LARP7 (La ribonucleoprotein 7, transcriptional regulator)

Gene: LARP7 (La ribonucleoprotein 7, transcriptional regulator) Pan paniscus

Analyze

Symbol:

LARP7

Name:

La ribonucleoprotein 7, transcriptional regulator

RGD ID:

11760880

Description:

ENCODES a protein that exhibits 7SK snRNA binding (inferred); RNA binding (inferred); U6 snRNA binding (inferred); INVOLVED IN germ cell proliferation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of G1/S transition of mitotic cell cycle (ortholog); ASSOCIATED WITH Alazami Syndrome (ortholog); Alazami-Yuan Syndrome (ortholog); aniridia (ortholog); FOUND IN 7SK snRNP (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

La ribonucleoprotein domain family member 7; la-related protein 7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	110,714,437 - 110,735,586 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	111,007,851 - 111,029,020 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	105,128,335 - 105,149,498 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	115,690,359 - 115,711,263 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	115,698,093 - 115,711,003 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alazami Syndrome (ISO)

Alazami-Yuan Syndrome (ISO)

aniridia (ISO)

Axenfeld-Rieger syndrome type 1 (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

box C/D sno(s)RNA 3'-end processing (IEA)

cell differentiation (IEA)

germ cell proliferation (ISO)

mRNA processing (IEA)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

negative regulation of viral transcription (IEA)

positive regulation of G1/S transition of mitotic cell cycle (ISO)

positive regulation of protein localization to Cajal body (IEA)

positive regulation of snRNA transcription by RNA polymerase II (IEA)

regulation of mRNA splicing, via spliceosome (IEA)

RNA processing (IEA)

RNA splicing (IEA)

spermatogenesis (ISO)

U6 2'-O-snRNA methylation (IEA)

Cellular Component

7SK snRNP (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

ribonucleoprotein complex (IEA)

Molecular Function

7SK snRNA binding (IEA)

protein binding (ISO)

RNA binding (IEA)

U6 snRNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LARP7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	110,714,437 - 110,735,586 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	111,007,851 - 111,029,020 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	105,128,335 - 105,149,498 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	115,690,359 - 115,711,263 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	115,698,093 - 115,711,003 (+)	Ensembl	panpan1.1		panPan2

LARP7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	112,637,143 - 112,657,586 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	112,637,077 - 112,657,696 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	113,558,299 - 113,578,742 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	113,777,569 - 113,798,191 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	110,852,197 - 110,872,835 (+)	NCBI		Celera
Cytogenetic Map	4	q25	NCBI
HuRef	4	109,286,524 - 109,307,168 (+)	NCBI		HuRef
CHM1_1	4	113,534,600 - 113,555,241 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	115,945,482 - 115,965,926 (+)	NCBI		T2T-CHM13v2.0

Larp7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	127,330,363 - 127,346,998 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	127,330,363 - 127,346,998 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	127,536,714 - 127,553,349 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	127,536,714 - 127,553,349 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	127,239,632 - 127,256,267 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	127,528,736 - 127,536,271 (-)	NCBI		MGSCv36	mm8
Celera	3	134,026,262 - 134,045,696 (-)	NCBI		Celera
Cytogenetic Map	3	G2	NCBI
cM Map	3	56.54	NCBI

Larp7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	218,672,145 - 218,687,332 (-)	NCBI		GRCr8
mRatBN7.2	2	215,997,641 - 216,012,833 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	215,997,649 - 216,012,865 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	223,661,815 - 223,676,912 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	221,561,674 - 221,576,771 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	216,416,573 - 216,431,677 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	231,866,888 - 231,882,002 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	231,867,135 - 231,881,939 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	251,212,469 - 251,227,583 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	2	208,314,421 - 208,329,446 (-)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

Larp7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	14,178,947 - 14,192,193 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955457	14,178,674 - 14,200,164 (-)	NCBI	ChiLan1.0	ChiLan1.0

LARP7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	32,421,648 - 32,439,431 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	32,421,675 - 32,439,131 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	9,592,325 - 9,610,142 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	32,647,426 - 32,665,234 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	32,647,840 - 32,665,239 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	32,630,137 - 32,647,867 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	32,392,041 - 32,409,799 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	7,450,765 - 7,468,554 (-)	NCBI		UU_Cfam_GSD_1.0

Larp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	8,434,294 - 8,454,181 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936563	3,455,045 - 3,475,417 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936563	3,455,205 - 3,474,955 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LARP7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	110,069,829 - 110,089,708 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	110,069,565 - 110,089,789 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	115,189,078 - 115,208,643 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LARP7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	60,407,137 - 60,429,885 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	60,406,618 - 60,430,080 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	39,166,011 - 39,188,617 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Larp7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624838	6,413,494 - 6,425,939 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624838	6,331,393 - 6,426,151 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008955400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055111724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055111725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063603573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000053818 ⟹ ENSPPAP00000030954

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	4	115,698,093 - 115,711,003 (+)	Ensembl

RefSeq Acc Id:

XM_008955400 ⟹ XP_008953648

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,798 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,008,212 - 111,029,020 (+)	NCBI
Mhudiblu_PPA_v0	4	105,128,687 - 105,149,498 (+)	NCBI
PanPan1.1	4	115,690,359 - 115,711,263 (+)	NCBI

Sequence:

show sequence

CATAGGGGCCCGGCGTGGGGAGGTTTGGGGCGCGCCCAGCCTATGACGGCGTCCTTGCGGAAGT
ACGGGTGCCGAGAGAAGCAGTAGTCAATAAAGAGAGTGCCGTATTTCGCAGATTGGAGCTGAGC
TGTGGCTGCCAGAGGATAGCGAACGAATGGAAACTGAAAGTGGAAATCAGGAAAAGGTAATGGA
AGAAGAAAGCACTGAAAAGAAAAAAGAAGTTGAAAAAAAGAAACGGTCACGAGTTAAACAGGTG
CTTGCAGATATTGCTAAGCAAGTGGACTTCTGGTTTGGGGATGCAAATCTTCACAAGGATAGAT
TTCTTCGAGAACAGATAGAAAAATCTAGAGATGGATATGTTGATATATCACTACTTGTGTCTTT
TAACAAAATGAAAAAATTGACTACTGATGGGAAGTTAATTGCCAGAGCATTGAGAAGTTCAGCT
GTTGTAGAGCTCGATTTGGAAGGCACCAGAATCCGGAGGAAAAAACCTCTGGGGGAAAGACCAA
AGGATGAGGATGAACGCACAGTGTATGTGGAGTTACTTCCCAAAAATGTTAATCACAGCTGGAT
TGAAAGAGTATTTGGGAAATGTGGCAATGTTGTTTATATAAGTATACCACATTATAAGTCTACT
GGAGATCCAAAGGGATTTGCGTTTGTGGAATTTGAAACAAAAGAACAAGCAGCAAAAGCAATTG
AGTTTCTTAACAACCCACCAGAAGAAGCACCAAGAAAACCTGGCATATTTCCTAAAACAGTGAA
AAATAAGCCCATTCCAGCCTTAAGAGTTGTGGAAGAGAAGAAAAAGAAAAAGAAGAAGAAAGGC
CGAATGAAAAAGGAAGACAATATCCAAGCCAAAGAAGAAAACATGGACACAAGCAACACCAGCG
TCAGTAAAATGAAAAGATCCAGACCCACATCTGAGGGCTCTGACATTGAGTCCACTGAACCCCA
AAAGCAGTCCTCAAAGNAAAAGAAAAAACGGGACAGAGTTGAAGCATCTAGCTTACCTGAAGTC
AGAACAGGGAAGAGGAAGAGAAGCAGCTCTGAAGATGCAGAATCCCTAGCTCCCCGATCAAAAG
TAAAGAAAATTATTCAGAAAGACATCATTAAGGAAGCATCAGAAGCTTCCAAGGAAAATAGAGA
TATAGAAATCTCTACTGAAGAGGAAAAGGATACTGGAGATCTAAAAGATAGCTCTCTCTTGAAA
ACAAAAAGGAAACATAAGAAAAAACATAAAGAGAGACATAAAATGGGAGAAGAAGTTATACCAT
TAAGAGTACTATCAAAGAGCGAATGGATGGATTTGAAAAAAGAGTATTTAGCACTACAAAAAGC
TAGCATGGCTTCTTTAAAAAAAACAATATCCCAAATAAAATCAGAGTCAGAAATGGAAACAGAC
AGTGGAGTACCTCAAAACACCGGAATGAAAAATGAAAAAACAGCCAACAGGGAAGAGTGTCGCA
CCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCCTGAGTGGAGTGATTGTGAAGATCATTAG
CACAGAGCCTCTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTT
TATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGATTTAAAACTCCTGAGGATGCTC
AAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTC
TGGTGATCACGAACAAAGATATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAG
CCTCGGGAAAAGAAAAGAGGCACTGAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAA
AGACTCAACAAGCGAGTAAACACATAAGATTTTCTGAATATGATTGAAAAAAAAAAACAGTTCA
CCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCAC
TGCATAATTAATGTGTTTTTAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTT
TTTTCTAGAGACAAATACGATGTATACCACAATTTTTCTTAAATATTTTATTTGTTGAAATTAT
CTTAGATGTCAGTGTCAGGTGATTTAGTAAATAAATGTGTTTTGAACATTA

hide sequence

RefSeq Acc Id:

XM_034959020 ⟹ XP_034814911

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,437 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,007,851 - 111,029,020 (+)	NCBI
Mhudiblu_PPA_v0	4	105,128,335 - 105,149,498 (+)	NCBI

RefSeq Acc Id:

XM_034959021 ⟹ XP_034814912

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,798 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,008,212 - 111,029,020 (+)	NCBI
Mhudiblu_PPA_v0	4	105,128,686 - 105,149,498 (+)	NCBI

RefSeq Acc Id:

XM_034959022 ⟹ XP_034814913

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,437 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,007,851 - 111,029,020 (+)	NCBI
Mhudiblu_PPA_v0	4	105,128,335 - 105,149,498 (+)	NCBI

RefSeq Acc Id:

XM_034959024 ⟹ XP_034814915

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,535 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,007,949 - 111,029,020 (+)	NCBI
Mhudiblu_PPA_v0	4	105,128,363 - 105,149,498 (+)	NCBI

RefSeq Acc Id:

XM_055111724 ⟹ XP_054967699

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,454 - 110,735,586 (+)	NCBI
NHGRI_mPanPan1	4	111,007,910 - 111,029,020 (+)	NCBI

RefSeq Acc Id:

XM_055111725 ⟹ XP_054967700

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,437 - 110,731,210 (+)	NCBI
NHGRI_mPanPan1	4	111,007,851 - 111,024,639 (+)	NCBI

RefSeq Acc Id:

XM_063603573 ⟹ XP_063459643

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	110,714,887 - 110,735,586 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008953648	(Get FASTA)	NCBI Sequence Viewer
	XP_034814911	(Get FASTA)	NCBI Sequence Viewer
	XP_034814912	(Get FASTA)	NCBI Sequence Viewer
	XP_034814913	(Get FASTA)	NCBI Sequence Viewer
	XP_034814915	(Get FASTA)	NCBI Sequence Viewer
	XP_054967699	(Get FASTA)	NCBI Sequence Viewer
	XP_054967700	(Get FASTA)	NCBI Sequence Viewer
	XP_063459643	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000030954.1

RefSeq Acc Id:	XP_008953648 ⟸ XM_008955400
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BNI7 (UniProtKB/TrEMBL)
- Sequence:	show sequence METESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKS RDGYVDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKDEDERTVY VELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEE APRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSVSKMKRSRP TSEGSDIESTEPQKQSSKXKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKDI IKEASEASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEW MDLKKEYLALQKASMASLKKTISQIKSESEMETDSGVPQNTGMKNEKTANREECRTQEKVNATG PQFLSGVIVKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTE INKKHCWKLEILSGDHEQRYWQKILVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASKHI RFSEYD hide sequence

RefSeq Acc Id:	XP_034814913 ⟸ XM_034959022
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BNI7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034814911 ⟸ XM_034959020
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_034814915 ⟸ XM_034959024
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9BNI7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034814912 ⟸ XM_034959021
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSPPAP00000030954 ⟸ ENSPPAT00000053818

RefSeq Acc Id:	XP_054967700 ⟸ XM_055111725
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_054967699 ⟸ XM_055111724
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063459643 ⟸ XM_063603573
- Peptide Label:	isoform X3

Protein Domains

HTH La-type RNA-binding RRM XRRM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000038420	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000053818.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	3.30.70.330	UniProtKB/TrEMBL
InterPro	La_dom_prot	UniProtKB/TrEMBL
	La_HTH	UniProtKB/TrEMBL
	La_xRRM	UniProtKB/TrEMBL
	LARP7_La	UniProtKB/TrEMBL
	LARP7_RRM1	UniProtKB/TrEMBL
	LARP7_RRM2	UniProtKB/TrEMBL
	Lupus_La	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	LARP7	ENTREZGENE
PANTHER	LA-RELATED PROTEIN 7	UniProtKB/TrEMBL
	PTHR22792	UniProtKB/TrEMBL
Pfam	PF05383	UniProtKB/TrEMBL
	RRM_1	UniProtKB/TrEMBL
	RRM_3	UniProtKB/TrEMBL
PRINTS	LUPUSLA	UniProtKB/TrEMBL
PROSITE	HTH_LA	UniProtKB/TrEMBL
	RRM	UniProtKB/TrEMBL
	XRRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
	SM00715	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF54928	UniProtKB/TrEMBL
UniProt	A0A2R9BNI7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-09-03	LARP7	La ribonucleoprotein 7, transcriptional regulator	LARP7	La ribonucleoprotein domain family member 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM