LOC100979946 (T-cell surface glycoprotein CD3 delta chain) - Rat Genome Database

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Gene: LOC100979946 (T-cell surface glycoprotein CD3 delta chain) Pan paniscus
Analyze
Symbol: LOC100979946 (Ensembl: CD3D)
Name: T-cell surface glycoprotein CD3 delta chain (Ensembl:CD3 delta subunit of T-cell receptor complex)
RGD ID: 11759381
Description: ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN cell surface receptor signaling pathway (inferred); positive thymic T cell selection (inferred); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); FOUND IN alpha-beta T cell receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD3D; CD3d molecule
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,038,840 - 119,044,827 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,145,509 - 120,149,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,174,007 - 113,179,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,105,868 - 117,111,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,105,868 - 117,111,051 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100979946
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,038,840 - 119,044,827 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,145,509 - 120,149,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,174,007 - 113,179,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,105,868 - 117,111,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,105,868 - 117,111,051 (-)Ensemblpanpan1.1panPan2
CD3D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,338,954 - 118,342,705 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11118,339,075 - 118,342,705 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,209,669 - 118,213,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,714,999 - 117,718,669 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411117,710,474 - 117,718,533NCBI
Celera11115,367,658 - 115,371,328 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,143,683 - 114,147,356 (-)NCBIHuRef
CHM1_111118,096,225 - 118,099,892 (-)NCBICHM1_1
T2T-CHM13v2.011118,355,312 - 118,360,628 (-)NCBIT2T-CHM13v2.0
Cd3d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,893,067 - 44,898,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,893,084 - 44,898,637 (+)EnsemblGRCm39 Ensembl
GRCm38944,981,769 - 44,987,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,981,786 - 44,987,339 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,789,869 - 44,795,135 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,732,876 - 44,737,416 (+)NCBIMGSCv36mm8
Celera942,246,904 - 42,252,171 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Cd3d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,184,573 - 54,190,112 (+)NCBIGRCr8
mRatBN7.2845,287,803 - 45,293,342 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,288,749 - 45,301,809 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,784,363 - 50,788,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,063,089 - 49,067,694 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,933,645 - 46,938,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,282,502 - 49,287,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,282,460 - 49,287,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,900,331 - 47,905,113 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,932,151 - 47,936,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,940,916 - 47,945,510 (+)NCBI
Celera844,873,511 - 44,878,104 (+)NCBICelera
RH 3.4 Map8450.1RGD
Cytogenetic Map8q22NCBI
Cd3d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,480,977 - 19,484,721 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,481,059 - 19,484,890 (-)NCBIChiLan1.0ChiLan1.0
CD3D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,392,841 - 15,396,745 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,389,243 - 15,396,750 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,443,561 - 15,447,497 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,335,138 - 15,339,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,331,562 - 15,339,070 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,473,389 - 15,477,325 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,376,847 - 15,380,783 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,417,998 - 15,421,934 (+)NCBIUU_Cfam_GSD_1.0
Cd3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,478,720 - 100,482,225 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,399,845 - 3,403,634 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,400,129 - 3,403,628 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD3D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,637,129 - 45,644,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1945,640,475 - 45,644,153 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,681,602 - 50,685,279 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD3D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,715,148 - 109,719,576 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,713,017 - 109,719,950 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,315,112 - 16,320,264 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd3d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478413,733,403 - 13,737,356 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478413,733,465 - 13,754,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000013675   ⟹   ENSPPAP00000002913
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11117,105,868 - 117,111,051 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000013724   ⟹   ENSPPAP00000002932
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11117,105,956 - 117,109,395 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000013726   ⟹   ENSPPAP00000002934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11117,105,956 - 117,109,395 (-)Ensembl
RefSeq Acc Id: XM_003820054   ⟹   XP_003820102
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29119,038,840 - 119,044,809 (-)NCBI
NHGRI_mPanPan111120,145,509 - 120,149,139 (-)NCBI
Mhudiblu_PPA_v011113,174,007 - 113,179,198 (-)NCBI
PanPan1.111117,105,868 - 117,111,051 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063608790   ⟹   XP_063464860
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29119,038,840 - 119,044,827 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003820102 (Get FASTA)   NCBI Sequence Viewer  
  XP_063464860 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000002913.1
  ENSPPAP00000002932.1
  ENSPPAP00000002934.1
RefSeq Acc Id: XP_003820102   ⟸   XM_003820054
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZGT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000002913   ⟸   ENSPPAT00000013675
RefSeq Acc Id: ENSPPAP00000002934   ⟸   ENSPPAT00000013726
RefSeq Acc Id: ENSPPAP00000002932   ⟸   ENSPPAT00000013724
RefSeq Acc Id: XP_063464860   ⟸   XM_063608790
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZDG1 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000012538 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000013675.1 UniProtKB/TrEMBL
  ENSPPAT00000013724.1 UniProtKB/TrEMBL
  ENSPPAT00000013726.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  YojJ-like UniProtKB/TrEMBL
InterPro CD3_esu/gsu/dsu UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_4 UniProtKB/TrEMBL
  Phos_immunorcpt_sig_ITAM UniProtKB/TrEMBL
KEGG Report pps:100979946 UniProtKB/TrEMBL
NCBI Gene CD3D ENTREZGENE
PANTHER PTHR10570 UniProtKB/TrEMBL
  PTHR10570:SF5 UniProtKB/TrEMBL
Pfam Ig_4 UniProtKB/TrEMBL
  ITAM UniProtKB/TrEMBL
PROSITE ITAM_1 UniProtKB/TrEMBL
SMART ITAM UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R8ZDG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZGT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZJQ0_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 LOC100979946  T-cell surface glycoprotein CD3 delta chain  CD3D  CD3d molecule  Symbol and/or name change 5135510 APPROVED