_034940911   ⟹   XP_034796802
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21898,576,543 - 98,582,287 (+)NCBI
NHGRI_mPanPan116104,488,752 - 104,494,459 (+)NCBI
Mhudiblu_PPA_v01669,516,728 - 69,522,419 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034796802 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024934.1
Reference Protein Sequences
RefSeq Acc Id: XP_034796802   ⟸   XM_034940911
- UniProtKB: A0A2R9BCW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000024934   ⟸   ENSPPAT00000047760
Protein Domains
CDT1 Geminin-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035604 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047760.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1420 UniProtKB/TrEMBL
InterPro Cdt1 UniProtKB/TrEMBL
  Cdt1_C UniProtKB/TrEMBL
  Cdt1_C_WH_dom_sf UniProtKB/TrEMBL
  CDT1_Gemini-bd-like UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene CDT1 ENTREZGENE
PANTHER DNA REPLICATION FACTOR CDT1 UniProtKB/TrEMBL
  PTHR28637 UniProtKB/TrEMBL
Pfam CDT1 UniProtKB/TrEMBL
  CDT1_C UniProtKB/TrEMBL
SMART CDT1 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A2R9BCW7 ENTREZGENE, UniProtKB/TrEMBL