NMB (neuromedin B) - Rat Genome Database

Name: NMB
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NMB (neuromedin B) Pan paniscus

Analyze

Symbol:

NMB

Name:

neuromedin B

RGD ID:

11754291

Description:

ENCODES a protein that exhibits neuromedin B receptor binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); arachidonic acid secretion (ortholog); Leydig cell proliferation (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); neuron projection (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuromedin-B

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NMB (neuromedin B)	NCBI	Ortholog
Mus musculus (house mouse):	Nmb (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nmb (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nmb (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NMB (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nmb (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NMB (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NMB (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nmb (neuromedin B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	73,611,720 - 73,614,880 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	77,827,886 - 77,831,046 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	63,322,869 - 63,326,989 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	82,646,630 - 82,650,894 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

genetic disease (ISO)

obesity (ISO)

Pruritus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antiviral innate immune response (ISO)

arachidonic acid secretion (ISO)

Leydig cell proliferation (ISO)

negative regulation of hormone secretion (ISO)

negative regulation of interleukin-6 production (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of hormone secretion (ISO)

positive regulation of interferon-alpha production (ISO)

positive regulation of osteoclast proliferation (ISO)

positive regulation of respiratory gaseous exchange (ISO)

positive regulation of testosterone secretion (ISO)

sensory perception of itch (ISO)

sneeze reflex (ISO)

Cellular Component

extracellular space (ISO)

neuron projection (ISO)

Molecular Function

neuromedin B receptor binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NMB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	73,611,720 - 73,614,880 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	77,827,886 - 77,831,046 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	63,322,869 - 63,326,989 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	82,646,630 - 82,650,894 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

NMB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	84,655,132 - 84,658,199 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	84,655,129 - 84,658,563 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	85,198,363 - 85,201,430 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	82,999,364 - 83,002,806 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	82,999,365 - 83,002,806	NCBI
Celera	15	61,623,887 - 61,627,329 (-)	NCBI		Celera
Cytogenetic Map	15	q25.2	NCBI
HuRef	15	61,284,258 - 61,287,701 (-)	NCBI		HuRef
CHM1_1	15	85,039,491 - 85,042,934 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	82,407,545 - 82,410,612 (-)	NCBI		T2T-CHM13v2.0

Nmb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	80,551,975 - 80,554,810 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	80,551,975 - 80,554,824 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	80,902,227 - 80,905,062 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	80,902,227 - 80,905,076 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	88,047,113 - 88,049,957 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	80,775,749 - 80,778,548 (-)	NCBI		MGSCv36	mm8
Celera	7	78,310,817 - 78,313,649 (-)	NCBI		Celera
Cytogenetic Map	7	D3	NCBI
cM Map	7	45.71	NCBI

Nmb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	144,278,678 - 144,290,523 (-)	NCBI		GRCr8
mRatBN7.2	1	134,869,446 - 134,875,507 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,869,446 - 134,872,190 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	142,784,323 - 142,787,067 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,953,741 - 149,956,485 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,866,879 - 142,869,626 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	142,721,263 - 142,724,646 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	142,721,002 - 142,724,511 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	143,673,434 - 143,676,833 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	137,097,463 - 137,100,207 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	126,922,458 - 126,925,202 (-)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

Nmb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	14,467,650 - 14,470,515 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	14,467,648 - 14,470,645 (+)	NCBI	ChiLan1.0	ChiLan1.0

NMB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	53,927,891 - 53,931,129 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	53,927,900 - 53,931,069 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	56,567,430 - 56,570,667 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	54,347,851 - 54,351,088 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	54,347,853 - 54,351,029 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	53,866,194 - 53,869,430 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	54,075,504 - 54,078,740 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	54,417,009 - 54,420,268 (-)	NCBI		UU_Cfam_GSD_1.0

Nmb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	129,618,979 - 129,622,145 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	16,712,363 - 16,715,749 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	16,712,382 - 16,715,397 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NMB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	52,883,128 - 52,886,642 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	52,880,817 - 52,886,651 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

NMB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	3,703,390 - 3,706,463 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666059	43,354,867 - 43,358,309 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nmb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	17,902,892 - 17,906,592 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624768	17,903,116 - 17,906,340 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034939352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034939353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_034939352 ⟹ XP_034795243

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	73,611,720 - 73,614,880 (-)	NCBI
NHGRI_mPanPan1	15	77,827,886 - 77,831,046 (-)	NCBI
Mhudiblu_PPA_v0	15	63,322,869 - 63,326,989 (-)	NCBI

RefSeq Acc Id:

XM_034939353 ⟹ XP_034795244

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	73,611,720 - 73,614,877 (-)	NCBI
NHGRI_mPanPan1	15	77,827,886 - 77,831,044 (-)	NCBI
Mhudiblu_PPA_v0	15	63,322,869 - 63,326,028 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_034795243	(Get FASTA)	NCBI Sequence Viewer
	XP_034795244	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_034795243 ⟸ XM_034939352
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_034795244 ⟸ XM_034939353
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	NMB	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD