RNF213 (ring finger protein 213) - Rat Genome Database

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Gene: RNF213 (ring finger protein 213) Pan paniscus
Analyze
Symbol: RNF213
Name: ring finger protein 213
RGD ID: 11763396
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN angiogenesis (ortholog); defense response to bacterium (ortholog); lipid droplet formation (ortholog); ASSOCIATED WITH anaplastic ependymoma (ortholog); Aortic Coarctation (ortholog); epilepsy (ortholog); FOUND IN cytosol (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF213
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21996,840,037 - 96,976,100 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117101,739,813 - 101,874,913 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01774,688,130 - 74,823,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11780,421,373 - 80,556,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1780,421,373 - 80,556,570 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA,ISO)
lipid droplet  (ISO)
membrane  (IEA)
nucleolus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF213
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21996,840,037 - 96,976,100 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117101,739,813 - 101,874,913 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01774,688,130 - 74,823,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11780,421,373 - 80,556,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1780,421,373 - 80,556,570 (+)Ensemblpanpan1.1panPan2
RNF213
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381780,260,852 - 80,398,794 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1780,260,852 - 80,398,794 (+)EnsemblGRCh38hg38GRCh38
GRCh371778,234,651 - 78,372,594 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361775,928,321 - 75,984,681 (+)NCBINCBI36Build 36hg18NCBI36
Celera1774,864,699 - 74,998,227 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1773,676,973 - 73,810,563 (+)NCBIHuRef
CHM1_11778,320,628 - 78,458,825 (+)NCBICHM1_1
T2T-CHM13v2.01781,161,115 - 81,300,623 (+)NCBIT2T-CHM13v2.0
Rnf213
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911119,280,778 - 119,378,245 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11119,283,926 - 119,378,244 (+)EnsemblGRCm39 Ensembl
GRCm3811119,389,950 - 119,487,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11119,393,100 - 119,487,418 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711119,254,414 - 119,348,739 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611119,342,115 - 119,348,729 (+)NCBIMGSCv36mm8
Celera11131,141,037 - 131,235,450 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.48NCBI
Rnf213
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810105,154,873 - 105,254,148 (+)NCBIGRCr8
mRatBN7.210104,656,329 - 104,755,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,656,883 - 104,757,918 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.010108,527,351 - 108,626,372 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,527,740 - 108,624,688 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010108,134,305 - 108,230,724 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,765,490 - 108,862,935 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110108,778,807 - 108,875,755 (+)NCBI
Celera10103,204,438 - 103,300,991 (+)NCBICelera
Cytogenetic Map10q32.3NCBI
Rnf213
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555062,499,770 - 2,596,989 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555062,498,339 - 2,598,363 (-)NCBIChiLan1.0ChiLan1.0
RNF213
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.191,439,061 - 1,506,658 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl91,440,364 - 1,506,951 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha92,056,478 - 2,154,125 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.092,048,400 - 2,146,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl92,047,972 - 2,145,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.192,071,964 - 2,170,024 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.092,197,505 - 2,295,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.092,278,468 - 2,376,800 (-)NCBIUU_Cfam_GSD_1.0
Rnf213
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056022,082,963 - 2,171,115 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365944,241,396 - 4,331,868 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365944,241,006 - 4,331,841 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF213
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11672,241,519 - 72,370,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1672,244,245 - 72,369,859 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607743,548,858 - 43,678,882 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf213
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248019,472,891 - 9,574,511 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000017400   ⟹   ENSPPAP00000003773
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1780,421,373 - 80,556,570 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000017412   ⟹   ENSPPAP00000003776
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1780,421,373 - 80,556,570 (+)Ensembl
RefSeq Acc Id: XM_003831141   ⟹   XP_003831189
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,057 - 96,976,100 (+)NCBI
NHGRI_mPanPan117101,739,840 - 101,874,913 (+)NCBI
Mhudiblu_PPA_v01774,688,234 - 74,823,973 (+)NCBI
PanPan1.11780,421,373 - 80,556,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008956536   ⟹   XP_008954784
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,056 - 96,976,100 (+)NCBI
NHGRI_mPanPan117101,739,838 - 101,874,913 (+)NCBI
Mhudiblu_PPA_v01774,688,131 - 74,823,973 (+)NCBI
PanPan1.11780,421,373 - 80,556,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008956539   ⟹   XP_008954787
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,042 - 96,965,850 (+)NCBI
NHGRI_mPanPan117101,739,813 - 101,865,597 (+)NCBI
Mhudiblu_PPA_v01774,688,130 - 74,813,683 (+)NCBI
PanPan1.11780,421,373 - 80,546,313 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055101595   ⟹   XP_054957570
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,388 - 96,976,100 (+)NCBI
NHGRI_mPanPan117101,740,196 - 101,874,913 (+)NCBI
RefSeq Acc Id: XM_063599452   ⟹   XP_063455522
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,393 - 96,976,100 (+)NCBI
RefSeq Acc Id: XM_063599453   ⟹   XP_063455523
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,870,362 - 96,976,100 (+)NCBI
RefSeq Acc Id: XM_063599454   ⟹   XP_063455524
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21996,840,037 - 96,961,794 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008954784   ⟸   XM_008956536
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003831189   ⟸   XM_003831141
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008954787   ⟸   XM_008956539
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSPPAP00000003776   ⟸   ENSPPAT00000017412
RefSeq Acc Id: ENSPPAP00000003773   ⟸   ENSPPAT00000017400
RefSeq Acc Id: XP_054957570   ⟸   XM_055101595
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063455524   ⟸   XM_063599454
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063455522   ⟸   XM_063599452
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063455523   ⟸   XM_063599453
- Peptide Label: isoform X4
Protein Domains
RING-type   RZ-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000015826 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000017400.1 UniProtKB/TrEMBL
  ENSPPAT00000017412.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNF213 UniProtKB/TrEMBL
  ZF_RZ_dom UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report pps:100978355 UniProtKB/TrEMBL
NCBI Gene RNF213 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF213 UniProtKB/TrEMBL
  PTHR22605 UniProtKB/TrEMBL
Pfam DUF6539 UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
  ZF_RZ UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZFI2_PANPA UniProtKB/TrEMBL
  A0A2R8ZLY8_PANPA UniProtKB/TrEMBL