CYP2B6 (cytochrome P450 family 2 subfamily B member 6)

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Gene: CYP2B6 (cytochrome P450 family 2 subfamily B member 6) Pan paniscus

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Symbol:

CYP2B6

Name:

cytochrome P450 family 2 subfamily B member 6

RGD ID:

11761018

Description:

ENCODES a protein that exhibits anandamide 11,12 epoxidase activity (inferred); anandamide 14,15 epoxidase activity (inferred); anandamide 8,9 epoxidase activity (inferred); INVOLVED IN response to Aroclor 1254 (ortholog); response to bacterium (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); acute myeloid leukemia (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cytochrome P450 2B6; LOC100984180

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	47,220,446 - 47,246,316 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	49,088,771 - 49,114,653 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	38,003,083 - 38,028,980 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	46,509,370 - 46,534,672 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	46,509,370 - 46,534,672 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Lymphoblastic Leukemia, with Lymphomatous Features (ISO)

acute myeloid leukemia (ISO)

autism spectrum disorder (ISO)

Carpenter Syndrome 2 (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

congenital hypoplastic anemia (ISO)

craniosynostosis 1 (ISO)

Diamond-Blackfan anemia (ISO)

drug dependence (ISO)

Drug Overdose (ISO)

Efavirenz, Poor Metabolism of (ISO)

end stage renal disease (ISO)

Experimental Diabetes Mellitus (ISO)

gliosarcoma (ISO)

hepatocellular carcinoma (ISO)

heroin dependence (ISO)

human immunodeficiency virus infectious disease (ISO)

maple syrup urine disease (ISO)

Metabolic Side Effects of Drugs and Substances (ISO)

neonatal abstinence syndrome (ISO)

nicotine dependence (ISO)

tuberculosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

epoxygenase P450 pathway (IEA)

ketone metabolic process (IEA)

response to Aroclor 1254 (ISO)

response to bacterium (ISO)

steroid metabolic process (IEA)

xenobiotic catabolic process (IEA)

xenobiotic metabolic process (IEA)

Cellular Component

cytoplasm (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

intracellular membrane-bounded organelle (IEA)

Molecular Function

anandamide 11,12 epoxidase activity (IEA)

anandamide 14,15 epoxidase activity (IEA)

anandamide 8,9 epoxidase activity (IEA)

arachidonate epoxygenase activity (IEA)

estrogen 2-hydroxylase activity (IEA)

heme binding (IEA)

iron ion binding (IEA)

metal ion binding (IEA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (IEA)

testosterone 16-alpha-hydroxylase activity (IEA)

testosterone 16-beta-hydroxylase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylsalicylic acid pharmacodynamics pathway (ISO)

antipyrine drug pathway (ISO)

arachidonic acid metabolic pathway (ISO)

carbamazepine pharmacokinetics pathway (ISO)

celecoxib pharmacodynamics pathway (ISO)

clopidogrel pharmacodynamics pathway (ISO)

clopidogrel pharmacokinetics pathway (ISO)

cyclophosphamide pharmacodynamics pathway (ISO)

cyclophosphamide pharmacokinetics pathway (ISO)

diclofenac pharmacodynamics pathway (ISO)

diflunisal pharmacodynamics pathway (ISO)

etodolac pharmacodynamics pathway (ISO)

fenoprofen pharmacodynamics pathway (ISO)

flurbiprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

ifosfamide pharmacodynamics pathway (ISO)

ifosfamide pharmacokinetics pathway (ISO)

indometacin pharmacodynamics pathway (ISO)

ketoprofen pharmacodynamics pathway (ISO)

ketorolac pharmacodynamics pathway (ISO)

leukotriene C4 synthase deficiency pathway (ISO)

lornoxicam pharmacodynamics pathway (ISO)

magnesium salicylate pharmacodynamics pathway (ISO)

mefenamic acid pharmacodynamics pathway (ISO)

meloxicam pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

methadone pharmacokinetics pathway (ISO)

nabumetone pharmacodynamics pathway (ISO)

naproxen pharmacodynamics pathway (ISO)

neviparine pharmacokinetics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

nicotine pharmacokinetics pathway (ISO)

organophosphate response pathway (ISO)

paracetamol drug pathway (ISO)

piroxicam pharmacodynamics pathway (ISO)

retinol metabolic pathway (ISO)

salicylic acid pharmacodynamics pathway (ISO)

sodium salicylate pharmacodynamics pathway (ISO)

sorafenib pharmacokinetics pathway (ISO)

sulindac pharmacodynamics pathway (ISO)

tamoxifen pharmacodynamics pathway (ISO)

tamoxifen pharmacokinetics pathway (ISO)

tenoxicam pharmacodynamics pathway (ISO)

tiaprofenic acid pharmacodynamics pathway (ISO)

tolmetin pharmacodynamics pathway (ISO)

tramadol pharmacokinetics pathway (ISO)

valdecoxib pharmacodynamics pathway (ISO)

valproic acid pharmacokinetics pathway (ISO)

vitamin A deficiency pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CYP2B6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	47,220,446 - 47,246,316 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	49,088,771 - 49,114,653 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	38,003,083 - 38,028,980 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	46,509,370 - 46,534,672 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	46,509,370 - 46,534,672 (+)	Ensembl	panpan1.1		panPan2

CYP2B6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	40,991,282 - 41,018,398 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	40,991,282 - 41,018,398 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	41,497,187 - 41,524,303 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	46,189,044 - 46,216,141 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	46,189,043 - 46,216,141	NCBI
Celera	19	38,297,361 - 38,324,463 (+)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	37,929,211 - 37,956,335 (+)	NCBI		HuRef
CHM1_1	19	41,496,934 - 41,524,020 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	43,812,191 - 43,839,297 (+)	NCBI		T2T-CHM13v2.0

Cyp2b10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	25,597,083 - 25,626,049 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	25,597,045 - 25,626,049 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	25,897,658 - 25,926,624 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	25,897,620 - 25,926,624 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	26,682,683 - 26,711,643 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	25,606,424 - 25,635,384 (+)	NCBI		MGSCv36	mm8
Celera	7	20,506,748 - 20,536,205 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	14.11	NCBI

Cyp2b3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	90,780,468 - 90,859,852 (+)	NCBI		GRCr8
mRatBN7.2	1	81,652,762 - 81,732,153 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	81,652,787 - 81,732,143 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	87,073,523 - 87,141,243 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	95,571,804 - 95,642,315 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	88,829,353 - 88,897,077 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	83,163,103 - 83,236,615 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	83,163,079 - 83,236,615 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	84,445,481 - 84,491,180 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	81,084,984 - 81,185,251 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	81,486,546 - 81,659,871 (+)	NCBI
Celera	1	76,082,604 - 76,158,885 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

CYP2B6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	112,817,561 - 112,833,294 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	112,816,502 - 112,833,293 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	112,220,751 - 112,236,323 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	113,415,892 - 113,431,675 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	113,415,766 - 113,431,674 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	112,976,144 - 112,991,691 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	112,607,509 - 112,623,091 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	113,602,017 - 113,617,585 (+)	NCBI		UU_Cfam_GSD_1.0

CYP2B6B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	49,110,812 - 49,178,334 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	49,158,175 - 49,173,872 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	44,968,257 - 44,978,794 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYP2B6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	35,392,699 - 35,418,171 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	35,393,342 - 35,418,106 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	13,588,241 - 13,611,993 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014342682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000039913 ⟹ ENSPPAP00000017212

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	46,509,370 - 46,534,672 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000039919 ⟹ ENSPPAP00000017218

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	46,520,953 - 46,533,617 (+)	Ensembl

RefSeq Acc Id:

XM_014342682 ⟹ XP_014198168

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	47,220,446 - 47,246,316 (+)	NCBI
NHGRI_mPanPan1	19	49,088,771 - 49,114,653 (+)	NCBI
Mhudiblu_PPA_v0	19	38,003,083 - 38,028,980 (+)	NCBI
PanPan1.1	19	46,509,370 - 46,534,672 (+)	NCBI

Sequence:

show sequence

CAGACCAGGACCATGGAACTCAGCGTCCTCCTCTTCCTTGCACTCCTCACAGGACTCTTGCTAC
TCCTGGTTCAGCGCCACCCTAACACCCATGGCCGCCTCCCACCAGGGCCCCGCCCTCTGCCCCT
TTTGGGGAACCTTCTGCAGATGGATAGAAGAGGCCTACTCAAATCCTTTCTGAGGTTCCGAGAG
AAATATGGGGACGTCTTCACGGTACACCTGGGACCGAGGCCCGTGGTCATGCTGTGTGGAGTAG
AGGCCATACGGGAGGCCCTGGTGGACAAGGCTGAGGCCTTCTCTGGCCGGGGAAAAATCGCCAT
GGTCGACCCATTCTTCCGGGGATATGGTGTGATCTTTGCCAATGGAAACCGCTGGAAGGTGCTT
CGGCGATTCTCTGTGACCACCATGAGGGACTTCGGGATGGGAAAGCGGAGTGTGGAGGAGCGGA
TTCAGGAGGAGGCTCAGTGTCTGATAGAGGAACTTCGGAAATCCAAGGGAGCCCTCATGGACCC
CACCTTCCTCTTCCAGTCCATTACCGCCAACATCATCTGCTCCATCGTCTTTGGAAAACGATTC
CACTACCAAGATCAAGAGTTCCTGAAGATGCTGAACTTATTCTACCAGACTTTTTCACTCGTCA
GCTCTGTATTCGGCCAGCTGTTTGAGCTCTTCTCTGGCTTCTTGAAATACTTTCCTGGGGCACA
CAGGCAAGTTTACAAAAACCTTCAGGAAATCAATGCTTACATTGGCCACAGTGTGGAGAAGCAC
CGTGAAACCCTGGACCCCAGCGCCCCCAAGGACCTCATCGACACCTACCTGCTCCACATGGAAA
AAGAGAAATCCGACGCACACAGTGAATTCAGCCACCAGAACCTCACCCTCAACACGCTCTCGCT
CTTCTTTGCTGGCACTGAGACCACCAGCACCACTCTCCGCTACGGCTTCCTGCTCATGCTCAAA
TACCCTCATGTTGCAGAGAGAGTCTACAGGGAGATTGAACAGGTGATTGGCCCACATCGCCCTC
CAGAGCTTCATGACCGAGCCAAAATGCCATACACAGAGGCAGTCATCTATGAGATTCAGAGATT
TTCTGACCTTCTCCCCATGGGTGTGCCCCACATTGTCACCCAACACACCAGCTTCCGAGGATAC
ATCATCCCCAAGGACACGGAAGTATTTCTTATCCTGAGCACTGCTCTCCATGACCCACACTACT
TTGAAAAACCAGACGCCTTCAATCCTGACCACTTTCTGGATGCCAATGGGGCGCTGAAAAAGAA
TGAAGCTTTTATTCCCTTCTCCTTAGGGAAGCGGATTTGTCTTGGTGAAGGCATCGCCCGTGCT
GAATTGTTCCTCTTCTTCACCACCATCCTCCAGAACTTCTCCGTGGCCAGCCCCGAGGCCCCAG
AAGACATCGATCTGACACCCCAGGAGTGTGGTGTGGGAAAAATACCCCCAACATACCAGATCCG
CTTCCTGCCCCGCTGAAGGGGCTGAGGGAAGGGGGTCAAAGGATTCCAGGGTCATTCAGTGTCC
CCGCCTCTGTAGACAATGGCTCTGACTCCCCGCAACTTCCTGCCTCTGAGAGACCTGCTGCAAG
CCAGCTTCCTTCCCCGCCATGGCACCAGTTGTCTGAGGTCACATTGCAAGTGAGTGCAGGAGTG
AGATTATTGAAAAATTATAATATACAAAATCATATATATATATATGTTCTTGTTTTTTGAGACA
GAGTCTCACACTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAACCTCCAC
CCCCGGGGTTCAAGCAACTCTCCTGCCTCAGCCTCCCTAGTAGCCAGGATTACAGGCATGCACT
ACCACGCTTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTAGGCCAGGCTGG
TCTCGAACTCCTGAACTCAAGTGATTCACCCACGTTAGCCTCCCAAAGTGCTGGGATTACAGGC
GTGAGTCACCGTGCCCAGCCATGTATATATATAATTTGAAAAATTAAGCTGAAATTCACATAAC
ACAAAATTAGCCGTTTTAAAGTGTAAAATTTAGTGGCGTGTGGTTCATTCACAAAGCTGTACAA
CCACCACCATCTAGTTCCAAACATTTTCTTTTTTTCTGAGATGGAGTCTCACTCTGTCACCCAG
GCTCGAGTTCAGTGGTGCCATCTCTGTCCACTGCAACCTCCACATCCTGGGTTCAAGTGATTCT
CCTGCCTCAGCCTCTGGAGGAGCTGGGATCACAGGCGTCCCCCACCATGCCTGGCTAAATTTTG
TATTTTTAGGTGGTCTTGAACTCCTGATGTCAGGTGATTCTCCTAGCTCCAAATGTTTTCATTA
TCTCCCCCCCAACAAAACCCATACCTATCAAGCTGTCACTCCCCATACCCCATTCTCTTTTTCA
TCTCAGCCCCTGTCAATCTGGTTTTTGTCACTATGGACTTACCAATTCTGAATATTTCCCATAA
ACAGAATCATACAATATTTGATTTTTTTTTTTTTGAAACTAAGCCTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_014198168	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000017212.1
	ENSPPAP00000017218.1

RefSeq Acc Id:

XP_014198168 ⟸ XM_014342682

- UniProtKB:

A0A2R9AIM3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MELSVLLFLALLTGLLLLLVQRHPNTHGRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGD
VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFS
VTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQD
QEFLKMLNLFYQTFSLVSSVFGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETL
DPSAPKDLIDTYLLHMEKEKSDAHSEFSHQNLTLNTLSLFFAGTETTSTTLRYGFLLMLKYPHV
AERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPK
DTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKNEAFIPFSLGKRICLGEGIARAELFL
FFTTILQNFSVASPEAPEDIDLTPQECGVGKIPPTYQIRFLPR

hide sequence

Ensembl Acc Id:

ENSPPAP00000017218 ⟸ ENSPPAT00000039919

Ensembl Acc Id:

ENSPPAP00000017212 ⟸ ENSPPAT00000039913

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000031682	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000039913.1	UniProtKB/TrEMBL
	ENSPPAT00000039919.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I_CYP2B-like	UniProtKB/TrEMBL
	Cyt_P450_E_grp-IV	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
	Cytochrome_P450_fam2	UniProtKB/TrEMBL
KEGG Report	pps:100984180	UniProtKB/TrEMBL
NCBI Gene	LOC100984180	ENTREZGENE
PANTHER	CYTOCHROME P450 2B6	UniProtKB/TrEMBL
	CYTOCHROME P450 508A4-RELATED	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	EP450ICYP2B	UniProtKB/TrEMBL
	EP450IV	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A0A2R9AIM3	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AJI2_PANPA	UniProtKB/TrEMBL
VGNC ID	VGNC:83043	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-02-25	CYP2B6	cytochrome P450 family 2 subfamily B member 6	LOC100984180	cytochrome P450 2B6	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB