NCKAP1L (NCK associated protein 1 like) - Rat Genome Database

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Gene: NCKAP1L (NCK associated protein 1 like) Pan paniscus
Analyze
Symbol: NCKAP1L
Name: NCK associated protein 1 like
RGD ID: 11764008
Description: ENCODES a protein that exhibits GTPase activator activity (ortholog); protein kinase activator activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN actin polymerization-dependent cell motility (ortholog); B cell homeostasis (ortholog); B cell receptor signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); immunodeficiency 72 (ortholog); FOUND IN cytosol (ortholog); SCAR complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: nck-associated protein 1-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11234,932,470 - 34,977,881 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1234,932,470 - 34,977,881 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01234,200,102 - 34,249,873 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin polymerization-dependent cell motility  (ISO)
B cell homeostasis  (ISO)
B cell receptor signaling pathway  (ISO)
chemotaxis  (ISO)
cortical actin cytoskeleton organization  (ISO)
erythrocyte development  (ISO)
erythrocyte homeostasis  (ISO)
maintenance of cell polarity  (ISO)
myeloid cell homeostasis  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cytotoxic T cell degranulation  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of myosin-light-chain-phosphatase activity  (ISO)
neutrophil chemotaxis  (ISO)
positive regulation of actin filament polymerization  (ISO)
positive regulation of B cell differentiation  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of CD4-positive, alpha-beta T cell differentiation  (ISO)
positive regulation of CD8-positive, alpha-beta T cell differentiation  (ISO)
positive regulation of cell adhesion mediated by integrin  (ISO)
positive regulation of erythrocyte differentiation  (ISO)
positive regulation of gamma-delta T cell differentiation  (ISO)
positive regulation of leukocyte migration  (ISO)
positive regulation of lymphocyte differentiation  (ISO)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of neutrophil migration  (ISO)
positive regulation of phagocytosis, engulfment  (ISO)
positive regulation of phosphorylation  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of TORC2 signaling  (ISO)
protein-containing complex assembly  (ISO)
response to drug  (ISO)
T cell homeostasis  (ISO)

Cellular Component
cytosol  (ISO)
SCAR complex  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
NCKAP1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11234,932,470 - 34,977,881 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1234,932,470 - 34,977,881 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01234,200,102 - 34,249,873 (-)NCBIMhudiblu_PPA_v0panPan3
NCKAP1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1254,497,752 - 54,548,243 (+)EnsemblGRCh38hg38GRCh38
GRCh381254,497,752 - 54,548,243 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371254,891,536 - 54,942,027 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,177,762 - 53,223,166 (+)NCBINCBI36hg18NCBI36
Build 341253,177,779 - 53,223,160NCBI
Celera1254,543,329 - 54,588,759 (+)NCBI
Cytogenetic Map12q13.13-q13.2NCBI
HuRef1251,930,257 - 51,975,669 (+)NCBIHuRef
CHM1_11254,858,206 - 54,903,614 (+)NCBICHM1_1
Nckap1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,362,219 - 103,411,288 (+)NCBIGRCm39mm39
GRCm39 Ensembl15103,362,221 - 103,407,237 (+)Ensembl
GRCm3815103,453,783 - 103,502,860 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,453,794 - 103,498,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715103,284,256 - 103,329,231 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615103,281,859 - 103,326,834 (+)NCBImm8
Celera15105,611,951 - 105,656,787 (+)NCBICelera
Cytogenetic Map15F3NCBI
Nckap1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,577,443 - 134,622,934 (+)NCBI
Rnor_6.0 Ensembl7145,068,286 - 145,113,507 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07145,068,239 - 145,113,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07142,849,455 - 142,894,585 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,351,954 - 142,397,045 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17142,432,180 - 142,475,970 (+)NCBI
Celera7131,001,894 - 131,046,866 (+)NCBICelera
Cytogenetic Map7q36NCBI
Nckap1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,733,883 - 1,784,182 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554581,733,799 - 1,785,591 (+)NCBIChiLan1.0ChiLan1.0
NCKAP1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127805,274 - 858,901 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl27805,310 - 843,439 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2745,396,099 - 45,449,340 (+)NCBI
ROS_Cfam_1.027802,738 - 856,041 (-)NCBI
UMICH_Zoey_3.127795,107 - 848,346 (-)NCBI
UNSW_CanFamBas_1.027803,528 - 857,308 (-)NCBI
UU_Cfam_GSD_1.02745,799,997 - 45,853,537 (+)NCBI
Nckap1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,430,392 - 61,521,726 (-)NCBI
SpeTri2.0NW_00493651211,683,330 - 11,734,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCKAP1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,677,875 - 19,723,132 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1519,677,613 - 19,720,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NCKAP1L
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,611,193 - 50,658,800 (+)NCBI
Vero_WHO_p1.0NW_023666037195,373,507 - 195,426,134 (-)NCBI
Nckap1l
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249042,508,576 - 2,575,505 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003807564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000054493   ⟹   ENSPPAP00000031628
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1234,932,470 - 34,977,881 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054504   ⟹   ENSPPAP00000031639
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1234,932,876 - 34,977,802 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054511   ⟹   ENSPPAP00000031646
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1234,932,876 - 34,977,802 (-)Ensembl
RefSeq Acc Id: XM_003807564   ⟹   XP_003807612
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11234,932,470 - 34,977,881 (-)NCBI
Mhudiblu_PPA_v01234,200,102 - 34,249,873 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003807612 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003807612   ⟸   XM_003807564
- Sequence:
RefSeq Acc Id: ENSPPAP00000031639   ⟸   ENSPPAT00000054504
RefSeq Acc Id: ENSPPAP00000031646   ⟸   ENSPPAT00000054511
RefSeq Acc Id: ENSPPAP00000031628   ⟸   ENSPPAT00000054493


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038716 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000031628 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000031639 UniProtKB/TrEMBL
  ENSPPAP00000031646 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054493 UniProtKB/TrEMBL
  ENSPPAT00000054504 UniProtKB/TrEMBL
  ENSPPAT00000054511 UniProtKB/TrEMBL
InterPro Nck-associated_protein-1 UniProtKB/TrEMBL
KEGG Report pps:100996138 UniProtKB/TrEMBL
NCBI Gene NCKAP1L ENTREZGENE
PANTHER PTHR12093 UniProtKB/TrEMBL
Pfam Nckap1 UniProtKB/TrEMBL
UniProt A0A2R9BPR5_PANPA UniProtKB/TrEMBL
  A0A2R9BQF0_PANPA UniProtKB/TrEMBL
  A0A2R9BT51_PANPA UniProtKB/TrEMBL